Aliases for PABPC1L Gene
External Ids for PABPC1L Gene
Previous HGNC Symbols for PABPC1L Gene
Previous GeneCards Identifiers for PABPC1L Gene
This gene belongs to the polyadenylate-binding protein type-1 family of proteins. Members of this family bind to the polyA tails of mRNAs to regulate mRNA stability and translation. The mouse ortholog of this gene is required for female fertility. In human, expression of a functional protein is regulated by alternative splicing. The protein-coding splice variant for this gene is abundantly expressed in human oocytes, while a noncoding splice variant subject to nonsense-mediated decay is the predominant splice variant expressed in somatic tissues. [provided by RefSeq, Aug 2019]
GeneCards Summary for PABPC1L Gene
PABPC1L (Poly(A) Binding Protein Cytoplasmic 1 Like) is a Protein Coding gene. Diseases associated with PABPC1L include Acute Endophthalmitis. Among its related pathways are mRNA surveillance pathway and RNA transport. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is PABPC1.