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Aliases for P2RY12 Gene

Aliases for P2RY12 Gene

  • Purinergic Receptor P2Y12 2 3 5
  • Purinergic Receptor P2Y, G-Protein Coupled, 12 2 3
  • P2Y12 Platelet ADP Receptor 3 4
  • ADP-Glucose Receptor 3 4
  • P2Y(ADP) 3 4
  • P2Y(Cyc) 3 4
  • P2T(AC) 3 4
  • P2Y(AC) 3 4
  • ADPG-R 3 4
  • SP1999 3 4
  • HORK3 3 4
  • P2Y12 3 4
  • Putative G-Protein Coupled Receptor 3
  • G-Protein Coupled Receptor SP1999 3
  • Gi-Coupled ADP Receptor HORK3 3
  • Purinergic Receptor P2RY12 3
  • P2Y Purinoceptor 12 3
  • P2Y(12)R 3
  • BDPLT8 3

External Ids for P2RY12 Gene

Previous GeneCards Identifiers for P2RY12 Gene

  • GC03M147996
  • GC03M151887
  • GC03M152336
  • GC03M152376
  • GC03M152538
  • GC03M151055
  • GC03M148428

Summaries for P2RY12 Gene

Entrez Gene Summary for P2RY12 Gene

  • The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

GeneCards Summary for P2RY12 Gene

P2RY12 (Purinergic Receptor P2Y12) is a Protein Coding gene. Diseases associated with P2RY12 include Bleeding Disorder, Platelet-Type, 8 and Drug Metabolism, Poor, Cyp2c19-Related. Among its related pathways are ADP signalling through P2Y purinoceptor 12 and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled adenosine receptor activity. An important paralog of this gene is P2RY13.

UniProtKB/Swiss-Prot for P2RY12 Gene

  • Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.

Tocris Summary for P2RY12 Gene

  • P2Y receptors are G-protein-coupled receptors that respond to extracellular purine and pyrimidine nucleotides. To date, eight mammalian P2Y receptors are known (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11-14) as well as the non-mammalian p2y3, p2y8 and p2y receptors.

Gene Wiki entry for P2RY12 Gene

PharmGKB "VIP" Summary for P2RY12 Gene

Additional gene information for P2RY12 Gene

No data available for CIViC summary , fRNAdb sequence ontologies and piRNA Summary for P2RY12 Gene

Genomics for P2RY12 Gene

GeneHancer (GH) Regulatory Elements for P2RY12 Gene

Promoters and enhancers for P2RY12 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J151382 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 674.3 +1.1 1073 2.9 PKNOX1 EBF1 BATF RELA NFATC1 EED ATF7 ETV6 IKZF2 RUNX3 P2RY12 GPR87 P2RY13 MED12L
GH03J151340 Promoter 0.5 EPDnew 650.3 +44.0 43970 0.1 P2RY12 P2RY13 MED12L
GH03J151392 Enhancer 0.5 ENCODE 19.1 -9.0 -8989 1.6 ZNF766 NANOG SCRT2 POU5F1 P2RY12 GC03P151434 MED12L
GH03J151224 Enhancer 1.3 FANTOM5 Ensembl ENCODE 4.8 +157.6 157596 4.5 ATF1 FOXA2 IRF4 BRCA1 RAD21 RFX5 YY1 ARID2 ZNF143 FOS P2RY14 P2RY12 GC03M151222 GPR171 MED12L
GH03J151461 Promoter/Enhancer 1.2 EPDnew Ensembl 4.7 -76.2 -76189 0.8 USF1 ZNF335 ZNF121 ZFHX2 GLIS2 PATZ1 SCRT2 ZNF600 ZBTB20 SP3 IGSF10 P2RY12 MRPL42P6 GC03P151434
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around P2RY12 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the P2RY12 gene promoter:
  • PPAR-alpha
  • HFH-1
  • LCR-F1
  • Pax-2a
  • Arnt
  • AhR
  • Pax-2
  • POU3F2
  • FOXO1
  • FOXO1a

Genomic Locations for P2RY12 Gene

Genomic Locations for P2RY12 Gene
chr3:151,336,843-151,384,812
(GRCh38/hg38)
Size:
47,970 bases
Orientation:
Minus strand
chr3:151,055,168-151,102,600
(GRCh37/hg19)
Size:
47,433 bases
Orientation:
Minus strand

Genomic View for P2RY12 Gene

Genes around P2RY12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
P2RY12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for P2RY12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for P2RY12 Gene

Proteins for P2RY12 Gene

  • Protein details for P2RY12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H244-P2Y12_HUMAN
    Recommended name:
    P2Y purinoceptor 12
    Protein Accession:
    Q9H244
    Secondary Accessions:
    • D3DNJ5
    • Q546J7

    Protein attributes for P2RY12 Gene

    Size:
    342 amino acids
    Molecular mass:
    39439 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for P2RY12 Gene

neXtProt entry for P2RY12 Gene

Post-translational modifications for P2RY12 Gene

  • Glycosylation at isoforms=13 and Asn6
  • Modification sites at PhosphoSitePlus

Other Protein References for P2RY12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for P2RY12 Gene

Domains & Families for P2RY12 Gene

Gene Families for P2RY12 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Disease related genes
  • FDA approved drug targets
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for P2RY12 Gene

Suggested Antigen Peptide Sequences for P2RY12 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H244

UniProtKB/Swiss-Prot:

P2Y12_HUMAN :
  • The transmembrane domain is composed of seven transmembrane helices; most of these are not strictly perpendicular to the plane of the membrane, but are tilted and/or kinked. Agonist binding promotes a conformation change in the extracellular loops that leads to an inward movement of the transmembrane helices. Antagonists such as AZD1283 can bind to an overlapping site, but block the inward movement of the transmembrane helices (PubMed:24670650, PubMed:24784220).
  • Belongs to the G-protein coupled receptor 1 family.
Domain:
  • The transmembrane domain is composed of seven transmembrane helices; most of these are not strictly perpendicular to the plane of the membrane, but are tilted and/or kinked. Agonist binding promotes a conformation change in the extracellular loops that leads to an inward movement of the transmembrane helices. Antagonists such as AZD1283 can bind to an overlapping site, but block the inward movement of the transmembrane helices (PubMed:24670650, PubMed:24784220).
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with P2RY12: view

Function for P2RY12 Gene

Molecular function for P2RY12 Gene

UniProtKB/Swiss-Prot Function:
Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.

Gene Ontology (GO) - Molecular Function for P2RY12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001609 G-protein coupled adenosine receptor activity IEA --
GO:0001621 ADP receptor activity IMP 12578987
GO:0004871 obsolete signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0005085 guanyl-nucleotide exchange factor activity TAS --
genes like me logo Genes that share ontologies with P2RY12: view
genes like me logo Genes that share phenotypes with P2RY12: view

Human Phenotype Ontology for P2RY12 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for P2RY12 Gene

MGI Knock Outs for P2RY12:

Animal Model Products

  • Taconic Biosciences Mouse Models for P2RY12

miRNA for P2RY12 Gene

miRTarBase miRNAs that target P2RY12

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for P2RY12 Gene

Localization for P2RY12 Gene

Subcellular locations from UniProtKB/Swiss-Prot for P2RY12 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for P2RY12 gene
Compartment Confidence
plasma membrane 5
extracellular 2
cytoskeleton 2
mitochondrion 2
cytosol 1

Gene Ontology (GO) - Cellular Components for P2RY12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
GO:0005886 plasma membrane TAS,ISS --
GO:0005887 integral component of plasma membrane IBA --
GO:0005901 caveola IEA --
GO:0009897 external side of plasma membrane IEA --
genes like me logo Genes that share ontologies with P2RY12: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for P2RY12 Gene

Pathways & Interactions for P2RY12 Gene

genes like me logo Genes that share pathways with P2RY12: view

Pathways by source for P2RY12 Gene

Gene Ontology (GO) - Biological Process for P2RY12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001973 adenosine receptor signaling pathway IEA --
GO:0006930 substrate-dependent cell migration, cell extension ISS,IEA --
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS --
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with P2RY12: view

No data available for SIGNOR curated interactions for P2RY12 Gene

Drugs & Compounds for P2RY12 Gene

(74) Drugs for P2RY12 Gene - From: DrugBank, PharmGKB, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Clopidogrel Approved Pharma antagonist, Target P2Y12 receptor antagonist 814
Ticagrelor Approved Pharma Target, inhibitor P2Y12 receptor antagonist 339
Prasugrel Approved Pharma inhibitor, Target, antagonist ADP receptor inhibitor 0
Cangrelor Approved Pharma Antagonist, Target, inhibitor 21
Treprostinil Approved, Investigational Pharma Full agonist, Agonist, agonist, Target 92

(22) Additional Compounds for P2RY12 Gene - From: Novoseek, HMDB, and IUPHAR

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Full agonist, Agonist, Partial agonist, Antagonist, Gating inhibitor 58-64-0
active metabolite of clopidogrel
Antagonist
Adpbetas
Full agonist, Agonist
ATPgammaS
Full agonist, Agonist, Partial agonist
AZD6140
Antagonist

(5) Tocris Compounds for P2RY12 Gene

Compound Action Cas Number
2-Methylthioadenosine diphosphate trisodium salt Potent agonist for P2Y1, P2Y12 and P2Y13 475193-31-8
MRS 2365 Highly potent and selective P2Y1 agonist 436847-09-5
MRS 2690 Potent P2Y14 agonist 15039-58-4
MRS 2693 trisodium salt Selective P2Y6 agonist 1448858-83-0
PSB 0474 Potent and selective P2Y6 agonist 917567-60-3
genes like me logo Genes that share compounds with P2RY12: view

Transcripts for P2RY12 Gene

mRNA/cDNA for P2RY12 Gene

(2) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(28) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for P2RY12 Gene

Purinergic receptor P2Y, G-protein coupled, 12:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for P2RY12 Gene

No ASD Table

Relevant External Links for P2RY12 Gene

GeneLoc Exon Structure for
P2RY12
ECgene alternative splicing isoforms for
P2RY12

Expression for P2RY12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for P2RY12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for P2RY12 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x8.0), Brain - Substantia nigra (x7.7), Brain - Amygdala (x5.4), Brain - Hippocampus (x4.4), and Brain - Hypothalamus (x4.4).

Protein differential expression in normal tissues from HIPED for P2RY12 Gene

This gene is overexpressed in Frontal cortex (26.2), Pancreatic juice (24.2), and Peripheral blood mononuclear cells (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for P2RY12 Gene



Protein tissue co-expression partners for P2RY12 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of P2RY12 Gene:

P2RY12

SOURCE GeneReport for Unigene cluster for P2RY12 Gene:

Hs.591281

mRNA Expression by UniProt/SwissProt for P2RY12 Gene:

Q9H244-P2Y12_HUMAN
Tissue specificity: Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.

Evidence on tissue expression from TISSUES for P2RY12 Gene

  • Nervous system(4.8)
  • Blood(4.7)

Phenotype-based relationships between genes and organs from Gene ORGANizer for P2RY12 Gene

Germ Layers:
  • ectoderm
  • mesoderm
Systems:
  • cardiovascular
  • integumentary
Regions:
Head and neck:
  • face
  • head
  • nose
General:
  • blood
  • blood vessel
  • coagulation system
  • skin
genes like me logo Genes that share expression patterns with P2RY12: view

Orthologs for P2RY12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for P2RY12 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia P2RY12 34 33
  • 99.42 (n)
OneToOne
dog
(Canis familiaris)
Mammalia P2RY12 34 33
  • 90.76 (n)
OneToOne
cow
(Bos Taurus)
Mammalia P2RY12 34 33
  • 88.5 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia P2RY12 34
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia P2ry12 16 34 33
  • 83.13 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia P2RY12 34
  • 83 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia P2ry12 33
  • 82.83 (n)
chicken
(Gallus gallus)
Aves P2RY12 34
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia P2RY12 34
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia p2ry12 33
  • 65.37 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100149618 33
  • 59.02 (n)
p2ry12 34
  • 52 (a)
OneToOne
Species where no ortholog for P2RY12 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for P2RY12 Gene

ENSEMBL:
Gene Tree for P2RY12 (if available)
TreeFam:
Gene Tree for P2RY12 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for P2RY12: view image

Paralogs for P2RY12 Gene

Paralogs for P2RY12 Gene

(12) SIMAP similar genes for P2RY12 Gene using alignment to 1 proteins:

  • P2Y12_HUMAN
genes like me logo Genes that share paralogs with P2RY12: view

Variants for P2RY12 Gene

Sequence variations from dbSNP and Humsavar for P2RY12 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs121917885 pathogenic, Platelet-type bleeding disorder 8, Bleeding disorder, platelet-type 8 (BDPLT8) [MIM:609821] 151,338,079(-) C/T coding_sequence_variant, missense_variant
rs121917886 pathogenic, Platelet-type bleeding disorder 8, Bleeding disorder, platelet-type 8 (BDPLT8) [MIM:609821] 151,338,053(-) G/A coding_sequence_variant, missense_variant
VAR_072802 Bleeding disorder, platelet-type 8 (BDPLT8) [MIM:609821] p.His187Gln
rs6785930 benign, not specified 151,338,828(-) G/A/T coding_sequence_variant, missense_variant, synonymous_variant
rs6809699 benign, not specified 151,338,810(-) A/C coding_sequence_variant, synonymous_variant

Structural Variations from Database of Genomic Variants (DGV) for P2RY12 Gene

Variant ID Type Subtype PubMed ID
esv1169457 CNV deletion 17803354
esv2400186 CNV deletion 18987734
esv2726056 CNV deletion 23290073
esv2726057 CNV deletion 23290073
esv3569057 CNV loss 25503493
nsv592045 CNV gain 21841781
nsv829757 CNV loss 17160897
nsv954492 CNV duplication 24416366

Variation tolerance for P2RY12 Gene

Residual Variation Intolerance Score: 36.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.46; 28.49% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for P2RY12 Gene

Human Gene Mutation Database (HGMD)
P2RY12
SNPedia medical, phenotypic, and genealogical associations of SNPs for
P2RY12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for P2RY12 Gene

Disorders for P2RY12 Gene

MalaCards: The human disease database

(10) MalaCards diseases for P2RY12 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
bleeding disorder, platelet-type, 8
  • bdplt8
drug metabolism, poor, cyp2c19-related
  • clopidogrel, impaired responsiveness to
clopidogrel resistance
  • cyp2c19-related poor drug metabolism
peripheral artery disease
  • peripheral arterial diseases
coronary thrombosis
  • coronary artery thrombosis
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

P2Y12_HUMAN
  • Bleeding disorder, platelet-type 8 (BDPLT8) [MIM:609821]: A condition characterized by mild to moderate mucocutaneous bleeding, and excessive bleeding after surgery or trauma. The defect is due to severe impairment of platelet response to ADP resulting in defective platelet aggregation. {ECO:0000269 PubMed:11196645, ECO:0000269 PubMed:12578987, ECO:0000269 PubMed:25428217}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for P2RY12

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with P2RY12: view

No data available for Genatlas for P2RY12 Gene

Publications for P2RY12 Gene

  1. Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor. (PMID: 11502873) Takasaki J … Furuichi K (Molecular pharmacology 2001) 2 3 4 22 58
  2. [Genetic variants of platelet ADP receptor P2Y12 associated with changed platelet functional activity and development of cardiovascular diseases]. (PMID: 19334620) Sirotkina OV … Shvartsman AL (Genetika 2009) 3 22 44 58
  3. Common variation in the platelet receptor P2RY12 gene is associated with residual on-clopidogrel platelet reactivity in patients undergoing elective percutaneous coronary interventions. (PMID: 20031628) Rudez G … Hackeng CM (Circulation. Cardiovascular genetics 2009) 3 22 44 58
  4. Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism. (PMID: 17707382) Zee RY … Ridker PM (Atherosclerosis 2008) 3 22 44 58
  5. P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease. (PMID: 17995973) Bierend A … Böger RH (British journal of clinical pharmacology 2008) 3 22 44 58

Products for P2RY12 Gene

Sources for P2RY12 Gene

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