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The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor.... See more...
Aliases for P2RY11 Gene
Aliases for P2RY11 Gene
External Ids for P2RY11 Gene
- HGNC: 8540
- Entrez Gene: 5032
- Ensembl: ENSG00000244165
- OMIM: 602697
- UniProtKB: Q96G91
Previous GeneCards Identifiers for P2RY11 Gene
- GC19P010343
- GC19P010445
- GC19P010068
- GC19P010083
- GC19P010222
- GC19P009823
- GC19P010113
- GC19P010116
- GC19P010135
- GC19P010137
- GC19P010142
- GC19P010146
- GC19P010117
- GC19P010119
- GC19P010121
- GC19P010125
- GC19P010127
- GC19P010129
- GC19P010131
- GC19P010133
Summaries for P2RY11 Gene
-
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008]
GeneCards Summary for P2RY11 Gene
P2RY11 (Purinergic Receptor P2Y11) is a Protein Coding gene. Diseases associated with P2RY11 include Narcolepsy 1 and Narcolepsy. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and G protein-coupled purinergic nucleotide receptor activity. An important paralog of this gene is RXFP3.
UniProtKB/Swiss-Prot Summary for P2RY11 Gene
-
Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.
-
P2Y receptors are G-protein-coupled receptors that respond to extracellular purine and pyrimidine nucleotides. To date, eight mammalian P2Y receptors are known (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11-14) as well as the non-mammalian p2y3, p2y8 and p2y receptors.
Additional gene information for P2RY11 Gene
- HGNC(8540)
- Entrez Gene(5032)
- Ensembl(ENSG00000244165)
- OMIM(602697)
- UniProtKB(Q96G91)
- Open Targets Platform(ENSG00000244165)
- Monarch Initiative
- Search for P2RY11 at DataMed
- Search for P2RY11 at HumanCyc
No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for P2RY11 Gene
Genomics for P2RY11 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for P2RY11 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around P2RY11 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for P2RY11
- Top Transcription factor binding sites by QIAGEN in the P2RY11 gene promoter:
-
- AREB6
- c-Myc
- FOXO1
- FOXO1a
- GATA-2
- LyF-1
- Max
- Pax-6
- Zic3
Genomic Locations for P2RY11 Gene
Genomic Locations for P2RY11 Gene
- chr19:10,111,693-10,115,372
- (GRCh38/hg38)
- Size:
- 3,680 bases
- Orientation:
- Plus strand
- chr19:10,222,197-10,226,065
- (GRCh37/hg19)
- Size:
- 3,869 bases
- Orientation:
- Plus strand
Genomic View for P2RY11 Gene
Genes around P2RY11 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by HGNC
- 19p13.2 by Entrez Gene
- 19p13.2 by Ensembl
P2RY11 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for P2RY11 Gene
Proteins for P2RY11 Gene
-
Protein details for P2RY11 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96G91-P2Y11_HUMAN
- Recommended name:
- P2Y purinoceptor 11
- Protein Accession:
- Q96G91
- B2R8X9
- O43190
- Q9BYU4
- Q9H170
Protein attributes for P2RY11 Gene
- Size:
- 374 amino acids
- Molecular mass:
- 40345 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAB88674.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAC18877.1; Type=Erroneous initiation; Evidence={ECO:0000305};
- Miscellaneous:
-
- A chimeric transcript, characterized by the first third of PPAN exon 12 joined to P2RY11 exon 2, has been detected. It is possibly produced by trans-splicing. The chimeric transcript is widely expressed and can be induced by retinoic acid during the granulocytic differentiation of the HL-60 cell line. The resulting chimeric protein shows a much lower activity than the non-chimeric P2RY11 gene product, but qualitatively indistinguishable (PubMed:11278528).
Protein Expression for P2RY11 Gene
Post-translational modifications for P2RY11 Gene
Other Protein References for P2RY11 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences P2RY11 / P2Y11 Antibody (LS-A867) and P2RY11 / P2Y11 Antibody (LS-A866)
- Novus Biologicals Antibodies for P2RY11
-
Abcam antibodies for P2RY11
- Invitrogen Antibodies for P2RY11 (AFLGC-P2RY11)
-
Boster Bio Antibodies for P2RY11
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for P2RY11
- Origene Custom Protein Services for P2RY11
- Novus Biologicals proteins for P2RY11
-
Abcam proteins for P2RY11
No data available for DME Specific Peptides for P2RY11 Gene
Domains & Families for P2RY11 Gene
Gene Families for P2RY11 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for P2RY11 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for P2RY11 Gene
- GenScript: Design optimal peptide antigens:
-
- P2Y purinoceptor 11 (P2Y11_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96G91- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for P2RY11 Gene
Molecular function for P2RY11 Gene
- UniProtKB/Swiss-Prot Function:
- Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.
- UniProtKB/Swiss-Prot Induction:
- Increased by DMSO and retinoic acid.
Phenotypes From GWAS Catalog for P2RY11 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0030594 | neurotransmitter receptor activity | IDA | 18048695 |
| GO:0038023 | signaling receptor activity | TAS | 9405388 |
| GO:0045031 | ATP-activated adenosine receptor activity | IBA,IDA | 18048695 |
Phenotypes for P2RY11 Gene
- GenomeRNAi human phenotypes for P2RY11:
-
- Decreased hepcidin::fluc mRNA expression
- Increased vaccinia virus (VACV) infection
- no effect
- shRNA abundance <= 50%
- Negative genetic interaction between BLM-/- and BLM+/+
- Increased gamma-H2AX phosphorylation
- Decreased viability
- Increased viability
- Increased shRNA abundance (Z-score > 2)
- Decreased POU5F1-GFP protein expression
- Decreased shRNA abundance (Z-score < -2)
- Negative genetic interaction between PTEN-/- and PTEN+/+
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for P2RY11 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for P2RY11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for P2RY11
-
Santa Cruz Biotechnology (SCBT) CRISPR for P2RY11
miRNA for P2RY11 Gene
- miRTarBase miRNAs that target P2RY11
-
- hsa-miR-99a-5p (MIRT048698)
- hsa-miR-1247-5p (MIRT790058)
- hsa-miR-130a-5p (MIRT790103)
- hsa-miR-23a-3p (MIRT790195)
- hsa-miR-23b-3p (MIRT790196)
- hsa-miR-23c (MIRT790197)
- hsa-miR-323a-3p (MIRT790273)
- hsa-miR-3909 (MIRT790363)
- hsa-miR-4707-3p (MIRT790577)
- hsa-miR-6798-3p (MIRT790971)
- hsa-miR-6852-3p (MIRT791029)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for P2RY11
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Clone Products
- Applied Biological Materials (abm): Clones for P2RY11 - Select products 50% OFF >
- * P2RY11 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- Sino Biological Human cDNA Clone for P2RY11
- Addgene plasmids for P2RY11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for P2RY11
Cell Line Products
-
Horizon Cell Lines for P2RY11
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for P2RY11 Gene
Localization for P2RY11 Gene
Subcellular locations from UniProtKB/Swiss-Prot for P2RY11 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 3 |
| extracellular | 2 |
| cytoskeleton | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IC | 18048695 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for P2RY11 Gene
Pathways & Interactions for P2RY11 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peptide ligand-binding receptors | ||
| 2 | Signaling by GPCR | ||
| 3 | RET signaling | ||
| 4 | Nucleotide-like (purinergic) receptors |
.01
|
|
| 5 | GPCR Pathway |
P2Y Receptor Signaling
.38
|
|
Pathways by source for P2RY11 Gene
2 BioSystems pathways for P2RY11 Gene
10 Reactome pathways for P2RY11 Gene
1 KEGG pathway for P2RY11 Gene
1 GeneGo (Thomson Reuters) pathway for P2RY11 Gene
- Signal transduction IP3 signaling
1 Qiagen pathway for P2RY11 Gene
- P2Y Receptor Signaling
Interacting Proteins for P2RY11 Gene
GPS-Prot Interaction Network for P2RY11
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006952 | defense response | TAS | 9405388 |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | IDA,TAS | -- |
| GO:0007190 | activation of adenylate cyclase activity | TAS | 9405388 |
| GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway | TAS | 9405388 |
Drugs & Compounds for P2RY11 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Promethazine | Approved, Investigational | Pharma | Target, inhibitor | 470 | ||
| dATP | Experimental | Pharma | Agonist, Full agonist | 0 | ||
| NAD | Experimental | Pharma | Agonist, Full agonist, Activator | 0 | ||
| Uridine triphosphate | Experimental, Investigational | Pharma | 0 | |||
| ATP | Investigational | Nutra | Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation, Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| UTP |
|
Agonist, Full agonist, Partial agonist |
|
|||
| 2-Methylthioadenosine diphosphate trisodium salt |
|
475193-31-8 |
|
|
(5) Tocris Compounds for P2RY11 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 2-Methylthioadenosine diphosphate trisodium salt | Potent agonist for P2Y1, P2Y12 and P2Y13 | 475193-31-8 |
| MRS 2365 | Highly potent and selective P2Y1 agonist | 436847-09-5 |
| MRS 2690 | Potent P2Y14 agonist | 15039-58-4 |
| MRS 2693 trisodium salt | Selective P2Y6 agonist | 1448858-83-0 |
| PSB 0474 | Potent and selective P2Y6 agonist | 917567-60-3 |
Transcripts for P2RY11 Gene
mRNA/cDNA for P2RY11 Gene
- 1 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000321826 1788 nts (view in UCSC)
- ENST00000471843 554 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for P2RY11 - Select products 50% OFF >
- * P2RY11 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for P2RY11
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for P2RY11
-
Santa Cruz Biotechnology (SCBT) CRISPR for P2RY11
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for P2RY11
- Browse OriGene Inhibitory RNA Products For P2RY11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for P2RY11
Clone Products
- Applied Biological Materials (abm): Clones for P2RY11 - Select products 50% OFF >
- * P2RY11 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for P2RY11
- Addgene plasmids for P2RY11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for P2RY11
Relevant External Links for P2RY11 Gene
- GeneLoc Exon Structure for
- P2RY11
Expression for P2RY11 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Lymph (Hematopoietic System)
This gene is overexpressed in Placenta (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for P2RY11 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for P2RY11
SOURCE GeneReport for Unigene cluster for P2RY11 Gene:
Hs.14468mRNA Expression by UniProt/SwissProt for P2RY11 Gene:
Q96G91-P2Y11_HUMAN
Tissue specificity:
Highest expression in liver and spleen.
Evidence on tissue expression from TISSUES for P2RY11 Gene
- Nervous system(4.6)
- Skin(2.6)
- Heart(2.5)
- Muscle(2.4)
- Spleen(2.4)
- Lymph node(2.4)
- Blood(2.4)
- Kidney(2.3)
- Lung(2.2)
- Intestine(2.1)
- Bone marrow(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for P2RY11 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- nervous
- respiratory
- skeletal muscle
Regions:
Head and neck:
- brain
- cranial nerve
- ear
- eye
- head
- mouth
- pharynx
Thorax:
- heart
General:
- blood vessel
- peripheral nervous system
Primer Products
-
OriGene qPCR primer pairs for P2RY11
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues for P2RY11 Gene
Orthologs for P2RY11 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | P2RY11 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | P2RY11 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | P2RY11 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | P2RY11 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | p2ry11 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | p2ry11 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | ppan 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | lpd-6 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SSF1 31 |
|
ManyToMany | |
| SSF2 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.2660 31 |
|
OneToMany |
- Species where no ortholog for P2RY11 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for P2RY11 Gene
- ENSEMBL:
- Gene Tree for P2RY11 (if available)
- TreeFam:
- Gene Tree for P2RY11 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for P2RY11: view image
Paralogs for P2RY11 Gene
Variants for P2RY11 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for P2RY11 Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 709320 | Likely Benign: not provided | 10,113,811(+) | C/A | MISSENSE_VARIANT,SYNONYMOUS_VARIANT | |
| 716471 | Likely Benign: not provided | 10,114,462(+) | G/A | SYNONYMOUS_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 725779 | Benign: not provided | 10,113,943(+) | C/T | SYNONYMOUS_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 728169 | Likely Benign: not provided | 10,114,297(+) | C/T | SYNONYMOUS_VARIANT,THREE_PRIME_UTR_VARIANT | |
| 728997 | Likely Benign: not provided | 10,114,513(+) | C/G | NONSENSE,THREE_PRIME_UTR_VARIANT |
Residual Variation Intolerance Score:
96.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.60;
12.97% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for P2RY11 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for P2RY11 Gene
Disorders for P2RY11 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| narcolepsy 1 |
|
|
| narcolepsy |
|
|
Search P2RY11 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for P2RY11
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for P2RY11 Gene
Publications for P2RY11 Gene
- Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase. (PMID: 9405388) Communi D … Boeynaems JM (The Journal of biological chemistry 1997) 2 3 4 23
- Increased risk of acute myocardial infarction and elevated levels of C-reactive protein in carriers of the Thr-87 variant of the ATP receptor P2Y11. (PMID: 17135283) Amisten S … Erlinge D (European heart journal 2007) 3 23 41
- Cotranscription and intergenic splicing of human P2Y11 and SSF1 genes. (PMID: 11278528) Communi D … Boeynaems JM (The Journal of biological chemistry 2001) 3 4 23
- Common variants in P2RY11 are associated with narcolepsy. (PMID: 21170044) Kornum BR … Mignot E (Nature genetics 2011) 3 41
- Involvement of P2Y1 and P2Y11 purinoceptors in parasympathetic inhibition of colonic smooth muscle. (PMID: 18048695) King BF … Townsend-Nicholson A (The Journal of pharmacology and experimental therapeutics 2008) 3 23
ExternalLinks
Products for P2RY11 Gene
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- Horizon Cell Lines for P2RY11
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for P2RY11
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for P2RY11
- Search GeneCopoeia for miRNA 3'UTR Target clone products for P2RY11
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for P2RY11
- Boster Bio Antibodies for P2RY11
- Browse Boster Bio ELISA Kits
Sources for P2RY11 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB