Aliases for P2RX6 Gene
Aliases for P2RX6 Gene
External Ids for P2RX6 Gene
- HGNC: 8538
- Entrez Gene: 9127
- Ensembl: ENSG00000099957
- OMIM: 608077
- UniProtKB: O15547
Previous HGNC Symbols for P2RX6 Gene
- P2RXL1
Previous GeneCards Identifiers for P2RX6 Gene
- GC22P019699
- GC22P021399
- GC22P021406
- GC22P004637
- GC22P021415
- GC22P021423
- GC22P021430
- GC22P021440
- GC22P021364
Summaries for P2RX6 Gene
-
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
GeneCards Summary for P2RX6 Gene
P2RX6 (Purinergic Receptor P2X 6) is a Protein Coding gene. Among its related pathways are Platelet homeostasis and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include identical protein binding and ion channel activity. An important paralog of this gene is P2RX5-TAX1BP3.
UniProtKB/Swiss-Prot for P2RX6 Gene
-
Receptor for ATP that acts as a ligand-gated ion channel.
-
P2X receptors are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for P2RX6 Gene
Genomics for P2RX6 Gene
GeneHancer (GH) Regulatory Elements for P2RX6 Gene
Promoters and enhancers for P2RX6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around P2RX6 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the P2RX6 gene promoter:
-
- c-Ets-1
- MIF-1
- Pax-2b
- Pax-2a
- Pax-2
- Olf-1
- MyoD
- CUTL1
- p53
- Lmo2
Regulatory Element Products
Genomic Locations for P2RX6 Gene
Genomic Locations for P2RX6 Gene
- chr22:21,009,808-21,028,830
- (GRCh38/hg38)
- Size:
- 19,023 bases
- Orientation:
- Plus strand
- chr22:21,364,097-21,383,119
- (GRCh37/hg19)
- Size:
- 19,023 bases
- Orientation:
- Plus strand
Genomic View for P2RX6 Gene
Genes around P2RX6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.21 by Entrez Gene
- 22q11.21 by HGNC
- 22q11.21 by Ensembl
P2RX6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for P2RX6 Gene
Proteins for P2RX6 Gene
-
Protein details for P2RX6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O15547-P2RX6_HUMAN
- Recommended name:
- P2X purinoceptor 6
- Protein Accession:
- O15547
- F6V3D7
- Q32MB6
- Q58F04
- Q6IC33
- Q9UL50
Protein attributes for P2RX6 Gene
- Size:
- 441 amino acids
- Molecular mass:
- 48829 Da
- Quaternary structure:
-
- Unlike most P2XRs, P2RX6 does not seem to form homotrimers or heterotrimers.
- SequenceCaution:
-
- Sequence=AAF13303.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAF13303.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part.; Evidence={ECO:0000305}; Sequence=AAH33488.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI09210.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA22046.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA22047.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for P2RX6 Gene
Post-translational modifications for P2RX6 Gene
- N-glycosylated.
- Glycosylation at Asn210, isoforms=2195, and isoforms=2165
- Modification sites at PhosphoSitePlus
Other Protein References for P2RX6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for P2RX6
-
Abcam antibodies for P2RX6
- Invitrogen Antibodies for P2RX6 (AFLGC-P2RX6)
- GeneTex P2RX6 Antibody for P2RX6
-
Boster Bio Antibodies for P2RX6
-
Santa Cruz Biotechnology (SCBT) Antibodies for P2RX6
Protein Products
-
OriGene Purified Proteins for P2RX6
- Search Origene for MassSpec and Protein Over-expression Lysates for P2RX6
- Origene Custom Protein Services for P2RX6
- antibodies-online: Search results for 4 available P2RX6 Proteins ranked by validation data
- Compare Top P2RX6 Proteins
-
Quality Products:
- Search GeneTex for Proteins for P2RX6
Assay Products
No data available for DME Specific Peptides for P2RX6 Gene
Domains & Families for P2RX6 Gene
Gene Families for P2RX6 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for P2RX6 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for P2RX6 Gene
Graphical View of Domain Structure for InterPro Entry
O15547- Family:
-
- Belongs to the P2X receptor family.
Function for P2RX6 Gene
Molecular function for P2RX6 Gene
- UniProtKB/Swiss-Prot Function:
- Receptor for ATP that acts as a ligand-gated ion channel.
Phenotypes From GWAS Catalog for P2RX6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001614 | purinergic nucleotide receptor activity | NAS | 12088286 |
| GO:0004888 | transmembrane signaling receptor activity | TAS | 9242461 |
| GO:0004931 | extracellularly ATP-gated cation channel activity | IEA,NAS | 12088286 |
| GO:0005216 | ion channel activity | IEA | -- |
| GO:0005524 | ATP binding | IEA,NAS | 12088286 |
Phenotypes for P2RX6 Gene
- MGI mutant phenotypes for P2RX6:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for P2RX6:
Animal Models for P2RX6 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for P2RX6
- Cyagen custom Knockout/knockin (KOKI) mouse models for P2RX6
-
CRISPR Products
-
OriGene CRISPR knockouts for P2RX6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for P2RX6
- genomics-online: gRNA clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- Applied Biological Materials CRISPR for P2RX6
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for P2RX6
- GenScript: Design CRISPR guide RNA sequences for P2RX6
miRNA for P2RX6 Gene
- miRTarBase miRNAs that target P2RX6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for P2RX6
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for P2RX6
- genomics-online: shRNA clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
Clone Products
- Sino Biological Human cDNA Clone for P2RX6
- Addgene plasmids for P2RX6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for P2RX6
- Applied Biological Materials Clones for P2RX6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for P2RX6 (P2X6/P2RX6)
Cell Line Products
-
Horizon Cell Lines for P2RX6
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for P2RX6 Gene
Localization for P2RX6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for P2RX6 Gene
- Membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 4 |
| extracellular | 2 |
| cytosol | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
- Cytosol (2)
- Nucleoli (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005639 | integral component of nuclear inner membrane | IBA | -- |
| GO:0005737 | cytoplasm | IDA | 12088286 |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
Pathways & Interactions for P2RX6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Platelet homeostasis | ||
| 2 | Calcium signaling pathway | ||
| 3 | Peptide ligand-binding receptors | ||
| 4 | CREB Pathway | ||
| 5 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
Pathways by source for P2RX6 Gene
4 Reactome pathways for P2RX6 Gene
2 KEGG pathways for P2RX6 Gene
1 Qiagen pathway for P2RX6 Gene
Interacting Proteins for P2RX6 Gene
GPS-Prot Interaction Network for P2RX6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006811 | ion transport | IEA | -- |
| GO:0006812 | cation transport | IBA | -- |
| GO:0006936 | muscle contraction | TAS | 9242461 |
| GO:0007165 | signal transduction | TAS | 9242461 |
| GO:0007596 | blood coagulation | TAS | -- |
No data available for SIGNOR curated interactions for P2RX6 Gene
Drugs & Compounds for P2RX6 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| KN-93 | Pharma | CaMKII inhibitor,selective and cometitive | 0 | |||
| 2-Methylthioadenosine triphosphate tetrasodium salt | Pharma | P2 purinergic agonist | 0 | |||
| NF 157 | Pharma | Selective P2Y11/P2X1 antagonist | 0 | |||
| PPADS tetrasodium salt | Pharma | P2 purinergic antagonist | 0 | |||
| Suramin hexasodium salt | Pharma | Non-selective P2 antagonist | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ATPgammaS tetralithium salt |
|
93839-89-5 |
|
|
(5) Tocris Compounds for P2RX6 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 2-Methylthioadenosine triphosphate tetrasodium salt | P2 purinergic agonist | 100020-57-3 |
| ATPgammaS tetralithium salt | P2 agonist; ATP (Cat. No. 3245) analog | 93839-89-5 |
| NF 157 | Selective P2Y11/P2X1 antagonist | 104869-26-3 |
| PPADS tetrasodium salt | P2 purinergic antagonist | 192575-19-2 |
| Suramin hexasodium salt | Non-selective P2 antagonist | 129-46-4 |
Drug Products
Transcripts for P2RX6 Gene
mRNA/cDNA for P2RX6 Gene
- (19) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (37) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000591411 242 bps (uc062bxe.1)
- ENST00000413302 3687 bps (uc010gsu.2)
- ENST00000442475 2513 bps (uc062bxf.1)
- ENST00000401443 1834 bps (uc002ztz.3)
- ENST00000469722 1186 bps (uc010gst.2)
Unigene Clusters for P2RX6 Gene
CRISPR Products
-
OriGene CRISPR knockouts for P2RX6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for P2RX6
- genomics-online: gRNA clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- Applied Biological Materials CRISPR for P2RX6
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for P2RX6
- GenScript: Design CRISPR guide RNA sequences for P2RX6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for P2RX6
- Browse OriGene Inhibitory RNA Products For P2RX6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for P2RX6
- genomics-online: shRNA clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
Clone Products
- Sino Biological Human cDNA Clone for P2RX6
- Addgene plasmids for P2RX6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for P2RX6
- Applied Biological Materials Clones for P2RX6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for P2RX6 (P2X6/P2RX6)
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||||||||||||
| SP8: |
Expression for P2RX6 Gene
mRNA differential expression in normal tissues according to GTEx for P2RX6 Gene
This gene is overexpressed in Muscle - Skeletal (x14.5).
This gene is overexpressed in Plasma (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for P2RX6 Gene
NURSA nuclear receptor signaling pathways regulating expression of P2RX6 Gene:
P2RX6SOURCE GeneReport for Unigene cluster for P2RX6 Gene:
Hs.113275mRNA Expression by UniProt/SwissProt for P2RX6 Gene:
O15547-P2RX6_HUMAN
Tissue specificity:
Expressed predominantly in skeletal muscle.
Evidence on tissue expression from TISSUES for P2RX6 Gene
- Muscle(4.5)
- Nervous system(4.4)
- Heart(2)
Primer Products
-
OriGene qPCR primer pairs for P2RX6
-
OriGene qPCR primer pairs and template standards for P2RX6
- genomics-online: primer clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for P2RX6 Gene
Orthologs for P2RX6 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | P2RX6 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | P2rx6 16 34 33 |
|
||
| dog (Canis familiaris) |
Mammalia | P2RX6 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | P2rx6 33 |
|
||
| cow (Bos Taurus) |
Mammalia | P2RX6 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | P2RX6 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| chicken (Gallus gallus) |
Aves | LOC429367 33 |
|
||
| P2RX6 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | P2RX6 34 |
|
OneToOne |
- Species where no ortholog for P2RX6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for P2RX6 Gene
- ENSEMBL:
- Gene Tree for P2RX6 (if available)
- TreeFam:
- Gene Tree for P2RX6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for P2RX6: view image
Paralogs for P2RX6 Gene
(6) SIMAP similar genes for P2RX6 Gene using alignment to 7 proteins:
- P2RX6_HUMAN
- E7ES48_HUMAN
- H7C140_HUMAN
- H7C266_HUMAN
- H7C2V4_HUMAN
- Q05BG9_HUMAN
- Q6P1Z3_HUMAN
Pseudogenes.org Pseudogenes for P2RX6 Gene
Variants for P2RX6 Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000168107 | -- | 21,012,780(+) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000193781 | -- | 21,019,764(+) | G/C | intron_variant | |
| rs1000227427 | -- | 21,009,343(+) | C/T | upstream_transcript_variant | |
| rs1000476368 | -- | 21,014,262(+) | T/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000529205 | -- | 21,018,770(+) | G/A | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4483n100 | CNV | gain | 25217958 |
| dgv7993n54 | CNV | gain | 21841781 |
| dgv7994n54 | CNV | gain | 21841781 |
| esv2678175 | CNV | deletion | 23128226 |
| esv2763693 | CNV | gain | 21179565 |
| esv3647304 | CNV | loss | 21293372 |
| esv3647305 | CNV | gain | 21293372 |
| esv3647307 | CNV | loss | 21293372 |
| esv3647308 | CNV | loss | 21293372 |
| esv3893441 | CNV | gain+loss | 25118596 |
| nsv1056614 | CNV | loss | 25217958 |
| nsv1062280 | CNV | gain | 25217958 |
| nsv1065617 | CNV | gain | 25217958 |
| nsv3563 | CNV | deletion | 18451855 |
| nsv436864 | CNV | insertion | 17901297 |
| nsv471185 | CNV | loss | 18288195 |
| nsv523162 | CNV | loss | 19592680 |
| nsv588305 | CNV | loss | 21841781 |
| nsv588306 | CNV | gain | 21841781 |
| nsv828960 | CNV | loss | 20364138 |
| nsv828961 | CNV | gain | 20364138 |
| nsv834141 | CNV | loss | 17160897 |
| nsv834142 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
70.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.58;
65.13% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for P2RX6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- P2RX6
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for P2RX6 Gene
Disorders for P2RX6 Gene
Additional Disease Information for P2RX6
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for P2RX6 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for P2RX6 Gene
Publications for P2RX6 Gene
- Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes. (PMID: 18852390) Palomino-Doza J … Keavney B (Hypertension (Dallas, Tex. : 1979) 2008) 3 22 44 58
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 2 3 4 58
- Cloning of P2XM, a novel human P2X receptor gene regulated by p53. (PMID: 9242461) Urano T … Tokino T (Cancer research 1997) 2 3 4 58
- Gene variants associated with ischemic stroke: the cardiovascular health study. (PMID: 19023099) Luke MM … Psaty BM (Stroke 2009) 3 44 58
- Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G … Wijmenga C (Gut 2009) 3 44 58
Products for P2RX6 Gene
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- Taconic Biosciences Mouse Models for P2RX6
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for P2RX6 (AFLGC-P2RX6)
- Cyagen custom Knockout/knockin (KOKI) mouse models for P2RX6
- Addgene plasmids for P2RX6
- antibodies-online: Search results for 76 available P2RX6 Antibodies ranked by validation data
- Compare Top P2RX6 Antibodies
- antibodies-online: Search results for available P2RX6 related products ranked by validation data
- antibodies-online: Search results for 4 available P2RX6 Proteins ranked by validation data
- Compare Top P2RX6 Proteins
- Quality Products:
- GeneTex P2RX6 Antibody for P2RX6
- Search GeneTex for Proteins for P2RX6
- Santa Cruz Biotechnology (SCBT) Antibodies for P2RX6
- Search Santa Cruz Biotechnology (SCBT) for P2RX6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for P2RX6
- Horizon Cell Lines for P2RX6
- genomics-online: cdna clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- orf clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- genomics-online: gRNA clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- genomics-online: primer clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- genomics-online: shRNA clones - Search results for 104 available P2RX6 gene related products
- Overview of 104 available P2RX6 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for P2RX6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for P2RX6
- GeneCopoeia miRNA 3'UTR Target clone products for P2RX6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for P2RX6
- Boster Bio Antibodies for P2RX6
- Browse Boster Bio ELISA Kits
Sources for P2RX6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
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- (13) InterPro
- (14) ProtoNet
- (15) Blocks
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- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
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- (57) OriGene
- (58) PubMed
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- (60) TGDB
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- (63) Novus Biologicals
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- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
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- (84) Vector BioLabs
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- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
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- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
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- (108) SCBT
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
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- (155) genomics-online
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- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt