External Ids for OXTR Gene
Previous GeneCards Identifiers for OXTR Gene
The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
GeneCards Summary for OXTR Gene
OXTR (Oxytocin Receptor) is a Protein Coding gene. Diseases associated with OXTR include Prosopagnosia and Alexithymia. Among its related pathways are Signaling by GPCR and Oxytocin signaling pathway. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and peptide hormone binding. An important paralog of this gene is AVPR1B.
UniProtKB/Swiss-Prot Summary for OXTR Gene
Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Oxytocin receptors (OT) are G-protein-coupled receptors that mediate parturition and lactation. They are closely related to vasopressin receptors. Oxytocin receptors are coupled to Gq/11 proteins and are localized to the myoepithelial cells of the mammary gland.