Aliases for OVGP1 Gene
External Ids for OVGP1 Gene
Previous HGNC Symbols for OVGP1 Gene
Previous GeneCards Identifiers for OVGP1 Gene
This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]
GeneCards Summary for OVGP1 Gene
OVGP1 (Oviductal Glycoprotein 1) is a Protein Coding gene. Diseases associated with OVGP1 include Chronic Salpingitis and Taylor's Syndrome. Among its related pathways are Fertilization. Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and chitinase activity. An important paralog of this gene is CHIT1.
UniProtKB/Swiss-Prot Summary for OVGP1 Gene
Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.