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OVCH1 (Ovochymase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is PLG.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH12J029500 | Enhancer | 0.2 | Ensembl | 600.7 | -1.4 | -1408 | 0.2 | OVCH1 LOC105369714 TMTC1 | ||
GH12J029428 | Enhancer | 1 | Ensembl ENCODE | 10.4 | +70.8 | 70787 | 4.2 | CTCF TEAD4 JUND STAT3 PKNOX1 REST RAD21 SP1 TRIM22 GTF2E2 | ERGIC2 OVCH1 ENSG00000257176 piR-37670 OVCH1-AS1 RF00017-1119 | |
GH12J029536 | Enhancer | 0.7 | Ensembl ENCODE | 10.4 | -37.9 | -37869 | 1.2 | CEBPB FOS JUN JUND EP300 BHLHE40 STAT1 STAT3 MAFK MAFF | OVCH1 ENSG00000257456 lnc-OVCH1-2 TMTC1 | |
GH12J029516 | Enhancer | 0.6 | Ensembl | 0.4 | -17.0 | -17008 | 1 | PKNOX1 CEBPB FOS GABPA JUND FOSL1 EP300 CEBPG TBP MEIS2 | LOC105369714 OVCH1 TMTC1 | |
GH12J029553 | Enhancer | 0.8 | Ensembl ENCODE | 0.2 | -52.9 | -52908 | 1.6 | CTCF REST RAD21 SP1 TRIM22 RUNX3 ATF3 YY1 SMC3 ZBTB33 | TMTC1 ENSG00000257456 OVCH1 lnc-OVCH1-2 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004252 | serine-type endopeptidase activity | IEA | -- |
GO:0008233 | peptidase activity | IEA | -- |
GO:0008236 | serine-type peptidase activity | IEA | -- |
GO:0016787 | hydrolase activity | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006508 | proteolysis | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | OVCH1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | OVCH1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | OVCH1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | OVCH1 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | OVCH1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | ovch1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | zgc:55888 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG11836 31 |
|
ManyToMany | |
CG3355 31 |
|
ManyToMany | |||
CG4914 31 |
|
ManyToMany | |||
CG9294 31 |
|
ManyToMany | |||
CG18735 31 |
|
ManyToMany | |||
CG4613 31 |
|
ManyToMany | |||
CG6865 31 |
|
ManyToMany | |||
CG4386 31 |
|
ManyToMany | |||
CG9372 31 |
|
ManyToMany | |||
CG14642 31 |
|
ManyToMany | |||
CG11843 31 |
|
ManyToMany | |||
CG11842 31 |
|
ManyToMany | |||
CG3700 31 |
|
ManyToMany | |||
CG31728 31 |
|
ManyToMany | |||
CG1299 31 |
|
ManyToMany | |||
CG14892 31 |
|
ManyToMany | |||
CG4927 31 |
|
ManyToMany | |||
spirit 31 |
|
ManyToMany | |||
CG11841 31 |
|
ManyToMany | |||
psh 31 |
|
ManyToMany | |||
CG11670 31 |
|
ManyToMany | |||
snk 31 |
|
ManyToMany | |||
CG11668 31 |
|
ManyToMany | |||
CG32260 31 |
|
ManyToMany | |||
CG8172 31 |
|
ManyToMany | |||
CG7432 31 |
|
ManyToMany | |||
CG6361 31 |
|
ManyToMany | |||
Sb 31 |
|
ManyToMany | |||
CG34350 31 |
|
ManyToMany | |||
CG8213 31 |
|
ManyToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.6617 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs10843438 | - | p.Arg133Cys | |||
rs11050243 | - | p.Ser672Phe | |||
rs12305672 | - | p.Gly754Arg | |||
rs1347570 | - | p.Pro881Ala | |||
rs35183403 | - | p.Leu557Val |
No disorders were found for OVCH1 Gene.