OVAAL Gene (RNA Gene)

Ovarian Adenocarcinoma Amplified Long Non-Coding RNA

GC01P180558
GIFtS:
14
See more...

Aliases for OVAAL Gene

Subcategory (RNA class) for OVAAL Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for OVAAL Gene

  • Ovarian Adenocarcinoma Amplified Long Non-Coding RNA 2 3 5
  • OVAAL 2 5 165
  • Long Intergenic Non-Protein Coding RNA 1131 2 3
  • Ovarian Adenocarcinoma Amplified LncRNA 2 3
  • LINC01131 2 3
  • OVAL 2 3
  • NONHSAG003627.2 91
  • HSALNG0008819 164

External Ids for OVAAL Gene

Previous GeneCards Identifiers for OVAAL Gene

  • GC00U936048

Summaries for OVAAL Gene

GeneCards Summary for OVAAL Gene

OVAAL (Ovarian Adenocarcinoma Amplified Long Non-Coding RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with OVAAL include Ovarian Cancer and Ovary Adenocarcinoma.

Rfam classification for OVAAL Gene

Additional gene information for OVAAL Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for OVAAL Gene

Genomics for OVAAL Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for OVAAL Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J180507 Enhancer 0.9 Ensembl ENCODE 600.7 -1.2 -1159 1.3 CREB1 ARID3A JUND FOXA1 ATF7 CTCF CEBPB CTBP1 FOS ZNF316 OVAAL ACBD6 LHX4-AS1 XPR1
GH01J180558 Promoter 0.4 EPDnew 600.3 +49.6 49565 0.1 CHAMP1 OVAAL RF00004-008 HSALNG0008813 ACBD6 XPR1
GH01J180515 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 0.4 +6.9 6855 1.9 GATAD2A CTCF LEF1 JUND FOXA1 ZNF143 REST RAD21 IRF2 BRD9 XPR1 ENSG00000243155 KIAA1614 LINC02816 ACBD6 KY994054-002 OVAAL
GH01J180521 Enhancer 1 Ensembl ENCODE 0.4 +13.0 13044 2.5 CREB1 GATAD2A ATF7 TEAD4 TFE3 LEF1 IKZF1 JUND PKNOX1 RXRB XPR1 ACBD6 ENSG00000206905 MG828455 OVAAL
GH01J180533 Enhancer 1 Ensembl ENCODE 0.4 +24.3 24345 0.6 CTCF JUND ZNF143 PHF21A REST NR2C1 RAD21 IRF2 ZNF740 BRD9 MG828455 HSALNG0008813 OVAAL ACBD6 XPR1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OVAAL on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OVAAL Gene

Genomic Locations for OVAAL Gene
chr1:180,509,380-180,566,523
(GRCh38/hg38)
Size:
57,144 bases
Orientation:
Plus strand

Genomic View for OVAAL Gene

Genes around OVAAL on UCSC Golden Path with GeneCards custom track
OVAAL in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
OVAAL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OVAAL Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for OVAAL Gene

Proteins for OVAAL Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for OVAAL Gene

No Post-translational modifications

No data available for DME Specific Peptides for OVAAL Gene

Domains & Families for OVAAL Gene

Gene Families for OVAAL Gene

HGNC:
genes like me logo Genes that share domains with OVAAL: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for OVAAL Gene

Function for OVAAL Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for OVAAL Gene

Gene Ontology (GO) - Molecular Function for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045131 pre-mRNA branch point binding IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OVAAL Gene

Localization for OVAAL Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OVAAL gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
lysosome 1

Gene Ontology (GO) - Cellular Components for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005686 U2 snRNP IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for OVAAL Gene

Pathways & Interactions for OVAAL Gene

PathCards logo

SuperPathways for OVAAL Gene

No Data Available

Gene Ontology (GO) - Biological Process for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000348 mRNA branch site recognition IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for OVAAL Gene

Drugs & Compounds for OVAAL Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for OVAAL Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

Non-coding RNA (ncRNA) Transcripts from RNAcentral for OVAAL Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00003A78BB_9606 lncRNA 1489 3

Ensembl: ENST00000442621 (view in UCSC) ,

LncBook: HSALNT0018256,

LNCipedia: OVAAL:2,

URS00007E36BD_9606 lncRNA 1491 2

HGNC: 49422,

RefSeq: NR_125716,

URS000198FBC9_9606 lncRNA 1786 1

Ensembl: ENST00000673955 (view in UCSC) ,

URS0000EED322_9606 lncRNA 1589 1

Ensembl: ENST00000668742 (view in UCSC) ,

URS0000DB879B_9606 lncRNA 1524 1

Ensembl: ENST00000648175 (view in UCSC) ,

OVAAL in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for OVAAL Gene

5 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for OVAAL Gene

No ASD Table

Relevant External Links for OVAAL Gene

GeneLoc Exon Structure for
OVAAL

Expression for OVAAL Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OVAAL Gene

mRNA expression in normal human tissues for OVAAL Gene
mRNA expression by GTEx for OVAAL Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OVAAL

genes like me logo Genes that share expression patterns with OVAAL: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OVAAL Gene

Orthologs for OVAAL Gene

Evolution for OVAAL Gene

ENSEMBL:
Gene Tree for OVAAL (if available)
TreeFam:
Gene Tree for OVAAL (if available)

No data available for Orthologs for OVAAL Gene

Paralogs for OVAAL Gene

No data available for Paralogs for OVAAL Gene

Variants for OVAAL Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Additional dbSNP identifiers (rs#s) for OVAAL Gene

Structural Variations from Database of Genomic Variants (DGV) for OVAAL Gene

Variant ID Type Subtype PubMed ID
nsv1003359 CNV gain 25217958

Additional Variant Information for OVAAL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OVAAL

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for OVAAL Gene

Disorders for OVAAL Gene

MalaCards: The human disease database

(2) MalaCards diseases for OVAAL Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
ovarian cancer
  • ovarian cancer, somatic
ovary adenocarcinoma
  • adenocarcinoma of the ovary
- elite association - COSMIC cancer census association via MalaCards
Search OVAAL in MalaCards View complete list of genes associated with diseases

Additional Disease Information for OVAAL

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with OVAAL: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OVAAL Gene

Publications for OVAAL Gene

  1. Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. (PMID: 24265805) Akrami R … Larsson E (PloS one 2013) 2 3
  2. Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. (PMID: 30478051) Sang B … Wu M (Proceedings of the National Academy of Sciences of the United States of America 2018) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

ExternalLinks

View latest publications for OVAAL gene in Mastermind

Products for OVAAL Gene

Sources for OVAAL Gene