Aliases for OVAAL Gene

Subcategory (RNA class) for OVAAL Gene

lncRNA

Quality Score for this RNA gene is

15

Aliases for OVAAL Gene

  • Ovarian Adenocarcinoma Amplified Long Non-Coding RNA 2 3 5
  • Long Intergenic Non-Protein Coding RNA 1131 2 3
  • Ovarian Adenocarcinoma Amplified LncRNA 2 3
  • OVAAL 2 170
  • HSALNG0008819 169
  • NONHSAG003627 94
  • LINC01131 3
  • OVAL 3

External Ids for OVAAL Gene

Previous GeneCards Identifiers for OVAAL Gene

  • GC00U936048

Summaries for OVAAL Gene

GeneCards Summary for OVAAL Gene

OVAAL (Ovarian Adenocarcinoma Amplified Long Non-Coding RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with OVAAL include Ovarian Cancer and Ovary Adenocarcinoma.

Rfam classification for OVAAL Gene

Additional gene information for OVAAL Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for OVAAL Gene

Genomics for OVAAL Gene

GeneHancer (GH) Regulatory Elements for OVAAL Gene

Promoters and enhancers for OVAAL Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J180548 Enhancer 0.5 Ensembl 750.6 +1.6 1565 0.8 ZNF362 ZNF384 SP7 ZIC2 ZBTB8A PATZ1 ARNT EZH2 REST OVAAL LHX4 ACBD6 RF00004-008
GH01J180547 Enhancer 0.2 Ensembl 750.6 -0.2 -235 0.4 OVAAL XPR1 ACBD6 LHX4 HSALNG0008813
GH01J180560 Enhancer 1 Ensembl ENCODE 0.4 +14.7 14665 4.2 SMARCE1 L3MBTL2 ZKSCAN8 GTF2F1 ZFX MAFK BACH1 SMARCA4 ZNF639 TRIM24 TOR1AIP1 CEP350 XPR1 ACBD6 LHX4 RF00004-008 OVAAL
GH01J180552 Enhancer 0.5 Ensembl 0.6 +4.8 4765 0.4 MAFK ZNF316 NFE2 EHMT2 MAFG MAFF EMSY LHX4 OVAAL RF00004-008
GH01J180542 Enhancer 0.5 Ensembl 0.6 -4.7 -4736 1.4 ZIC2 PRDM10 RFX1 ZBTB20 SMAD5 HSALNG0008813 XPR1 ACBD6 LHX4 OVAAL
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OVAAL on UCSC Golden Path with GeneCards custom track

Genomic Locations for OVAAL Gene

Genomic Locations for OVAAL Gene
chr1:180,547,436-180,566,520
(GRCh38/hg38)
Size:
19,085 bases
Orientation:
Plus strand

Genomic View for OVAAL Gene

Genes around OVAAL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OVAAL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OVAAL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OVAAL Gene

Proteins for OVAAL Gene

Post-translational modifications for OVAAL Gene

No Post-translational modifications

No data available for DME Specific Peptides for OVAAL Gene

Domains & Families for OVAAL Gene

Gene Families for OVAAL Gene

genes like me logo Genes that share domains with OVAAL: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for OVAAL Gene

Function for OVAAL Gene

Phenotypes From GWAS Catalog for OVAAL Gene

Gene Ontology (GO) - Molecular Function for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045131 pre-mRNA branch point binding IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OVAAL Gene

Localization for OVAAL Gene

Gene Ontology (GO) - Cellular Components for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005686 U2 snRNP IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OVAAL Gene

Pathways & Interactions for OVAAL Gene

PathCards logo

SuperPathways for OVAAL Gene

No Data Available

Gene Ontology (GO) - Biological Process for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000348 mRNA branch site recognition IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Pathways by source and SIGNOR curated interactions for OVAAL Gene

Drugs & Compounds for OVAAL Gene

No Compound Related Data Available

Transcripts for OVAAL Gene

mRNA/cDNA for OVAAL Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(8) RNACentral transcripts :
(5) LncBook transcripts :
(4) LNCipedia transcripts :
(4) NONCODE transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for OVAAL Gene

No ASD Table

Relevant External Links for OVAAL Gene

GeneLoc Exon Structure for
OVAAL
ECgene alternative splicing isoforms for
OVAAL

Expression for OVAAL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OVAAL Gene

NURSA nuclear receptor signaling pathways regulating expression of OVAAL Gene:

OVAAL
genes like me logo Genes that share expression patterns with OVAAL: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OVAAL Gene

Orthologs for OVAAL Gene

Evolution for OVAAL Gene

ENSEMBL:
Gene Tree for OVAAL (if available)
TreeFam:
Gene Tree for OVAAL (if available)

No data available for Orthologs for OVAAL Gene

Paralogs for OVAAL Gene

No data available for Paralogs for OVAAL Gene

Variants for OVAAL Gene

Sequence variations from dbSNP and Humsavar for OVAAL Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000547516 -- 180,564,597(+) C/T intron_variant
rs1000642188 -- 180,564,990(+) T/C intron_variant
rs1000802880 -- 180,558,846(+) G/T upstream_transcript_variant
rs1001048778 -- 180,561,361(+) A/G intron_variant
rs1001076380 -- 180,561,658(+) C/A/G/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for OVAAL Gene

Variant ID Type Subtype PubMed ID
nsv1003359 CNV gain 25217958

Additional Variant Information for OVAAL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OVAAL

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OVAAL Gene

Disorders for OVAAL Gene

MalaCards: The human disease database

(2) MalaCards diseases for OVAAL Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
ovarian cancer
  • ovarian cancer, somatic
ovary adenocarcinoma
  • adenocarcinoma of the ovary
- elite association - COSMIC cancer census association via MalaCards
Search OVAAL in MalaCards View complete list of genes associated with diseases

Additional Disease Information for OVAAL

genes like me logo Genes that share disorders with OVAAL: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OVAAL Gene

Publications for OVAAL Gene

  1. Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. (PMID: 24265805) Akrami R … Larsson E (PloS one 2013) 2 3 56
  2. Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. (PMID: 30478051) Sang B … Wu M (Proceedings of the National Academy of Sciences of the United States of America 2018) 3 56
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 56

Products for OVAAL Gene

Sources for OVAAL Gene