Aliases for OVAAL Gene

Data sources for OVAAL Gene:

Subcategory (RNA class) for OVAAL Gene

lncRNA

Aliases for OVAAL Gene

External Ids for OVAAL Gene

Previous GeneCards Identifiers for OVAAL Gene

  • GC00U936048
  • GC01P180558

Summaries for OVAAL Gene

GeneCards Summary for OVAAL Gene

OVAAL (Ovarian Adenocarcinoma Amplified Long Non-Coding RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with OVAAL include Ovarian Cancer and Ovary Adenocarcinoma.

Rfam classification for OVAAL Gene

Additional gene information for OVAAL Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for OVAAL Gene

Genomics for OVAAL Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OVAAL Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J180507 Enhancer 0.9 Ensembl ENCODE 250.7 -1.2 -1159 1.3 ARID3A CUX1 CTCF NUFIP1 CTBP1 JUND ZNF316 FOSL1 HLTF SMARCE1 OVAAL ACBD6 LHX4-AS1 XPR1
GH01J180558 Promoter 0.4 EPDnew 250.3 +49.6 49565 0.1 CHAMP1 OVAAL HSALNG0008819 HSALNG0008818 HSALNG0008813 ACBD6 XPR1
GH01J180515 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 0.4 +6.9 6855 1.9 CEBPA DEK ZNF217 CTCF ELF1 CEBPB REST GTF2E2 ZNF511 VEZF1 XPR1 ENSG00000243155 KIAA1614 LINC02816 ACBD6 KY994054-002 OVAAL
GH01J180521 Enhancer 0.9 ENCODE 0.4 +13.0 13044 2.5 CEBPA IKZF1 HOMEZ CEBPB RAD51 FOXA2 MAX SMAD4 SAP130 EP300 XPR1 ACBD6 ENSG00000206905 HSALNG0008816 OVAAL HSALNG0008813
GH01J180533 Enhancer 1 Ensembl ENCODE 0.3 +24.3 24345 0.6 TBP IRF2 ZNF217 CTCF REST ZNF740 VEZF1 NBN TRIM22 ZEB2 HSALNG0008816 HSALNG0008817 OVAAL ACBD6 HSALNG0008813 XPR1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OVAAL on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OVAAL Gene

Latest Assembly
chr1:180,509,380-180,571,450
(GRCh38/hg38)
Size:
62,071 bases
Orientation:
Plus strand

Previous Assembly
chr1:180,528,110-180,535,654
(GRCh37/hg19 by Entrez Gene)
Size:
7,545 bases
Orientation:
Plus strand

chr1:180,528,112-180,535,654
(GRCh37/hg19 by Ensembl)
Size:
7,543 bases
Orientation:
Plus strand

Genomic View for OVAAL Gene

Genes around OVAAL on UCSC Golden Path with GeneCards custom track
OVAAL in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
OVAAL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OVAAL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OVAAL Gene

Proteins for OVAAL Gene

Post-translational modifications for OVAAL Gene

No Post-translational modifications

No data available for DME Specific Peptides for OVAAL Gene

Domains & Families for OVAAL Gene

Gene Families for OVAAL Gene

genes like me logo Genes that share domains with OVAAL: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for OVAAL Gene

Function for OVAAL Gene

Phenotypes From GWAS Catalog for OVAAL Gene

Gene Ontology (GO) - Molecular Function for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045131 pre-mRNA branch point binding IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OVAAL Gene

Localization for OVAAL Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OVAAL gene
Compartment Confidence
nucleus 1
lysosome 1

Gene Ontology (GO) - Cellular Components for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005686 U2 snRNP IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for OVAAL Gene

Pathways & Interactions for OVAAL Gene

PathCards logo

SuperPathways for OVAAL Gene

No Data Available

Gene Ontology (GO) - Biological Process for OVAAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000348 mRNA branch site recognition IEA --
genes like me logo Genes that share ontologies with OVAAL: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for OVAAL Gene

Drugs & Compounds for OVAAL Gene

No Compound Related Data Available

Transcripts for OVAAL Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for OVAAL Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00003A78BB_9606 lncRNA 1492 3

Ensembl: ENST00000442621 (view in UCSC) ,

LncBook: HSALNT0018256,

LNCipedia: OVAAL:2,

URS000198FBC9_9606 lncRNA 1786 1

Ensembl: ENST00000673955 (view in UCSC) ,

URS0000EED322_9606 lncRNA 1589 1

Ensembl: ENST00000668742 (view in UCSC) ,

URS0000DB879B_9606 lncRNA 1524 1

Ensembl: ENST00000648175 (view in UCSC) ,

URS00007E36BD_9606 lncRNA 1491 1

RefSeq: NR_125716,

OVAAL in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for OVAAL Gene

5 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for OVAAL Gene

No ASD Table

Relevant External Links for OVAAL Gene

GeneLoc Exon Structure for
OVAAL

Expression for OVAAL Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OVAAL Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OVAAL

genes like me logo Genes that share expression patterns with OVAAL: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OVAAL Gene

Orthologs for OVAAL Gene

Evolution for OVAAL Gene

ENSEMBL:
Gene Tree for OVAAL (if available)
TreeFam:
Gene Tree for OVAAL (if available)

No data available for Orthologs for OVAAL Gene

Paralogs for OVAAL Gene

No data available for Paralogs for OVAAL Gene

Variants for OVAAL Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for OVAAL Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for OVAAL Gene

Variant ID Type Subtype PubMed ID
nsv1003359 CNV gain 25217958

Additional Variant Information for OVAAL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OVAAL

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for OVAAL Gene

Disorders for OVAAL Gene

MalaCards: The human disease database

(2) MalaCards diseases for OVAAL Gene - From: LNC and COP

Disorder Aliases PubMed IDs
ovarian cancer
  • ovarian cancer, somatic
ovary adenocarcinoma
  • adenocarcinoma of the ovary
- elite association - COSMIC cancer census association via MalaCards
Search OVAAL in MalaCards View complete list of genes associated with diseases

Additional Disease Information for OVAAL

genes like me logo Genes that share disorders with OVAAL: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OVAAL Gene

Publications for OVAAL Gene

  1. Comprehensive analysis of long non-coding RNAs in ovarian cancer reveals global patterns and targeted DNA amplification. (PMID: 24265805) Akrami R … Larsson E (PloS one 2013) 2 3 74
  2. Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. (PMID: 30478051) Sang B … Wu M (Proceedings of the National Academy of Sciences of the United States of America 2018) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for OVAAL Gene

Sources for OVAAL Gene