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This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011] See more...
Aliases for OTUB2 Gene
Aliases for OTUB2 Gene
- OTU Deubiquitinase, Ubiquitin Aldehyde Binding 2 2 3 5
- OTU Domain-Containing Ubiquitin Aldehyde-Binding Protein 2 3 4
- Ubiquitin-Specific-Processing Protease OTUB2 3 4
- OTU Domain, Ubiquitin Aldehyde Binding 2 2 3
- Deubiquitinating Enzyme OTUB2 3 4
- Ubiquitin Thioesterase OTUB2 3 4
- C14orf137 3 4
- Otubain-2 3 4
External Ids for OTUB2 Gene
- HGNC: 20351
- NCBI Entrez Gene: 78990
- Ensembl: ENSG00000089723
- OMIM®: 608338
- UniProtKB/Swiss-Prot: Q96DC9
Previous HGNC Symbols for OTUB2 Gene
- C14orf137
Previous GeneCards Identifiers for OTUB2 Gene
- GC14P092483
- GC14P093562
- GC14P094492
- GC14P074672
Summaries for OTUB2 Gene
-
This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. [provided by RefSeq, Aug 2011]
GeneCards Summary for OTUB2 Gene
OTUB2 (OTU Deubiquitinase, Ubiquitin Aldehyde Binding 2) is a Protein Coding gene. Among its related pathways are Protein ubiquitination and Deubiquitination. Gene Ontology (GO) annotations related to this gene include hydrolase activity and omega peptidase activity. An important paralog of this gene is OTUB1.
UniProtKB/Swiss-Prot Summary for OTUB2 Gene
-
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
Additional gene information for OTUB2 Gene
- HGNC (20351)
- NCBI Entrez Gene (78990)
- Ensembl (ENSG00000089723)
- OMIM® (608338)
- UniProtKB/Swiss-Prot (Q96DC9)
- Open Targets Platform(ENSG00000089723)
- Alliance of Genome Resources
- Search for OTUB2 at DataMed
- Search for OTUB2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OTUB2 Gene
Genomics for OTUB2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OTUB2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OTUB2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OTUB2
- Top Transcription factor binding sites by QIAGEN in the OTUB2 gene promoter:
-
- ATF
- ATF-2
- c-Jun
- HNF-1
- Lhx3a
- LHX3b
- p53
- POU2F1
- POU2F1a
- POU6F1 (c2)
Genomic Locations for OTUB2 Gene
Latest Assembly
- chr14:94,026,340-94,048,930
- (GRCh38/hg38)
- Size:
- 22,591 bases
- Orientation:
- Plus strand
Previous Assembly
- chr14:94,492,686-94,515,276
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 22,591 bases
- Orientation:
- Plus strand
Alternative Locations (GRCh38/hg38)
- chr14(ALT_REF_LOCI_1):1,140,902-1,163,492 (+)
Genomic View for OTUB2 Gene
Genes around OTUB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.12 by HGNC
- 14q32.12 by Entrez Gene
- 14q32.12 by Ensembl
OTUB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OTUB2 Gene
Proteins for OTUB2 Gene
-
Protein details for OTUB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96DC9-OTUB2_HUMAN
- Recommended name:
- Ubiquitin thioesterase OTUB2
- Protein Accession:
- Q96DC9
- Q6IA10
- Q9H6T1
Protein attributes for OTUB2 Gene
- Size:
- 234 amino acids
- Molecular mass:
- 27213 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- In the structure described by PubMed:15258613, the Asp-48 active site of the catalytic triad is located too far to interact directly with the active site His-224. A possible explanation is that OTUB2 is in inactive conformation in absence of ubiquitin and a conformation change may move Asp-48 in the proximity of His-224 in presence of ubiquitin substrate.
Three dimensional structures from OCA and Proteopedia for OTUB2 Gene
Protein Expression for OTUB2 Gene
Post-translational modifications for OTUB2 Gene
Other Protein References for OTUB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences OTUB2 Antibody
- G Biosciences Immunotag™ OTUB2 Antibody
-
Custom Antibody ServicesOriGene Antibodies for OTUB2
- Novus Biologicals Antibodies for OTUB2
-
Abcam antibodies for OTUB2
- Invitrogen Antibodies for OTUB2 (AFLGC-OTUB2)
-
Biorbyt antibodies for OTUB2
- Sino Biological Antibodies for OTUB2
Protein products for research
- G Biosciences Human Ubiquitin Thioesterase Otub2/Otub2, Liquid
- Search Origene for MassSpec and Protein Over-expression Lysates for OTUB2
- Origene Custom Protein Services for OTUB2
- Sino Biological Recombinant Proteins for OTUB2
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for OTUB2
- antibodies-online: Show 11 available OTUB2 Proteins ranked by validation data
- Compare Top OTUB2 Proteins
-
Quality Products:
-
ProSci Proteins for OTUB2
-
Abcam proteins for OTUB2
Assay products for research
- antibodies-online: Show 1 available OTUB2 Elisa Kits ranked by validation data
- Compare Top OTUB2 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for OTUB2 Gene
Domains & Families for OTUB2 Gene
Gene Families for OTUB2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for OTUB2 Gene
Suggested Antigen Peptide Sequences for OTUB2 Gene
- GenScript: Design optimal peptide antigens:
-
- Ubiquitin-specific-processing protease OTUB2 (OTUB2_HUMAN)
- OTUB2 protein (Q9BWI9_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96DC9- Family:
-
- Belongs to the peptidase C65 family.
Function for OTUB2 Gene
Molecular function for OTUB2 Gene
- UniProtKB/Swiss-Prot Function:
- Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).; EC=3.4.19.12; Evidence={ECO:0000269|PubMed:23827681};.
Enzyme Numbers (IUBMB) for OTUB2 Gene
Phenotypes From GWAS Catalog for OTUB2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IBA,IMP | 15258613 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008233 | peptidase activity | IEA | -- |
| GO:0008234 | cysteine-type peptidase activity | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for OTUB2 Gene
- GenomeRNAi human phenotypes for OTUB2:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for OTUB2 - Starting at $85 >
- * OTUB2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for OTUB2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OTUB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OTUB2
miRNA for OTUB2 Gene
- miRTarBase miRNAs that target OTUB2
-
- hsa-miR-335-5p (MIRT016886)
- hsa-miR-215-5p (MIRT024538)
- hsa-miR-192-5p (MIRT026192)
- hsa-miR-125a-5p (MIRT045773)
- hsa-miR-5687 (MIRT495369)
- hsa-miR-6769a-3p (MIRT495370)
- hsa-miR-3186-5p (MIRT495371)
- hsa-miR-4773 (MIRT495372)
- hsa-miR-6856-3p (MIRT495373)
- hsa-miR-4420 (MIRT535550)
- hsa-miR-181b-3p (MIRT535551)
- hsa-miR-181b-2-3p (MIRT535552)
- hsa-miR-4313 (MIRT535553)
- hsa-miR-4424 (MIRT535554)
- hsa-miR-4682 (MIRT535555)
- hsa-miR-1304-3p (MIRT535556)
- hsa-miR-6887-3p (MIRT535557)
- hsa-miR-3943 (MIRT535558)
- hsa-miR-3680-5p (MIRT535559)
- hsa-miR-4279 (MIRT638481)
- hsa-miR-629-3p (MIRT638482)
- hsa-miR-1264 (MIRT638483)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OTUB2
- Browse OriGene Inhibitory RNA Products For OTUB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OTUB2
Clone products for research
- Applied Biological Materials (abm): Clones for OTUB2 - Starting at $45 >
- * OTUB2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for OTUB2
- Addgene plasmids for OTUB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OTUB2
Cell Lines for research
-
Horizon Cell Lines for OTUB2
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OTUB2 Gene
Localization for OTUB2 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytoskeleton | 3 |
| cytosol | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for OTUB2 Gene
Pathways & Interactions for OTUB2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Protein ubiquitination | ||
| 3 | Deubiquitination |
.74
|
|
| 4 | Ovarian tumor domain proteases | ||
Pathways by source for OTUB2 Gene
4 Reactome pathways for OTUB2 Gene
1 R&D Systems pathway for OTUB2 Gene
Interacting Proteins for OTUB2 Gene
Selected Interacting proteins:
Q96DC9-OTUB2_HUMAN
ENSP00000203664
for OTUB2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for OTUB2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA | -- |
| GO:0016579 | protein deubiquitination | IMP | 15258613 |
| GO:0018215 | protein phosphopantetheinylation | IEA | -- |
| GO:0035871 | protein K11-linked deubiquitination | IBA,IDA | 23827681 |
| GO:0070536 | protein K63-linked deubiquitination | IBA,IDA | 18954305 |
No data available for SIGNOR curated interactions for OTUB2 Gene
Drugs & Compounds for OTUB2 Gene
No Compound Related Data Available
Drug products for research
- G Biosciences Human Ubiquitin Thioesterase Otub2/Otub2, Liquid
Transcripts for OTUB2 Gene
mRNA/cDNA for OTUB2 Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000203664 3911 nts (view in UCSC)
- ENST00000553723 708 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for OTUB2 - Starting at $85 >
- * OTUB2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for OTUB2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OTUB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OTUB2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OTUB2
- Browse OriGene Inhibitory RNA Products For OTUB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OTUB2
Clone products for research
- Applied Biological Materials (abm): Clones for OTUB2 - Starting at $45 >
- * OTUB2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for OTUB2
- Addgene plasmids for OTUB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OTUB2
Relevant External Links for OTUB2 Gene
- GeneLoc Exon Structure for
- OTUB2
Expression for OTUB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for OTUB2 Gene
This gene is overexpressed in Testis (x10.3), Skin - Sun Exposed (Lower leg) (x6.9), and Skin - Not Sun Exposed (Suprapubic) (x5.5).
This gene is overexpressed in Ovary (34.6) and Testis (32.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for OTUB2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OTUB2
SOURCE GeneReport for Unigene cluster for OTUB2 Gene:
Hs.278815mRNA Expression by UniProt/SwissProt for OTUB2 Gene:
Q96DC9-OTUB2_HUMAN
Tissue specificity:
Widely expressed. Expressed at higher level in brain.
Evidence on tissue expression from TISSUES for OTUB2 Gene
- Lung(4.1)
- Eye(4)
Primer products for research
-
OriGene qPCR primer pairs for OTUB2
-
OriGene qPCR primer pairs and template standards for OTUB2
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for OTUB2 Gene
Orthologs for OTUB2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | OTUB2 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | OTUB2 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Otub2 29 16 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | OTUB2 29 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Otub2 29 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | OTUB2 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | OTUB2 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | otub2 29 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG4968 30 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | otub-1 30 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.5787 30 |
|
OneToMany |
- Species where no ortholog for OTUB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Zebrafish (Danio rerio)
Evolution for OTUB2 Gene
- ENSEMBL:
- Gene Tree for OTUB2 (if available)
- TreeFam:
- Gene Tree for OTUB2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for OTUB2: view image
- Alliance of Genome Resources:
- Additional Orthologs for OTUB2
Paralogs for OTUB2 Gene
(2) SIMAP similar genes for OTUB2 Gene using alignment to 3 proteins:
- OTUB2_HUMAN
- Q8WYS4_HUMAN
- Q9BWI9_HUMAN
Variants for OTUB2 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv34067 | CNV | loss | 18971310 |
| esv3581391 | CNV | loss | 25503493 |
| esv3635373 | CNV | gain | 21293372 |
| nsv565620 | CNV | loss | 21841781 |
| nsv952233 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
68% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.69;
46.15% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OTUB2 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OTUB2 Gene
Disorders for OTUB2 Gene
Additional Disease Information for OTUB2
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for OTUB2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OTUB2 Gene
Publications for OTUB2 Gene
- Otubains: a new family of cysteine proteases in the ubiquitin pathway. (PMID: 12704427) Balakirev MY … Chroboczek J (EMBO reports 2003) 2 3 4 22
- Crystal structure of human otubain 2. (PMID: 15258613) Nanao MH … Balakirev MY (EMBO reports 2004) 3 4 22
- OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. (PMID: 23827681) Mevissen TE … Komander D (Cell 2013) 3 4
- Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. (PMID: 19996094) Li S … Shu HB (The Journal of biological chemistry 2010) 2 3
- Structural basis and specificity of human otubain 1-mediated deubiquitination. (PMID: 18954305) Edelmann MJ … Kessler BM (The Biochemical journal 2009) 3 4
ExternalLinks
Products for OTUB2 Gene
- Custom Antibody ServicesOriGene Antibodies for OTUB2
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for OTUB2
- Origene Custom Protein Services for OTUB2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OTUB2
- Browse OriGene Inhibitory RNA Products For OTUB2
- OriGene qPCR primer pairs for OTUB2
- OriGene qPCR primer pairs and template standards for OTUB2
- OriGene CRISPR knockouts for OTUB2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For OTUB2
- Sino Biological Human cDNA Clone for OTUB2
- Sino Biological Recombinant Proteins for OTUB2
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for OTUB2
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for OTUB2
- Novus Biologicals proteins and lysates for OTUB2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for OTUB2
- Abcam proteins for OTUB2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for OTUB2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OTUB2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OTUB2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OTUB2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OTUB2
- Addgene plasmids for OTUB2
- antibodies-online: Show 34 available OTUB2 Antibodies ranked by validation data
- Compare Top OTUB2 Antibodies
- antibodies-online: Show 1 available OTUB2 Elisa Kits ranked by validation data
- Compare Top OTUB2 Elisa Kits
- Quality Products:
- antibodies-online: Show 11 available OTUB2 Proteins ranked by validation data
- Compare Top OTUB2 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for OTUB2
- ProSci Proteins for OTUB2
- Horizon Cell Lines for OTUB2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OTUB2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OTUB2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OTUB2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OTUB2
- Biorbyt antibodies for OTUB2
Sources for OTUB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
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- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
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- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources