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Aliases for OTOP2 Gene
External Ids for OTOP2 Gene
- HGNC: 19657
- Entrez Gene: 92736
- Ensembl: ENSG00000183034
- OMIM: 607827
- UniProtKB: Q7RTS6
Previous GeneCards Identifiers for OTOP2 Gene
- GC17P073384
- GC17P073517
- GC17P070431
- GC17P072922
- GC17P068330
Summaries for OTOP2 Gene
GeneCards Summary for OTOP2 Gene
OTOP2 (Otopetrin 2) is a Protein Coding gene. Diseases associated with OTOP2 include Usher Syndrome and Colorectal Cancer. An important paralog of this gene is OTOP3.
UniProtKB/Swiss-Prot Summary for OTOP2 Gene
-
Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.
Additional gene information for OTOP2 Gene
- HGNC(19657)
- Entrez Gene(92736)
- Ensembl(ENSG00000183034)
- OMIM(607827)
- UniProtKB(Q7RTS6)
- Open Targets Platform(ENSG00000183034)
- Search for OTOP2 at DataMed
- Search for OTOP2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OTOP2 Gene
Genomics for OTOP2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OTOP2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH17J074926 | Promoter | 1.3 | EPDnew Ensembl | 600.7 | +0.3 | 251 | 0.4 | PRDM10 ZNF143 PATZ1 CTCF EZH2 HDAC1 ZNF561 SCRT2 ZBTB44 KLF9 | OTOP2 USH1G | |
| GH17J074923 | Promoter/Enhancer | 1.2 | Ensembl ENCODE | 600.7 | +0.8 | 751 | 0.2 | GATAD2A CTCF PRDM10 TFE3 REST RAD21 IRF2 EZH2 HDAC1 ZNF561 | OTOP2 USH1G OTOP3 | |
| GH17J074920 | Enhancer | 0.7 | Ensembl | 600.7 | -1.7 | -1650 | 1.4 | ZNF692 ZIC2 PATZ1 SCRT2 ZBTB20 SCRT1 WT1 ZFHX2 ZFP69B ZNF18 | OTOP2 USH1G piR-33422-180 FADS6 | |
| GH17J074925 | Promoter | 0.6 | EPDnew | 600.7 | +1.3 | 1333 | 0.1 | IKZF1 PKNOX1 EZH2 TFDP1 MEIS2 ZBTB8A | OTOP2 USH1G OTOP3 | |
| GH17J074924 | Promoter | 0.6 | EPDnew | 600.7 | +1.7 | 1700 | 0.1 | IKZF1 POLR2A EZH2 | OTOP2 USH1G OTOP3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OTOP2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OTOP2
- Top Transcription factor binding sites by QIAGEN in the OTOP2 gene promoter:
-
- C/EBPalpha
- CHOP-10
- CREB
- deltaCREB
- FOXO1
- FOXO1a
- Hlf
- Nkx5-1
- Pax-4a
- ZID
Genomic Locations for OTOP2 Gene
Genomic Locations for OTOP2 Gene
- chr17:74,922,950-74,933,913
- (GRCh38/hg38)
- Size:
- 10,964 bases
- Orientation:
- Plus strand
- chr17:72,920,370-72,930,007
- (GRCh37/hg19)
- Size:
- 9,638 bases
- Orientation:
- Plus strand
Genomic View for OTOP2 Gene
Genes around OTOP2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by HGNC
- 17q25.1 by Entrez Gene
- 17q25.1 by Ensembl
OTOP2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OTOP2 Gene
Proteins for OTOP2 Gene
-
Protein details for OTOP2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7RTS6-OTOP2_HUMAN
- Recommended name:
- Proton channel OTOP2
- Protein Accession:
- Q7RTS6
Protein attributes for OTOP2 Gene
- Size:
- 562 amino acids
- Molecular mass:
- 62236 Da
- Quaternary structure:
- No Data Available
Protein Expression for OTOP2 Gene
Post-translational modifications for OTOP2 Gene
Other Protein References for OTOP2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for OTOP2
-
Abcam antibodies for OTOP2
- Invitrogen Antibodies for OTOP2 (AFLGC-OTOP2)
- antibodies-online: Show 9 available Otopetrin 2 Antibodies ranked by validation data
Protein Products
-
OriGene Purified Proteins for OTOP2
- Search Origene for MassSpec and Protein Over-expression Lysates for OTOP2
- Origene Custom Protein Services for OTOP2
-
Abcam proteins for OTOP2
No data available for DME Specific Peptides for OTOP2 Gene
Domains & Families for OTOP2 Gene
Gene Families for OTOP2 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
Suggested Antigen Peptide Sequences for OTOP2 Gene
- GenScript: Design optimal peptide antigens:
-
- Otopetrin-2 (OTOP2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q7RTS6- Family:
-
- Belongs to the otopetrin family.
Function for OTOP2 Gene
Molecular function for OTOP2 Gene
- UniProtKB/Swiss-Prot Function:
- Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.
Phenotypes From GWAS Catalog for OTOP2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0015252 | proton channel activity | IEA,ISS | -- |
Phenotypes for OTOP2 Gene
- MGI mutant phenotypes for OTOP2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for OTOP2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OTOP2 - Select products 50% OFF >
- * OTOP2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OTOP2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OTOP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OTOP2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OTOP2
- Browse OriGene Inhibitory RNA Products For OTOP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OTOP2
Clone Products
- Applied Biological Materials (abm): Clones for OTOP2 - Select products 50% OFF >
- * OTOP2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OTOP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OTOP2
Cell Line Products
-
Horizon Cell Lines for OTOP2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OTOP2 Gene
Localization for OTOP2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OTOP2 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| extracellular | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for OTOP2 Gene
Pathways & Interactions for OTOP2 Gene
Interacting Proteins for OTOP2 Gene
Selected Interacting proteins:
Q7RTS6-OTOP2_HUMAN
ENSP00000332528
for OTOP2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for OTOP2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006811 | ion transport | IEA | -- |
| GO:1902600 | proton transmembrane transport | IEA,ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for OTOP2 Gene
Transcripts for OTOP2 Gene
mRNA/cDNA for OTOP2 Gene
- 1 REFSEQ mRNAs :
- 2 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000331427 2150 nts (view in UCSC)
- ENST00000580223 1303 nts (view in UCSC)
- ENST00000584711 1365 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OTOP2 - Select products 50% OFF >
- * OTOP2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OTOP2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OTOP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OTOP2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OTOP2
- Browse OriGene Inhibitory RNA Products For OTOP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OTOP2
Clone Products
- Applied Biological Materials (abm): Clones for OTOP2 - Select products 50% OFF >
- * OTOP2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OTOP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OTOP2
Relevant External Links for OTOP2 Gene
- GeneLoc Exon Structure for
- OTOP2
Expression for OTOP2 Gene
mRNA differential expression in normal tissues according to GTEx for OTOP2 Gene
This gene is overexpressed in Colon - Transverse (x35.4) and Testis (x8.4).
This gene is overexpressed in Platelet (54.9) and Placenta (14.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OTOP2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OTOP2
SOURCE GeneReport for Unigene cluster for OTOP2 Gene:
Hs.352515Primer Products
-
OriGene qPCR primer pairs for OTOP2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OTOP2 Gene
Orthologs for OTOP2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | OTOP2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | OTOP2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | OTOP2 30 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | Otop2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Otop2 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | OTOP2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | OTOP2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | OTOP2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | OTOP2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100496174 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | otop2 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG42265 30 |
|
- Species where no ortholog for OTOP2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for OTOP2 Gene
- ENSEMBL:
- Gene Tree for OTOP2 (if available)
- TreeFam:
- Gene Tree for OTOP2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for OTOP2: view image
Paralogs for OTOP2 Gene
Variants for OTOP2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OTOP2 Gene
| SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 773069 | Benign: not provided | 74,930,587(+) | G/A | MISSENSE_VARIANT | |
| 778747 | Benign: not provided | 74,933,421(+) | C/G | MISSENSE_VARIANT | |
| 805739 | Uncertain Significance: not provided | 74,923,009(+) | C/T | MISSENSE_VARIANT,FIVE_PRIME_UTR_VARIANT | |
| 891906 | Uncertain Significance: Usher syndrome, type 1G | 74,923,149(+) | T/C | FIVE_PRIME_UTR_VARIANT | |
| rs104894652 | Pathogenic: Usher syndrome, type 1G | 74,922,961(+) | C/T | NONSENSE,FIVE_PRIME_UTR_VARIANT |
Residual Variation Intolerance Score:
33.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.32;
53.49% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OTOP2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- OTOP2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OTOP2 Gene
Disorders for OTOP2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| usher syndrome |
|
|
| colorectal cancer |
|
|
Search OTOP2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for OTOP2
No data available for UniProtKB/Swiss-Prot and Genatlas for OTOP2 Gene
Publications for OTOP2 Gene
- Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. (PMID: 12651873) Hurle B … Ornitz DM (Human molecular genetics 2003) 2 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- Wild-type p53 regulates OTOP2 transcription through DNA loop alteration of the promoter in colorectal cancer. (PMID: 30652071) Qu H … Xin C (FEBS open bio 2019) 3
- The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjöblom T … Velculescu VE (Science (New York, N.Y.) 2006) 4
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4
ExternalLinks
Products for OTOP2 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for OTOP2
- Search Origene for MassSpec and Protein Over-expression Lysates for OTOP2
- Origene Custom Protein Services for OTOP2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OTOP2
- Browse OriGene Inhibitory RNA Products For OTOP2
- OriGene qPCR primer pairs for OTOP2
- OriGene CRISPR knockouts for OTOP2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For OTOP2
- Sino Biological Human cDNA Clone for OTOP2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for OTOP2
- Novus Biologicals proteins and lysates for OTOP2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for OTOP2
- Abcam proteins for OTOP2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for OTOP2 (AFLGC-OTOP2)
- VectorBuilder Custom and pre-made DNA vectors for OTOP2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OTOP2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OTOP2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OTOP2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OTOP2
- antibodies-online: Show 9 available Otopetrin 2 Antibodies ranked by validation data
- antibodies-online: Search results for available Otopetrin 2 related products ranked by validation data
- antibodies-online: Search results for available Otopetrin 2 related products ranked by validation data
- Horizon Cell Lines for OTOP2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OTOP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OTOP2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OTOP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OTOP2
Sources for OTOP2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB