Aliases for OSTF1 Gene
External Ids for OSTF1 Gene
Previous GeneCards Identifiers for OSTF1 Gene
Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008]
GeneCards Summary for OSTF1 Gene
OSTF1 (Osteoclast Stimulating Factor 1) is a Protein Coding gene. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include SH3 domain binding. An important paralog of this gene is ANKRD27.
UniProtKB/Swiss-Prot for OSTF1 Gene
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.