Aliases for OSTC Gene
External Ids for OSTC Gene
Previous GeneCards Identifiers for OSTC Gene
GeneCards Summary for OSTC Gene
OSTC (Oligosaccharyltransferase Complex Non-Catalytic Subunit) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include dolichyl-diphosphooligosaccharide-protein glycotransferase activity.
UniProtKB/Swiss-Prot for OSTC Gene
May act as substrate-specific component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.