Aliases for OSBPL11 Gene
External Ids for OSBPL11 Gene
Previous GeneCards Identifiers for OSBPL11 Gene
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008]
GeneCards Summary for OSBPL11 Gene
OSBPL11 (Oxysterol Binding Protein Like 11) is a Protein Coding gene. Diseases associated with OSBPL11 include Wernicke-Korsakoff Syndrome and Thiamine Deficiency Disease. Gene Ontology (GO) annotations related to this gene include lipid binding. An important paralog of this gene is OSBPL10.
UniProtKB/Swiss-Prot Summary for OSBPL11 Gene
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193).