Aliases for ORM1 Gene
External Ids for ORM1 Gene
Previous GeneCards Identifiers for ORM1 Gene
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]
GeneCards Summary for ORM1 Gene
ORM1 (Orosomucoid 1) is a Protein Coding gene. Diseases associated with ORM1 include Dry Eye Syndrome and Appendicitis. Among its related pathways are Innate Immune System and Carvedilol Pathway, Pharmacokinetics. An important paralog of this gene is ORM2.
UniProtKB/Swiss-Prot Summary for ORM1 Gene
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.