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Aliases for ORAI3 Gene
Aliases for ORAI3 Gene
External Ids for ORAI3 Gene
- HGNC: 28185
- Entrez Gene: 93129
- Ensembl: ENSG00000175938
- OMIM: 610930
- UniProtKB: Q9BRQ5
Previous HGNC Symbols for ORAI3 Gene
- TMEM142C
Previous GeneCards Identifiers for ORAI3 Gene
- GC16P030869
- GC16P030870
- GC16P030960
- GC16P028524
Summaries for ORAI3 Gene
GeneCards Summary for ORAI3 Gene
ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3) is a Protein Coding gene. Diseases associated with ORAI3 include Estrogen-Receptor Negative Breast Cancer and Myopathy, Tubular Aggregate, 1. Among its related pathways are Calcium signaling pathway and B Cell Receptor Signaling Pathway (sino). Gene Ontology (GO) annotations related to this gene include store-operated calcium channel activity. An important paralog of this gene is ORAI1.
UniProtKB/Swiss-Prot Summary for ORAI3 Gene
-
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
-
STIM-Orai channels have recently been identified as the underlying molecular mechanism of store-operated calcium entry (SOCE). STIM (stromal interaction molecule) proteins are ER Ca2+ sensors. Orai proteins are STIM binding partners that form the channel pore.
Additional gene information for ORAI3 Gene
- HGNC(28185)
- Entrez Gene(93129)
- Ensembl(ENSG00000175938)
- OMIM(610930)
- UniProtKB(Q9BRQ5)
- Open Targets Platform(ENSG00000175938)
- Search for ORAI3 at DataMed
- Search for ORAI3 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for ORAI3 Gene
Genomics for ORAI3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for ORAI3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around ORAI3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for ORAI3
- Top Transcription factor binding sites by QIAGEN in the ORAI3 gene promoter:
-
- AREB6
- Arnt
- c-Rel
- CREB
- HTF
- LCR-F1
- MZF-1
- NF-1
- NF-1/L
- NF-AT
Genomic Locations for ORAI3 Gene
Genomic Locations for ORAI3 Gene
- chr16:30,949,068-30,956,461
- (GRCh38/hg38)
- Size:
- 7,394 bases
- Orientation:
- Plus strand
- chr16:30,960,387-30,967,782
- (GRCh37/hg19)
- Size:
- 7,396 bases
- Orientation:
- Plus strand
Genomic View for ORAI3 Gene
Genes around ORAI3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
ORAI3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ORAI3 Gene
Proteins for ORAI3 Gene
-
Protein details for ORAI3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9BRQ5-ORAI3_HUMAN
- Recommended name:
- Protein orai-3
- Protein Accession:
- Q9BRQ5
- Q96BI8
Protein attributes for ORAI3 Gene
- Size:
- 295 amino acids
- Molecular mass:
- 31499 Da
- Quaternary structure:
-
- Interacts with CRACR2A/EFCAB4B.
Post-translational modifications for ORAI3 Gene
Other Protein References for ORAI3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences ORAI3 Antibody (LS-B2385) and ORAI3 Antibody (LS-B2718)
- HUABIO Orai3 Antibody (ER1803-12)
-
Custom Antibody ServicesOriGene Antibodies for ORAI3
- Novus Biologicals Antibodies for ORAI3
-
Abcam antibodies for ORAI3
- Invitrogen Antibodies for ORAI3 (AFLGC-ORAI3)
-
Biorbyt antibodies for ORAI3
- Sino Biological Antibodies for ORAI3
Protein Products
-
OriGene Purified Proteins for ORAI3
- Search Origene for MassSpec and Protein Over-expression Lysates for ORAI3
- Origene Custom Protein Services for ORAI3
-
Signalway Proteins for ORAI3
No data available for DME Specific Peptides for ORAI3 Gene
Domains & Families for ORAI3 Gene
Gene Families for ORAI3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
- Transporters
Protein Domains for ORAI3 Gene
- InterPro:
- Blocks:
-
- Protein of unknown function DUF1650
- ProtoNet:
Suggested Antigen Peptide Sequences for ORAI3 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ60134, highly similar to Protein orai-3 (B4DPC5_HUMAN)
- Transmembrane protein 142C (ORAI3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9BRQ5- Family:
-
- Belongs to the Orai family.
Function for ORAI3 Gene
Molecular function for ORAI3 Gene
- UniProtKB/Swiss-Prot Function:
- Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
Phenotypes From GWAS Catalog for ORAI3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 19887627 |
| GO:0015279 | store-operated calcium channel activity | IBA | 21873635 |
Phenotypes for ORAI3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ORAI3 - Select products 50% OFF >
- * ORAI3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ORAI3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ORAI3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ORAI3
miRNA for ORAI3 Gene
- miRTarBase miRNAs that target ORAI3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ORAI3
- Browse OriGene Inhibitory RNA Products For ORAI3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ORAI3
Clone Products
- Applied Biological Materials (abm): Clones for ORAI3 - Select products 50% OFF >
- * ORAI3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ORAI3
- Addgene plasmids for ORAI3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ORAI3
Cell Line Products
-
Horizon Cell Lines for ORAI3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ORAI3 Gene
Localization for ORAI3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ORAI3 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 3 |
| cytosol | 3 |
| extracellular | 2 |
| peroxisome | 2 |
| endoplasmic reticulum | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0016020 | membrane | IEA,IBA | 21873635 |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for ORAI3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Calcium signaling pathway | ||
| 2 | B Cell Receptor Signaling Pathway (sino) | ||
Pathways by source for ORAI3 Gene
1 Sino Biological pathway for ORAI3 Gene
1 KEGG pathway for ORAI3 Gene
Interacting Proteins for ORAI3 Gene
Selected Interacting proteins:
Q9BRQ5-ORAI3_HUMAN
ENSP00000322249
for ORAI3 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for ORAI3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002115 | store-operated calcium entry | IBA | 21873635 |
| GO:0070588 | calcium ion transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for ORAI3 Gene
Drugs & Compounds for ORAI3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| 2-APB | Pharma | Channel blocker, Pore Blocker, Antagonist, Gating inhibitor, Activator, Agonist, Potentiation | IP3 receptor antagonist. Also TRP channel modulator | 0 | ||
| ML 9 hydrochloride | Pharma | Myosin light chain kinase inhibitor | 0 | |||
| SKF 96365 hydrochloride | Pharma | SOCE inhibitor, TRPC channel blocker; also inhibits store-operated Ca2+ entry | 0 | |||
| YM 58483 | Pharma | Inhibitor of SOCE in non-excitable cells | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 5J 4 |
|
827001-82-1 |
|
|
(5) Tocris Compounds for ORAI3 Gene
| Compound | Action | Cas Number |
|---|---|---|
| 2-APB | IP3 receptor antagonist. Also TRP channel modulator | 524-95-8 |
| 5J 4 | CRAC channel blocker; anti-inflammatory | 827001-82-1 |
| ML 9 hydrochloride | Myosin light chain kinase inhibitor | 105637-50-1 |
| SKF 96365 hydrochloride | TRPC channel blocker; also inhibits store-operated Ca2+ entry | 130495-35-1 |
| YM 58483 | Inhibitor of SOCE in non-excitable cells | 223499-30-7 |
Transcripts for ORAI3 Gene
mRNA/cDNA for ORAI3 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000318663 2204 nts (view in UCSC)
- ENST00000562699 628 nts (view in UCSC)
- ENST00000563161 976 nts (view in UCSC)
- ENST00000566237 1393 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for ORAI3 - Select products 50% OFF >
- * ORAI3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for ORAI3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ORAI3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ORAI3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ORAI3
- Browse OriGene Inhibitory RNA Products For ORAI3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ORAI3
Clone Products
- Applied Biological Materials (abm): Clones for ORAI3 - Select products 50% OFF >
- * ORAI3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for ORAI3
- Addgene plasmids for ORAI3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ORAI3
Relevant External Links for ORAI3 Gene
- GeneLoc Exon Structure for
- ORAI3
Expression for ORAI3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for ORAI3
SOURCE GeneReport for Unigene cluster for ORAI3 Gene:
Hs.745104mRNA Expression by UniProt/SwissProt for ORAI3 Gene:
Q9BRQ5-ORAI3_HUMAN
Tissue specificity:
Expressed in both naive and effector T helper cells with higher levels in effector cells.
Evidence on tissue expression from TISSUES for ORAI3 Gene
- Lung(4.4)
- Blood(2.5)
- Muscle(2.4)
- Kidney(2.4)
- Nervous system(2.3)
- Heart(2.2)
Primer Products
-
OriGene qPCR primer pairs for ORAI3
-
OriGene qPCR primer pairs and template standards for ORAI3
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for ORAI3 Gene
Orthologs for ORAI3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | ORAI3 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | ORAI3 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | ORAI3 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Orai3 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Orai3 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | ORAI3 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | ORAI3 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | ORAI3 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | orai1b 31 |
|
ManyToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005071 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | olf186-F 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | orai-1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8521 31 |
|
OneToMany | |
| Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.15111 30 |
|
- Species where no ortholog for ORAI3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
Evolution for ORAI3 Gene
- ENSEMBL:
- Gene Tree for ORAI3 (if available)
- TreeFam:
- Gene Tree for ORAI3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for ORAI3: view image
Paralogs for ORAI3 Gene
Variants for ORAI3 Gene
Residual Variation Intolerance Score:
21.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.98;
20.25% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for ORAI3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ORAI3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for ORAI3 Gene
Disorders for ORAI3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| estrogen-receptor negative breast cancer |
|
|
| myopathy, tubular aggregate, 1 |
|
|
| stormorken syndrome |
|
|
| combined t cell and b cell immunodeficiency |
|
|
Search ORAI3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for ORAI3
No data available for UniProtKB/Swiss-Prot and Genatlas for ORAI3 Gene
Publications for ORAI3 Gene
- A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. (PMID: 16582901) Feske S … Rao A (Nature 2006) 2 3 4
- A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels. (PMID: 26956485) Saul S … Bogeski I (Science signaling 2016) 2 3
- Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle. (PMID: 26718630) Spinelli AM … Trebak M (American journal of physiology. Cell physiology 2016) 2 3
- The neglected CRAC proteins: Orai2, Orai3, and STIM2. (PMID: 23890118) Hoth M … Niemeyer BA (Current topics in membranes 2013) 2 3
- A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. (PMID: 20418871) Srikanth S … Gwack Y (Nature cell biology 2010) 3 4
ExternalLinks
Products for ORAI3 Gene
- Custom Antibody ServicesOriGene Antibodies for ORAI3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ORAI3
- Search Origene for MassSpec and Protein Over-expression Lysates for ORAI3
- Origene Custom Protein Services for ORAI3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ORAI3
- Browse OriGene Inhibitory RNA Products For ORAI3
- OriGene qPCR primer pairs for ORAI3
- OriGene qPCR primer pairs and template standards for ORAI3
- OriGene CRISPR knockouts for ORAI3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ORAI3
- Sino Biological Human cDNA Clone for ORAI3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for ORAI3
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for ORAI3
- Novus Biologicals proteins and lysates for ORAI3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for ORAI3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for ORAI3 (AFLGC-ORAI3)
- VectorBuilder Custom and pre-made DNA vectors for ORAI3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for ORAI3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for ORAI3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for ORAI3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for ORAI3
- Addgene plasmids for ORAI3
- antibodies-online: Show 17 available ORAI3 Antibodies ranked by validation data
- Compare Top ORAI3 Antibodies
- antibodies-online: Search results for available ORAI3 related products ranked by validation data
- antibodies-online: Search results for available ORAI3 related products ranked by validation data
- Custom Antibody ServicesProSci Antibodies for ORAI3
- Search for ORAI3 Proteins at ProSci
- Horizon Cell Lines for ORAI3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for ORAI3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for ORAI3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for ORAI3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for ORAI3
- Biorbyt antibodies for ORAI3
- Signalway Proteins for ORAI3
Sources for ORAI3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB