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Aliases for OR9G4 Gene

Aliases for OR9G4 Gene

  • Olfactory Receptor Family 9 Subfamily G Member 4 2 3 5
  • Olfactory Receptor OR11-216 3 4
  • Olfactory Receptor, Family 9, Subfamily G, Member 4 2
  • Olfactory Receptor 9G4 3
  • OR11-216 3

External Ids for OR9G4 Gene

Previous GeneCards Identifiers for OR9G4 Gene

  • GC11U990392
  • GC11M056286
  • GC11M056266
  • GC11M056510

Summaries for OR9G4 Gene

Entrez Gene Summary for OR9G4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9G4 Gene

OR9G4 (Olfactory Receptor Family 9 Subfamily G Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR9G1.

UniProtKB/Swiss-Prot for OR9G4 Gene

  • Odorant receptor.

Gene Wiki entry for OR9G4 Gene

Additional gene information for OR9G4 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9G4 Gene

Genomics for OR9G4 Gene

GeneHancer (GH) Regulatory Elements for OR9G4 Gene

Top Transcription factor binding sites by QIAGEN in the OR9G4 gene promoter:
  • Pbx1a
  • COMP1
  • AML1a
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • HOXA3

Genomic Locations for OR9G4 Gene

Genomic Locations for OR9G4 Gene
7,475 bases
Minus strand
985 bases
Minus strand

Genomic View for OR9G4 Gene

Genes around OR9G4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR9G4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR9G4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9G4 Gene

Proteins for OR9G4 Gene

  • Protein details for OR9G4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 9G4
    Protein Accession:
    Secondary Accessions:
    • Q6IF62
    • Q96RA9

    Protein attributes for OR9G4 Gene

    327 amino acids
    Molecular mass:
    36344 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05959.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR9G4 Gene

Post-translational modifications for OR9G4 Gene

Other Protein References for OR9G4 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9G4 Gene

Domains & Families for OR9G4 Gene

Gene Families for OR9G4 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR9G4 Gene

Suggested Antigen Peptide Sequences for OR9G4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9G4: view

Function for OR9G4 Gene

Molecular function for OR9G4 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR9G4 Gene

Gene Ontology (GO) - Molecular Function for OR9G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9G4: view
genes like me logo Genes that share phenotypes with OR9G4: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR9G4 Gene

Localization for OR9G4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9G4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR9G4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR9G4: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR9G4 Gene

Pathways & Interactions for OR9G4 Gene

genes like me logo Genes that share pathways with OR9G4: view

Pathways by source for OR9G4 Gene

Interacting Proteins for OR9G4 Gene

Gene Ontology (GO) - Biological Process for OR9G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA,IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9G4: view

No data available for SIGNOR curated interactions for OR9G4 Gene

Drugs & Compounds for OR9G4 Gene

No Compound Related Data Available

Transcripts for OR9G4 Gene

mRNA/cDNA for OR9G4 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR9G4 Gene

Olfactory receptor, family 9, subfamily G, member 4:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR9G4 Gene

No ASD Table

Relevant External Links for OR9G4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR9G4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR9G4 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR9G4 Gene:


SOURCE GeneReport for Unigene cluster for OR9G4 Gene:

genes like me logo Genes that share expression patterns with OR9G4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR9G4 Gene

Orthologs for OR9G4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR9G4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466578 33
  • 98.98 (n)
OR9G4 34
  • 98 (a)
(Canis familiaris)
Mammalia OR9G4 34 33
  • 88.21 (n)
(Mus musculus)
Mammalia Or9g4 51 Olfr1006 16 34 33
  • 84.94 (n)
Or9g21-ps 51 Olfr1004-ps1
  • chr2:85,656,239-85,656,835
Or9g4b 51 Olfr1015
  • chr2:85,785,513-85,786,448
(Bos Taurus)
Mammalia LOC506891 33
  • 84.57 (n)
-- 34
  • 84 (a)
-- 34
  • 81 (a)
(Rattus norvegicus)
Mammalia Olr450 33
  • 84.08 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 83 (a)
-- 34
  • 80 (a)
-- 34
  • 79 (a)
Species where no ortholog for OR9G4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9G4 Gene

Gene Tree for OR9G4 (if available)
Gene Tree for OR9G4 (if available)
Evolutionary constrained regions (ECRs) for OR9G4: view image

Paralogs for OR9G4 Gene

Paralogs for OR9G4 Gene

(439) SIMAP similar genes for OR9G4 Gene using alignment to 1 proteins:

  • OR9G4_HUMAN Pseudogenes for OR9G4 Gene

genes like me logo Genes that share paralogs with OR9G4: view

Variants for OR9G4 Gene

Sequence variations from dbSNP and Humsavar for OR9G4 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000720385 -- 56,744,814(-) T/C upstream_transcript_variant
rs1004703385 -- 56,745,644(-) C/T upstream_transcript_variant
rs1005287420 -- 56,743,952(-) G/A upstream_transcript_variant
rs1005697477 -- 56,744,133(-) T/C upstream_transcript_variant
rs1006289786 -- 56,742,742(-) A/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR9G4 Gene

Variant ID Type Subtype PubMed ID
nsv468577 CNV gain 19166990
nsv555101 CNV gain 21841781

Variation tolerance for OR9G4 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.42; 85.63% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR9G4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9G4 Gene

Disorders for OR9G4 Gene

Additional Disease Information for OR9G4

No disorders were found for OR9G4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR9G4 Gene

Publications for OR9G4 Gene

  1. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q … O'Donnell CJ (BMC medical genetics 2007) 3 44 58
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 58
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4 58
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR9G4 Gene

Sources for OR9G4 Gene

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