Aliases for OR8G2P Gene
Aliases for OR8G2P Gene
- Olfactory Receptor Family 8 Subfamily G Member 2 Pseudogene 2 3 5
- Olfactory Receptor, Family 8, Subfamily G, Member 2 2 3
- Olfactory Receptor OR11-292 3 4
- Olfactory Receptor TPCR120 3 4
- Olfactory Receptor 8G4 3 4
- OR8G2 3 4
- OR8G4 3 4
- Olfactory Receptor, Family 8, Subfamily G, Member 2 Pseudogene 2
- Olfactory Receptor, Family 8, Subfamily G, Member 4 3
External Ids for OR8G2P Gene
- HGNC: 8485
- Entrez Gene: 26492
- Ensembl: ENSG00000181214
- UniProtKB: Q6IF36
- HORDE: OR8G2P
Previous HGNC Symbols for OR8G2P Gene
- OR8G4
- OR8G2
Summaries for OR8G2P Gene
-
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
GeneCards Summary for OR8G2P Gene
OR8G2P (Olfactory Receptor Family 8 Subfamily G Member 2 Pseudogene) is a Pseudogene. Among its related pathways are GPCRs, Other and Signaling by GPCR.
UniProtKB/Swiss-Prot for OR8G2P Gene
-
Odorant receptor.
Additional gene information for OR8G2P Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8G2P Gene
Genomics for OR8G2P Gene
GeneHancer (GH) Regulatory Elements for OR8G2P Gene
Promoters and enhancers for OR8G2P Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around OR8G2P on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for OR8G2P Gene
Genomic Locations for OR8G2P Gene
- chr11:124,224,639-124,225,678
- (GRCh38/hg38)
- Size:
- 1,040 bases
- Orientation:
- Plus strand
- chr11:124,095,398-124,096,365
- (GRCh37/hg19)
- Size:
- 968 bases
- Orientation:
- Plus strand
Genomic View for OR8G2P Gene
Genes around OR8G2P on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q24.2 by Entrez Gene
- 11q24.2 by HGNC
- 11q24.2 by Ensembl
OR8G2P Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR8G2P Gene
Proteins for OR8G2P Gene
-
Protein details for OR8G2P Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6IF36-O8G2P_HUMAN
- Recommended name:
- Putative olfactory receptor 8G2
- Protein Accession:
- Q6IF36
- Q15614
- Q6IF38
Protein attributes for OR8G2P Gene
- Size:
- 304 amino acids
- Molecular mass:
- 33950 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for OR8G2P Gene
No Post-translational modifications
Other Protein References for OR8G2P Gene
- REFSEQ proteins:
- HORDE protein sequence:
Antibody Products
- Novus Biologicals Antibodies for OR8G2P
- Invitrogen Antibodies for OR8G2P
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Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR8G2P
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Assay Products
No data available for DME Specific Peptides for OR8G2P Gene
Domains & Families for OR8G2P Gene
Gene Families for OR8G2P Gene
Protein Domains for OR8G2P Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for OR8G2P Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6IF36- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR8G2P Gene
Molecular function for OR8G2P Gene
- UniProtKB/Swiss-Prot Function:
- Odorant receptor.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | IBA | -- |
| GO:0005549 | odorant binding | IBA | -- |
Phenotypes for OR8G2P Gene
- GenomeRNAi human phenotypes for OR8G2P:
Animal Model Products
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-
CRISPR Products
-
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miRNA Products
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Clone Products
- Sino Biological Human cDNA Clone for OR8G2P
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for OR8G2P
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR8G2P
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-
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Cell Line Products
-
Horizon Cell Lines for OR8G2P
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR8G2P Gene
Localization for OR8G2P Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR8G2P Gene
- Cell membrane; Multi-pass membrane protein.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR8G2P Gene
Pathways & Interactions for OR8G2P Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory Signaling Pathway | ||
| 3 | GPCRs, Other | ||
Pathways by source for OR8G2P Gene
1 BioSystems pathway for OR8G2P Gene
4 Reactome pathways for OR8G2P Gene
1 KEGG pathway for OR8G2P Gene
Interacting Proteins for OR8G2P Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007186 | G-protein coupled receptor signaling pathway | IBA | -- |
| GO:0007608 | sensory perception of smell | IBA | -- |
| GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
No data available for SIGNOR curated interactions for OR8G2P Gene
Transcripts for OR8G2P Gene
mRNA/cDNA for OR8G2P Gene
- (1) REFSEQ mRNAs :
- (1) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000412796 908 bps
CRISPR Products
-
OriGene CRISPR knockouts for OR8G2P
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-
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miRNA Products
Inhibitory RNA Products
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Clone Products
- Sino Biological Human cDNA Clone for OR8G2P
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for OR8G2P
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR8G2P
- genomics-online: cdna clones - Search results for available OR8G2 gene related products
- orf clones - Search results for available OR8G2 gene related products
- Applied Biological Materials Clones for OR8G2P
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for OR8G2P Gene
NURSA nuclear receptor signaling pathways regulating expression of OR8G2P Gene:
OR8G2P
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for OR8G2P
- genomics-online: primer clones - Search results for available OR8G2 gene related products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR8G2P Gene
Orthologs for OR8G2P Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| dog (Canis familiaris) |
Mammalia | LOC100687661 33 |
|
||
| cow (Bos Taurus) |
Mammalia | LOC513062 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Or8g2 51 Olfr229 16 33 |
|
|
|
| Or8g20 51 Olfr44 |
|
|
|||
| Or8g23 51 Olfr937 |
|
|
|||
| Or8g24 51 Olfr938 |
|
|
|||
| Or8g2b 51 Olfr971 |
|
|
|||
| Or8g30 51 Olfr948 |
|
|
|||
| Or8g33 51 Olfr952 |
|
|
|||
| Or8g35 51 Olfr955 |
|
|
|||
| Or8g36 51 Olfr957 |
|
|
|||
| Or8g37 51 Olfr970 |
|
|
- Species where no ortholog for OR8G2P was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for OR8G2P Gene
No data available for Paralogs for OR8G2P Gene
Variants for OR8G2P Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1004772876 | -- | 124,224,588(+) | A/G | upstream_transcript_variant | |
| rs1004840429 | -- | 124,225,933(+) | C/T | downstream_transcript_variant | |
| rs1004957791 | -- | 124,224,315(+) | T/A | upstream_transcript_variant | |
| rs1005285322 | -- | 124,224,235(+) | C/A | upstream_transcript_variant | |
| rs1006218029 | -- | 124,222,864(+) | A/G | upstream_transcript_variant |
Additional Variant Information for OR8G2P Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- OR8G2P
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OR8G2P Gene
Disorders for OR8G2P Gene
Additional Disease Information for OR8G2P
No disorders were found for OR8G2P Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR8G2P Gene
Publications for OR8G2P Gene
- Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P … Parmentier M (Genomics 1997) 2 3 4 58
- The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
Products for OR8G2P Gene
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Sources for OR8G2P Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
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- (133) ENCODE
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- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt