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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
OR8G2P (Olfactory Receptor Family 8 Subfamily G Member 2 Pseudogene) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and GPCRs, Other.
GO ID | Qualified GO term | Evidence | PubMed IDs |
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GO:0004930 | G protein-coupled receptor activity | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
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GO:0005886 | plasma membrane | TAS | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
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1 | Signaling by GPCR | ||
2 | Olfactory transduction | ||
3 | GPCRs, Other |
GO ID | Qualified GO term | Evidence | PubMed IDs |
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GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
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Dog (Canis familiaris) |
Mammalia | LOC100687661 30 |
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Cow (Bos Taurus) |
Mammalia | LOC513062 30 |
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Mouse (Mus musculus) |
Mammalia | Or8g2 46 Olfr229 30 17 |
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Or8g20 46 Olfr44 |
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Or8g23 46 Olfr937 |
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Or8g24 46 Olfr938 |
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Or8g2b 46 Olfr971 |
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Or8g30 46 Olfr948 |
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Or8g33 46 Olfr952 |
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Or8g35 46 Olfr955 |
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Or8g36 46 Olfr957 |
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Or8g37 46 Olfr970 |
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No disorders were found for OR8G2P Gene.