Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR8G2P Gene

Aliases for OR8G2P Gene

  • Olfactory Receptor Family 8 Subfamily G Member 2 Pseudogene 2 3 5
  • Olfactory Receptor, Family 8, Subfamily G, Member 2 2 3
  • Putative Olfactory Receptor 8G2 3 4
  • Olfactory Receptor OR11-292 3 4
  • Olfactory Receptor TPCR120 3 4
  • Olfactory Receptor 8G4 3 4
  • HSTPCR120 2 3
  • TPCR120 2 3
  • ORL206 2 3
  • ORL486 2 3
  • OR8G2 3 4
  • OR8G4 3 4
  • Olfactory Receptor, Family 8, Subfamily G, Member 2 Pseudogene 2
  • Olfactory Receptor, Family 8, Subfamily G, Member 4 3
  • Olfactory Receptor Family 8 Subfamily G Member 2 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor OR11-297 3
  • OR8G2P 5

External Ids for OR8G2P Gene

Previous HGNC Symbols for OR8G2P Gene

  • OR8G4
  • OR8G2

Summaries for OR8G2P Gene

Entrez Gene Summary for OR8G2P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8G2P Gene

OR8G2P (Olfactory Receptor Family 8 Subfamily G Member 2 Pseudogene) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and GPCRs, Other.

UniProtKB/Swiss-Prot Summary for OR8G2P Gene

Gene Wiki entry for OR8G2P Gene

Additional gene information for OR8G2P Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR8G2P Gene

Genomics for OR8G2P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR8G2P Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR8G2P on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OR8G2P

Genomic Locations for OR8G2P Gene

Genomic Locations for OR8G2P Gene
chr11:124,224,639-124,225,678
(GRCh38/hg38)
Size:
1,040 bases
Orientation:
Plus strand
chr11:124,095,398-124,096,365
(GRCh37/hg19)
Size:
968 bases
Orientation:
Plus strand

Genomic View for OR8G2P Gene

Genes around OR8G2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR8G2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR8G2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8G2P Gene

Proteins for OR8G2P Gene

  • Protein details for OR8G2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IF36-O8G2P_HUMAN
    Recommended name:
    Putative olfactory receptor 8G2
    Protein Accession:
    Q6IF36
    Secondary Accessions:
    • Q15614
    • Q6IF38

    Protein attributes for OR8G2P Gene

    Size:
    304 amino acids
    Molecular mass:
    33950 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8G2P Gene

Post-translational modifications for OR8G2P Gene

  • Glycosylation at Asn18

Other Protein References for OR8G2P Gene

REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR8G2P Gene

Domains & Families for OR8G2P Gene

Gene Families for OR8G2P Gene

Protein Domains for OR8G2P Gene

Suggested Antigen Peptide Sequences for OR8G2P Gene

GenScript: Design optimal peptide antigens:
  • Olfactory receptor TPCR120 (OR8G2_HUMAN)
  • Olfactory receptor, family 8, subfamily G, member 2 (Q6IF36_HUMAN)
  • Seven transmembrane helix receptor (Q8N0Y1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6IF36

UniProtKB/Swiss-Prot:

O8G2P_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR8G2P: view

Function for OR8G2P Gene

Molecular function for OR8G2P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR8G2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
genes like me logo Genes that share ontologies with OR8G2P: view
genes like me logo Genes that share phenotypes with OR8G2P: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR8G2P

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR8G2P Gene

Localization for OR8G2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8G2P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR8G2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR8G2P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR8G2P Gene

Pathways & Interactions for OR8G2P Gene

genes like me logo Genes that share pathways with OR8G2P: view

Pathways by source for OR8G2P Gene

1 BioSystems pathway for OR8G2P Gene
1 KEGG pathway for OR8G2P Gene

Interacting Proteins for OR8G2P Gene

Gene Ontology (GO) - Biological Process for OR8G2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR8G2P: view

No data available for SIGNOR curated interactions for OR8G2P Gene

Drugs & Compounds for OR8G2P Gene

No Compound Related Data Available

Transcripts for OR8G2P Gene

mRNA/cDNA for OR8G2P Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR8G2P

Alternative Splicing Database (ASD) splice patterns (SP) for OR8G2P Gene

No ASD Table

Relevant External Links for OR8G2P Gene

GeneLoc Exon Structure for
OR8G2P

Expression for OR8G2P Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR8G2P

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR8G2P Gene

Orthologs for OR8G2P Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8G2P Gene

Organism Taxonomy Gene Similarity Type Details
Dog
(Canis familiaris)
Mammalia LOC100687661 30
  • 86.64 (n)
Cow
(Bos Taurus)
Mammalia LOC513062 30
  • 85.48 (n)
Mouse
(Mus musculus)
Mammalia Or8g2 46 Olfr229 30 17
  • 83.51 (n)
Or8g20 46 Olfr44
  • chr9:39,484,310-39,485,251
Or8g23 46 Olfr937
  • chr9:39,059,732-39,060,664
Or8g24 46 Olfr938
  • chr9:39,077,799-39,078,743
Or8g2b 46 Olfr971
  • chr9:39,839,436-39,840,356
Or8g30 46 Olfr948
  • chr9:39,318,650-39,319,612
Or8g33 46 Olfr952
  • chr9:39,426,128-39,427,069
Or8g35 46 Olfr955
  • chr9:39,469,783-39,470,724
Or8g36 46 Olfr957
  • chr9:39,510,786-39,511,718
Or8g37 46 Olfr970
  • chr9:39,819,641-39,820,573
Species where no ortholog for OR8G2P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR8G2P Gene

ENSEMBL:
Gene Tree for OR8G2P (if available)
TreeFam:
Gene Tree for OR8G2P (if available)

Paralogs for OR8G2P Gene

No data available for Paralogs for OR8G2P Gene

Variants for OR8G2P Gene

Additional dbSNP identifiers (rs#s) for OR8G2P Gene

Structural Variations from Database of Genomic Variants (DGV) for OR8G2P Gene

Variant ID Type Subtype PubMed ID
dgv57n111 CNV duplication 26073780
dgv82n21 CNV gain 19592680
esv2745180 CNV deletion 23290073
esv2745181 CNV deletion 23290073
esv3627973 CNV gain 21293372
nsv442245 CNV gain 18776908
nsv826110 CNV gain 20364138
nsv975237 CNV duplication 23825009

Additional Variant Information for OR8G2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR8G2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for OR8G2P Gene

Disorders for OR8G2P Gene

Additional Disease Information for OR8G2P

No disorders were found for OR8G2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR8G2P Gene

Publications for OR8G2P Gene

  1. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P … Parmentier M (Genomics 1997) 2 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for OR8G2P Gene

Sources for OR8G2P Gene