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Aliases for OR7G2 Gene

Aliases for OR7G2 Gene

  • Olfactory Receptor Family 7 Subfamily G Member 2 2 3 5
  • Olfactory Receptor OR19-6 3 4
  • Olfactory Receptor 19-13 3 4
  • OR19-13 3 4
  • OST260 3 4
  • Olfactory Receptor, Family 7, Subfamily G, Member 2 2
  • Olfactory Receptor 7G2 3
  • OR19-6 3

External Ids for OR7G2 Gene

Previous GeneCards Identifiers for OR7G2 Gene

  • GC19U990181
  • GC19M009074
  • GC19M009212

Summaries for OR7G2 Gene

Entrez Gene Summary for OR7G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7G2 Gene

OR7G2 (Olfactory Receptor Family 7 Subfamily G Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G1.

UniProtKB/Swiss-Prot for OR7G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR7G2 Gene

Additional gene information for OR7G2 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7G2 Gene

Genomics for OR7G2 Gene

GeneHancer (GH) Regulatory Elements for OR7G2 Gene

Top Transcription factor binding sites by QIAGEN in the OR7G2 gene promoter:
  • Meis-1
  • HOXA9B
  • HOXA9
  • CREB
  • Meis-1b
  • Nkx3-1 v1
  • Nkx3-1
  • Nkx3-1 v2
  • Nkx3-1 v3
  • Nkx3-1 v4

Genomic Locations for OR7G2 Gene

Genomic Locations for OR7G2 Gene
7,069 bases
Minus strand
1,038 bases
Minus strand

Genomic View for OR7G2 Gene

Genes around OR7G2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR7G2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR7G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7G2 Gene

Proteins for OR7G2 Gene

  • Protein details for OR7G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 7G2
    Protein Accession:
    Secondary Accessions:
    • Q6IFJ4
    • Q96RA0

    Protein attributes for OR7G2 Gene

    324 amino acids
    Molecular mass:
    35931 Da
    Quaternary structure:
    No Data Available
    • Sequence=DAA04666.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR7G2 Gene

Post-translational modifications for OR7G2 Gene

Other Protein References for OR7G2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7G2 Gene

Domains & Families for OR7G2 Gene

Gene Families for OR7G2 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR7G2 Gene

Suggested Antigen Peptide Sequences for OR7G2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7G2: view

Function for OR7G2 Gene

Molecular function for OR7G2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA,IBA --
genes like me logo Genes that share ontologies with OR7G2: view
genes like me logo Genes that share phenotypes with OR7G2: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR7G2 Gene

Localization for OR7G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7G2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR7G2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS,IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA,IEA --
genes like me logo Genes that share ontologies with OR7G2: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR7G2 Gene

Pathways & Interactions for OR7G2 Gene

genes like me logo Genes that share pathways with OR7G2: view

Pathways by source for OR7G2 Gene

Interacting Proteins for OR7G2 Gene

Gene Ontology (GO) - Biological Process for OR7G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA,IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA,IBA --
genes like me logo Genes that share ontologies with OR7G2: view

No data available for SIGNOR curated interactions for OR7G2 Gene

Drugs & Compounds for OR7G2 Gene

No Compound Related Data Available

Transcripts for OR7G2 Gene

mRNA/cDNA for OR7G2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7G2 Gene

Olfactory receptor, family 7, subfamily G, member 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR7G2 Gene

No ASD Table

Relevant External Links for OR7G2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR7G2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR7G2 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR7G2 Gene:


SOURCE GeneReport for Unigene cluster for OR7G2 Gene:

genes like me logo Genes that share expression patterns with OR7G2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR7G2 Gene

Orthologs for OR7G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7G2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR7G1 33
  • 82.25 (n)
OR7G2 34
  • 74 (a)
(Canis familiaris)
Mammalia OR7G2 33
  • 81.16 (n)
OR28G07 34
  • 76 (a)
(Mus musculus)
Mammalia Or7g33 51 Olfr853 16 33
  • 72.35 (n)
Or7g34 51 Olfr854 34
  • 72 (a)
Or7g27 51 Olfr845 34
  • 72 (a)
Or7g31 51 Olfr850 34
  • 70 (a)
Or7g16 51 Olfr828 34
  • 70 (a)
Or7g20 51 Olfr835 34
  • 68 (a)
Or7g17 51 Olfr829 34
  • 68 (a)
Olfr844 34
  • 68 (a)
Or7g28 51 Olfr846 34
  • 67 (a)
Or7g30 51 Olfr849 34
  • 66 (a)
Or7g35 51 Olfr855 34
  • 66 (a)
Or7g29 51 Olfr847 34
  • 65 (a)
Or7g32 51 Olfr851 34
  • 64 (a)
Or7g18 51 Olfr830 34
  • 62 (a)
Olfr843 34
  • 62 (a)
Or7g21 51 Olfr836 34
  • 62 (a)
Or7g22 51 Olfr837
  • chr9:19,136,995-19,137,930
Or7g23 51 Olfr839
  • chr9:19,174,739-19,175,674
Or7g24-ps 51 Olfr840-ps1
  • chr9:19,204,868-19,205,669
Or7g26-ps 51 Olfr844-ps1
  • chr9:19,318,530-19,319,462
Or7n1-ps 51 Olfr848-ps1
  • chr9:19,403,642-19,404,529
Or7s1-ps 51 Olfr831-ps1
  • chr9:18,931,931-18,932,951
Or7s1-ps 51 Olfr833-ps1
  • chr9:18,970,010-18,970,873
(Rattus norvegicus)
Mammalia Olr1145 33
  • 72.02 (n)
Species where no ortholog for OR7G2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7G2 Gene

Gene Tree for OR7G2 (if available)
Gene Tree for OR7G2 (if available)
Evolutionary constrained regions (ECRs) for OR7G2: view image

Paralogs for OR7G2 Gene

Paralogs for OR7G2 Gene

(455) SIMAP similar genes for OR7G2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR7G2: view

Variants for OR7G2 Gene

Sequence variations from dbSNP and Humsavar for OR7G2 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000041975 -- 9,104,658(-) T/C upstream_transcript_variant
rs1000093746 -- 9,104,881(-) G/A upstream_transcript_variant
rs1001528959 -- 9,101,787(-) A/G downstream_transcript_variant
rs1006219253 -- 9,104,564(-) A/G upstream_transcript_variant
rs1006675405 -- 9,102,151(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR7G2 Gene

Variant ID Type Subtype PubMed ID
esv2762024 CNV gain 21179565
nsv1056401 CNV gain 25217958
nsv509720 CNV insertion 20534489
nsv961171 CNV duplication 23825009

Variation tolerance for OR7G2 Gene

Residual Variation Intolerance Score: 63.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.33; 63.06% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR7G2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7G2 Gene

Disorders for OR7G2 Gene

Additional Disease Information for OR7G2

No disorders were found for OR7G2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR7G2 Gene

Publications for OR7G2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 58
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR7G2 Gene

Sources for OR7G2 Gene

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