Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR7A2P Gene

Aliases for OR7A2P Gene

  • Olfactory Receptor Family 7 Subfamily A Member 2 Pseudogene 2 3 5
  • OR19-18 2 3
  • Hg1003 2 3
  • OLF4p 2 3
  • OR7A2 3 4
  • OR7A7 3 4
  • Olfactory Receptor, Family 7, Subfamily A, Member 2 Pseudogene 2
  • Olfactory Receptor, Family 7, Subfamily A, Member 7 3
  • Seven Transmembrane Helix Receptor 3
  • Putative Olfactory Receptor 7A2 4
  • Putative Olfactory Receptor 7A7 4
  • Olfactory Receptor 7A2 3
  • OR7A2P 5

External Ids for OR7A2P Gene

Previous HGNC Symbols for OR7A2P Gene

  • OR7A7
  • OR7A2

Previous GeneCards Identifiers for OR7A2P Gene

  • GC19M014837
  • GC19M014838
  • GC19M014974

Summaries for OR7A2P Gene

Entrez Gene Summary for OR7A2P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7A2P Gene

OR7A2P (Olfactory Receptor Family 7 Subfamily A Member 2 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot Summary for OR7A2P Gene

Additional gene information for OR7A2P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR7A2P Gene

Genomics for OR7A2P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR7A2P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J014876 Enhancer 0.2 Ensembl 0.4 -9.3 -9343 0.2 OR7A5 lnc-OR7A10-2 OR7A17 OR7A2P OR7A10
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR7A2P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OR7A2P Gene

Latest Assembly
chr19:14,863,586-14,867,358
(GRCh38/hg38)
Size:
3,773 bases
Orientation:
Minus strand

Previous Assembly
chr19:14,974,398-14,976,074
(GRCh37/hg19 by Entrez Gene)
Size:
1,677 bases
Orientation:
Minus strand

chr19:14,974,598-14,975,527
(GRCh37/hg19 by Ensembl)
Size:
930 bases
Orientation:
Minus strand

Genomic View for OR7A2P Gene

Genes around OR7A2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR7A2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR7A2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7A2P Gene

Proteins for OR7A2P Gene

  • Protein details for OR7A2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGA2-OR7A2_HUMAN
    Recommended name:
    Putative olfactory receptor 7A2
    Protein Accession:
    Q8NGA2
    Secondary Accessions:
    • Q96R95

    Protein attributes for OR7A2P Gene

    Size:
    310 amino acids
    Molecular mass:
    34430 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7A2P Gene

Post-translational modifications for OR7A2P Gene

  • Glycosylation at Asn6

Other Protein References for OR7A2P Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR7A2P Gene

Domains & Families for OR7A2P Gene

Gene Families for OR7A2P Gene

Protein Domains for OR7A2P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR7A2P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 7A7 (OR7A2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGA2

UniProtKB/Swiss-Prot:

OR7A2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7A2P: view

Function for OR7A2P Gene

Molecular function for OR7A2P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
GENATLAS Biochemistry:
olfactory receptor,family 7,subfamily A,member 2,pseudogene,G protein coupled receptor superfamily

Gene Ontology (GO) - Molecular Function for OR7A2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA 21873635
genes like me logo Genes that share ontologies with OR7A2P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR7A2P Gene

Localization for OR7A2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7A2P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR7A2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR7A2P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR7A2P Gene

Pathways & Interactions for OR7A2P Gene

PathCards logo

SuperPathways for OR7A2P Gene

genes like me logo Genes that share pathways with OR7A2P: view

Pathways by source for OR7A2P Gene

Gene Ontology (GO) - Biological Process for OR7A2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR7A2P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR7A2P Gene

Drugs & Compounds for OR7A2P Gene

No Compound Related Data Available

Transcripts for OR7A2P Gene

mRNA/cDNA for OR7A2P Gene

2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR7A2P Gene

No ASD Table

Relevant External Links for OR7A2P Gene

GeneLoc Exon Structure for
OR7A2P

Expression for OR7A2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR7A2P Gene

mRNA expression in normal human tissues for OR7A2P Gene
genes like me logo Genes that share expression patterns with OR7A2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR7A2P Gene

Orthologs for OR7A2P Gene

Evolution for OR7A2P Gene

ENSEMBL:
Gene Tree for OR7A2P (if available)
TreeFam:
Gene Tree for OR7A2P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR7A2P

No data available for Orthologs for OR7A2P Gene

Paralogs for OR7A2P Gene

(457) SIMAP similar genes for OR7A2P Gene using alignment to 1 proteins:

  • OR7A2_HUMAN
genes like me logo Genes that share paralogs with OR7A2P: view

No data available for Paralogs for OR7A2P Gene

Variants for OR7A2P Gene

Additional Variant Information for OR7A2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR7A2P
Leiden Open Variation Database (LOVD)
OR7A2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR7A2P Gene

Disorders for OR7A2P Gene

No disorders were found for OR7A2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR7A2P Gene

Publications for OR7A2P Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR7A2P Gene

Sources for OR7A2P Gene