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Aliases for OR7A17 Gene

Aliases for OR7A17 Gene

  • Olfactory Receptor Family 7 Subfamily A Member 17 2 3 5
  • Olfactory Receptor, Family 7, Subfamily A, Member 17 2
  • Olfactory Receptor OR19-20 3
  • Olfactory Receptor 7A17 3
  • BC85395_4 3
  • HTPCRX19 3

External Ids for OR7A17 Gene

Previous GeneCards Identifiers for OR7A17 Gene

  • GC19M015360
  • GC19M015384
  • GC19M014836
  • GC19M014852
  • GC19M014991

Summaries for OR7A17 Gene

Entrez Gene Summary for OR7A17 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7A17 Gene

OR7A17 (Olfactory Receptor Family 7 Subfamily A Member 17) is a Protein Coding gene. Among its related pathways are GPCRs, Other and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7A10.

UniProtKB/Swiss-Prot for OR7A17 Gene

  • Odorant receptor.

Gene Wiki entry for OR7A17 Gene

Additional gene information for OR7A17 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7A17 Gene

Genomics for OR7A17 Gene

GeneHancer (GH) Regulatory Elements for OR7A17 Gene

Promoters and enhancers for OR7A17 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J014678 Enhancer 0.4 FANTOM5 21.4 +207.2 207190 0.3 STAT1 OR7A17 OR1I1 SLC1A6 ZNF333 ADGRE3 ENSG00000275432
GH19J014389 Enhancer 0.4 FANTOM5 dbSUPER 4.6 +496.9 496853 0.2 DDX39A OR7A17 ADGRE5 PKN1 RFX1 ZNF333 IL27RA DCAF15 ENSG00000267379
GH19J014597 Enhancer 0.4 FANTOM5 dbSUPER 3.8 +288.3 288333 0.3 ADGRE3 ADGRE5 NOTCH3 OR7A17 OR1I1 PRKACA PKN1 ZNF333 RN7SL842P CLEC17A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR7A17 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR7A17 gene promoter:
  • Nkx3-1 v4
  • Nkx3-1 v3
  • Nkx3-1 v2
  • Nkx3-1 v1
  • Nkx3-1
  • NF-kappaB
  • NF-kappaB1
  • NF-kappaB2
  • RP58
  • NF-AT4

Genomic Locations for OR7A17 Gene

Genomic Locations for OR7A17 Gene
7,930 bases
Minus strand
1,127 bases
Minus strand

Genomic View for OR7A17 Gene

Genes around OR7A17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR7A17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR7A17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7A17 Gene

Proteins for OR7A17 Gene

  • Protein details for OR7A17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 7A17
    Protein Accession:
    Secondary Accessions:
    • Q6IFQ6
    • Q96R98

    Protein attributes for OR7A17 Gene

    309 amino acids
    Molecular mass:
    34013 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7A17 Gene

Post-translational modifications for OR7A17 Gene

  • Glycosylation at isoforms=5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR7A17 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7A17 Gene

Domains & Families for OR7A17 Gene

Gene Families for OR7A17 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR7A17 Gene

Suggested Antigen Peptide Sequences for OR7A17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7A17: view

Function for OR7A17 Gene

Molecular function for OR7A17 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7A17: view
genes like me logo Genes that share phenotypes with OR7A17: view

Animal Model Products

miRNA for OR7A17 Gene

miRTarBase miRNAs that target OR7A17

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR7A17 Gene

Localization for OR7A17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7A17 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR7A17 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7A17: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR7A17 Gene

Pathways & Interactions for OR7A17 Gene

genes like me logo Genes that share pathways with OR7A17: view

Pathways by source for OR7A17 Gene

1 KEGG pathway for OR7A17 Gene

Interacting Proteins for OR7A17 Gene

Gene Ontology (GO) - Biological Process for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7A17: view

No data available for SIGNOR curated interactions for OR7A17 Gene

Drugs & Compounds for OR7A17 Gene

No Compound Related Data Available

Transcripts for OR7A17 Gene

mRNA/cDNA for OR7A17 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7A17 Gene

Olfactory receptor, family 7, subfamily A, member 17:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR7A17 Gene

No ASD Table

Relevant External Links for OR7A17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR7A17 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR7A17 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR7A17 Gene:


SOURCE GeneReport for Unigene cluster for OR7A17 Gene:

genes like me logo Genes that share expression patterns with OR7A17: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR7A17 Gene

Orthologs for OR7A17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7A17 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC747830 33
  • 86.99 (n)
-- 34
  • 81 (a)
(Bos Taurus)
Mammalia LOC782513 33
  • 81.79 (n)
(Mus musculus)
Mammalia Or7a40 51 Olfr19 16 34 33
  • 78.68 (n)
Olfr1352 34
  • 74 (a)
Olfr1353 34
  • 71 (a)
Or7a35 51 Olfr1351 34
  • 68 (a)
Olfr1354 34
  • 65 (a)
Olfr8 34
  • 63 (a)
Or7a41 51 Olfr57
  • chr10:79,034,798-79,035,754
Species where no ortholog for OR7A17 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7A17 Gene

Gene Tree for OR7A17 (if available)
Gene Tree for OR7A17 (if available)
Evolutionary constrained regions (ECRs) for OR7A17: view image

Paralogs for OR7A17 Gene

Paralogs for OR7A17 Gene

(453) SIMAP similar genes for OR7A17 Gene using alignment to 1 proteins:

  • OR7AH_HUMAN Pseudogenes for OR7A17 Gene

genes like me logo Genes that share paralogs with OR7A17: view

Variants for OR7A17 Gene

Sequence variations from dbSNP and Humsavar for OR7A17 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000035896 -- 14,882,288(-) G/T upstream_transcript_variant
rs1006415803 -- 14,882,177(-) A/G upstream_transcript_variant
rs1006900047 -- 14,881,936(-) C/T upstream_transcript_variant
rs1007278256 -- 14,881,352(-) C/A/T coding_sequence_variant, missense_variant, stop_gained
rs1008531035 -- 14,882,791(-) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR7A17 Gene

Variant ID Type Subtype PubMed ID
dgv1719n106 CNV deletion 24896259
esv2669817 CNV deletion 23128226
esv2718221 CNV deletion 23290073
esv2718222 CNV deletion 23290073
esv3583259 CNV loss 25503493
esv3583261 CNV loss 25503493
esv3643754 CNV loss 21293372
esv3893167 CNV gain 25118596
nsv1123224 CNV deletion 24896259
nsv1148645 CNV deletion 26484159
nsv961188 CNV duplication 23825009

Variation tolerance for OR7A17 Gene

Residual Variation Intolerance Score: 80.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.79; 96.68% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR7A17 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7A17 Gene

Disorders for OR7A17 Gene

Additional Disease Information for OR7A17

No disorders were found for OR7A17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR7A17 Gene

Publications for OR7A17 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 58
  5. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M … Perret J (Nature 1992) 2 3 58

Products for OR7A17 Gene

Sources for OR7A17 Gene

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