Free for academic non-profit institutions. Other users need a Commercial license
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...
Aliases for OR6B3 Gene
Aliases for OR6B3 Gene
External Ids for OR6B3 Gene
- HGNC: 15042
- NCBI Entrez Gene: 150681
- Ensembl: ENSG00000178586
- UniProtKB/Swiss-Prot: Q8NGW1
- HORDE: OR6B3
Previous HGNC Symbols for OR6B3 Gene
- OR6B3P
Previous GeneCards Identifiers for OR6B3 Gene
- GC02U900017
- GC02M241306
- GC02M240689
- GC02M240633
- GC02M240984
Summaries for OR6B3 Gene
-
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
GeneCards Summary for OR6B3 Gene
OR6B3 (Olfactory Receptor Family 6 Subfamily B Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and odorant binding. An important paralog of this gene is OR6B2.
UniProtKB/Swiss-Prot Summary for OR6B3 Gene
-
Odorant receptor.
Additional gene information for OR6B3 Gene
- HGNC (15042)
- NCBI Entrez Gene (150681)
- Ensembl (ENSG00000178586)
- UniProtKB/Swiss-Prot (Q8NGW1)
- Open Targets Platform(ENSG00000178586)
- Alliance of Genome Resources
- Search for OR6B3 at DataMed
- Search for OR6B3 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR6B3 Gene
Genomics for OR6B3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OR6B3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02J240051 | Enhancer | 0.5 | FANTOM5 Ensembl | 250.7 | +1.8 | 1796 | 0.6 | SOX5 SOX13 | OR6B3 HSALNG0023548 OR6B2 | |
| GH02J240134 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE CraniofacialAtlas | 11.2 | -82.3 | -82280 | 3.2 | EZH2 BCLAF1 ZNF207 MYC POLR2A ZIC2 SMAD5 TARDBP ELK1 ETS1 | COPS9 lnc-OTOS-2 ANKMY1 CAPN10 OR6B3 NDUFA10 OR5S1P | |
| GH02J239926 | Enhancer | 1.3 | FANTOM5 ENCODE dbSUPER | 9.6 | +125.9 | 125889 | 2 | NCOR1 ZNF600 ATF2 ZIC2 CEBPB BHLHE40 TBP MAX ZNF217 TAF9B | NDUFA10 OR6B3 HSALNG0023542 HSALNG0023541 LOC401040 | |
| GH02J240098 | Enhancer | 0.5 | Ensembl | 11.3 | -42.7 | -42702 | 0.4 | RFX1 EGR2 EZH2 TARDBP ZFHX2 | HSALNG0023551 OR6B3 piR-60794-010 COPS9 | |
| GH02J239111 | Enhancer | 0.9 | Ensembl ENCODE dbSUPER | 4.9 | +940.1 | 940092 | 3.1 | ZNF341 MAFF ZNF316 MAFK MAX FOXA1 MAFG GLIS1 ZFP69B HLF | ENSG00000286307 OR6B3 lnc-NDUFA10-8 TWIST2 HDAC4 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OR6B3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OR6B3
- Top Transcription factor binding sites by QIAGEN in the OR6B3 gene promoter:
-
- ATF6
- CREB
- GATA-2
- MZF-1
- Nkx2-5
- Roaz
- RORalpha2
- SEF-1 (1)
- USF-1
- USF1
Genomic Locations for OR6B3 Gene
Latest Assembly
- chr2:240,044,571-240,053,521
- (GRCh38/hg38)
- Size:
- 8,951 bases
- Orientation:
- Minus strand
Previous Assembly
- chr2:240,983,988-240,992,938
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 8,951 bases
- Orientation:
- Minus strand
Genomic View for OR6B3 Gene
Genes around OR6B3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q37.3 by HGNC
- 2q37.3 by Entrez Gene
- 2q37.3 by Ensembl
OR6B3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR6B3 Gene
Proteins for OR6B3 Gene
-
Protein details for OR6B3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NGW1-OR6B3_HUMAN
- Recommended name:
- Olfactory receptor 6B3
- Protein Accession:
- Q8NGW1
- Q6IFH3
Protein attributes for OR6B3 Gene
- Size:
- 331 amino acids
- Molecular mass:
- 37232 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=DAA04687.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Post-translational modifications for OR6B3 Gene
Other Protein References for OR6B3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
- HORDE protein sequence:
Antibodies for research
- G Biosciences Immunotag™ OR6B3 Polyclonal Antibody
-
Custom Antibody ServicesOriGene Antibodies for OR6B3
- Invitrogen Antibodies for OR6B3 (AFLGC-OR6B3)
- antibodies-online: Show 3 available OR6B3 Antibodies ranked by validation data
- Compare Top OR6B3 Antibodies
-
Quality Products:
-
Boster Bio Antibodies for OR6B3
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR6B3
- Origene Custom Protein Services for OR6B3
- Novus Biologicals proteins for OR6B3
- antibodies-online: Show 3 available OR6B3 Proteins ranked by validation data
- Compare Top OR6B3 Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for OR6B3 Gene
Domains & Families for OR6B3 Gene
Gene Families for OR6B3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for OR6B3 Gene
- InterPro:
- Blocks:
-
- Olfactory receptor signature
Suggested Antigen Peptide Sequences for OR6B3 Gene
- GenScript: Design optimal peptide antigens:
-
- Olfactory receptor OR2-2 (OR6B3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8NGW1- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR6B3 Gene
Molecular function for OR6B3 Gene
- UniProtKB/Swiss-Prot Function:
- Odorant receptor.
Phenotypes From GWAS Catalog for OR6B3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | IBA | 21873635 |
| GO:0005549 | odorant binding | IBA | 21873635 |
Phenotypes for OR6B3 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for OR6B3 - Starting at $85 >
- * OR6B3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for OR6B3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR6B3
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR6B3
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR6B3
- Browse OriGene Inhibitory RNA Products For OR6B3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR6B3
Clone products for research
- Applied Biological Materials (abm): Clones for OR6B3 - Starting at $45 >
- * OR6B3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for OR6B3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR6B3
Cell Lines for research
-
Horizon Cell Lines for OR6B3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR6B3 Gene
Localization for OR6B3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR6B3 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
- Plasma membrane (2)
- Cytosol (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | IDA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for OR6B3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory transduction | ||
Pathways by source for OR6B3 Gene
4 Reactome pathways for OR6B3 Gene
1 KEGG pathway for OR6B3 Gene
Interacting Proteins for OR6B3 Gene
GPS-Prot Interaction Network for OR6B3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | IEA | -- |
| GO:0007608 | sensory perception of smell | IEA | -- |
| GO:0050896 | response to stimulus | IEA | -- |
| GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
No data available for SIGNOR curated interactions for OR6B3 Gene
Transcripts for OR6B3 Gene
mRNA/cDNA for OR6B3 Gene
- 1 REFSEQ mRNAs :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000319423 996 nts (view in UCSC)
- ENST00000641019 1097 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for OR6B3 - Starting at $85 >
- * OR6B3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for OR6B3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR6B3
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR6B3
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR6B3
- Browse OriGene Inhibitory RNA Products For OR6B3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR6B3
Clone products for research
- Applied Biological Materials (abm): Clones for OR6B3 - Starting at $45 >
- * OR6B3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for OR6B3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR6B3
Relevant External Links for OR6B3 Gene
- GeneLoc Exon Structure for
- OR6B3
Expression for OR6B3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Mesenchymal Stem Cells Subcutaneous White Adipose
-
Mesenchymal Stem Cells
- Mesenchymal Stem Cells Subcutaneous White Adipose
mRNA differential expression in normal tissues according to GTEx for OR6B3 Gene
This gene is overexpressed in Nerve - Tibial (x40.7).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR6B3
SOURCE GeneReport for Unigene cluster for OR6B3 Gene:
Hs.626616Primer products for research
-
OriGene qPCR primer pairs for OR6B3
Gene Expression Assays for research
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR6B3 Gene
Orthologs for OR6B3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Rat (Rattus norvegicus) |
Mammalia | Olr1345 29 |
|
||
| Mouse (Mus musculus) |
Mammalia | Or6b3 45 Olfr1414 29 16 30 |
|
ManyToMany |
|
| Olfr1415 30 |
|
ManyToMany | |||
| Olfr1416 30 |
|
ManyToMany | |||
| Or6b9 45 Olfr6 |
|
|
|||
| Cow (Bos Taurus) |
Mammalia | -- 30 |
|
ManyToMany | |
| -- 30 |
|
ManyToMany | |||
| Dog (Canis familiaris) |
Mammalia | -- 30 |
|
ManyToMany | |
| -- 30 |
|
ManyToMany | |||
| -- 30 |
|
ManyToMany | |||
| -- 30 |
|
ManyToMany | |||
| OR12C12 30 |
|
ManyToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 30 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 30 |
|
OneToMany |
- Species where no ortholog for OR6B3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for OR6B3 Gene
- ENSEMBL:
- Gene Tree for OR6B3 (if available)
- TreeFam:
- Gene Tree for OR6B3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for OR6B3: view image
- Alliance of Genome Resources:
- Additional Orthologs for OR6B3
Paralogs for OR6B3 Gene
Paralogs for OR6B3 Gene
- OR6B2 5
- OR6P1 5
- OR8I2 5
- OR6Q1 5
- OR5A2 5
- OR8D4 5
- OR5AS1 5
- OR8U1 5
- OR5AP2 5
- OR5A1 5
- OR11L1 5
- OR5I1 5
- OR8J3 5
- OR8H1 5
- OR10Q1 5
- OR8D1 5
- OR8B4 5
- OR5AU1 5
- OR10H4 5
- OR5L1 5
- OR8H2 5
- OR8H3 5
- OR8J1 5
- OR5M10 5
- OR9G4 5
- OR5B21 5
- OR8B8 5
- OR5P3 5
- OR5D18 5
- OR5L2 5
- OR8J2 5
- OR8U3 5
- OR5M11 5
- OR5M1 5
- OR5AR1 5
- OR5AN1 5
- OR10V1 5
- OR8G3P 5
- OR8G5 5
- OR8A1 5
- OR9H1P 5
- OR5P2 5
- OR10H3 5
- OR5D14 5
- OR5D16 5
- OR5F1 5
- OR5J2 5
- OR8K3 5
- OR5M8 5
- OR5B12 5
- OR5H2 5
- OR5K3 5
- OR5K1 5
- OR9K2 5
- OR8G1 5
- OR8D2 5
- OR8B3 5
- OR8B12 5
- OR13A1 5
- OR5C1 5
- OR5D3P 5
- OR5W2 5
- OR8K5 5
- ENSG00000284732 5
- OR5M9 5
- OR5AK3P 5
- OR9I1 5
- OR9Q2 5
- OR10W1 5
- OR5B2 5
- OR5H6 5
- OR5K4 5
- OR8G2P 5
- OR8B2 5
- OR8K1 5
- OR5M3 5
- OR5B3 5
- OR5H1 5
- OR5H14 5
- OR5K2 5
- OR14J1 5
- OR5D13 5
- OR5AK2 5
- OR5B17 5
- OR5AC2 5
- OR5H15 5
- OR14I1 5
- OR9Q1 5
- OR14L1P 5
- OR14C36 5
- OR14A2 5
- OR14K1 5
- OR14A16 5
- OR5H8 5
- OR5AL1 5
- OR5G3 5
- OR5AC1 5
(455) SIMAP similar genes for OR6B3 Gene using alignment to 2 proteins:
- OR6B3_HUMAN
- I0EZ58_HUMAN
- OR6B2
- OR6A2
- OR6B1
- OR6P1
- OR11A1
- OR6Y1
- OR2G3
- OR1L4
- OR1L6
- OR10T2
- OR6Q1
- OR5A2
- OR2W1
- OR1J1
- OR5AU1
- OR2B8P
- HSA12
- OR2J1
- OR2G6
- OR2B11
- OR5F1
- OR5AS1
- OR5AN1
- OR2B2
- OR1J4
- OR10R3P
- OR10C1
- OR8U1
- OR6N1
- OR8U8
- OR6N2
- OR5K1
- OR1D2
- OR5B21
- OR5B2
- OR5A1
- OR1S1
- OR1J2
- OR1E1
- OR10A7
- HSA10
- OR8I2
- OR8U9
- OR5G3
- OR10J4
- OR5AK3P
- OR2J2
- OR2D2
- OR2B6
- OR2B3
- OR1M1
- OR1L8
- OR10K1
- OR9G4
- OR8J3
- OR8B8
- OR8B3
- OR6X1
- PJCG1
- OR9K2
- OR6F1
- OR6C4
- OR5K2
- OR5AC1
- OR2K2
- OR2A25
- OR5V1
- OR5I1
- OR5H2
- OR2J3
- OR1L3
- OR1G1
- OR13C9
- OR13C8
- OR6C74
- OR10Q1
- OR9Q1
- OR8B12
- OR6V1
- OR8J2
- OR8A1
- OR6C76
- OR5AP2
- OR2G2
- OR1L1
- OR5B3
- OR2M4
- OR2C3
- OR1S2
- OR1F1
- OR1E2
- OR13G1
- OR13F1
- OR11H6
- OR10A3
- OR8G1
- OR2A5
- OR5AR1
- OR8K5
- OR8H2
- OR8J1
- OR8B2
- OR5AC2
- OR3A3
- OR2W6P
- OR1A1
- OR16-89
- OR16-37
- OR11G2
- 6M1-16
- OR5T1
- OR5P2
- OR5M9
- OR5D18
- OR5B12
- OR2L3
- OR13H1
- OR13D1
- OR10W1
- OR10J5
- OR10A5
- OR2W3
- OR1D5
- OR9Q2
- OR8K1
- OR8D1
- OR7G3
- OR7D4
- OR6C70
- OR3A1
- OR2T1
- OR1C1
- OR16-90
- OR16-88
- OR11L1
- OR11H7
- OR10Z1
- OR10R2
- OR10A2
- OR5T2
- OR5P3
- OR5M11
- OR5J2
- OR5E1P
- OR2L8
- OR2H1
- OR2A12
- OR1D4
- OR13J1
- OR13C2
- OR10H4
- OR10H3
- OR10AG1
- OR6S1
- OR6J1
- OR6M1
- OR6C75
- OR6C3
- OR5H15
- OR5AL1
- OR2L2
- OR2AK2
- OR17-130
- OR13C3
- OR10A4
- JCG4
- OR5R1
- OR5M3
- OR5L1
- OR5AK2
- OR4F3
- OR4F29
- OR4F21
- OR4F16
- OR4C15
- OR2S2
- OR2M3
- OR1K1
- OR12D2
- OR11H4
- OR10V1
- OR10A6
- OR9I1
- OR9A4
- OR8H3
- OR6C6
- OR6C2
- OR6K3
- OR5K4
- OR5H1
- OR3A2
- OR2D3
- OR17-16
- OR17-137
- OR16-36
- OR10X1
- OR5W2
- OR4Q3
- OR4M1
- OR4K17
- OR2AP1
- OR2A2
- OR1F2P
- OR13C5
- OR13C4
- OR10K2
- OR10H5
- OR10H1
- olfr89
- OR8S1
- OR8K3
- OR8G5
- OR8D4
- OR8B4
- OR7-140
- OR7-139
- OR5D16
- OR5B17
- OR4S2
- OR4Q2
- OR2T6
- OR2T11
- OR2M2
- OR1F12
- OR17-15
- OR10J1
- OLFR 42A
- OR5M8
- OR4K14
- OR4D11
- OR4B1
- OR2T12
- OR2L13
- OR2F1
- OR1N1
- OR1A2
- OR10P1
- OR10H2
- OR10G2
- OR8G2
- OR2AG2
- OR8H1
- OR7D2
- OR6C65
- OR6C1
- OR4A15
- OR3A4P
- OR2V1
- OR2M5
- OR2H2
- OR11H12
- OR11H1
- OR5L2
- OR5D14
- OR4F15
- OR2T33
- OR2L5
- OR2A14
- OR1E3P
- OR10J6P
- OR5H14
- OR4A47
- OR2A1
- OR7C1
- OR7A2P
- OR9A1P
- OR8D2
- OR7E24
- OR6K6
- OR4E1
- OR4C6
- OR4A5
- OR2W5
- OR2A7
- OR1P1
- OR1E3
- OR10G6
- OR5K3
- OR5C1
- OR4M2
- OR4K13
- OR4F6
- OR4C46
- OR2Y1
- OR2J4P
- OR2F2
- OR2A42
- OR2A4
- OR1Q1
- FKSG35
- OR7A5
- OR4N2
- OR7G2
- OR7C2
- OR6T1
- OR9G9
- OR9G1
- OR4N4
- OR4K15
- OR4C3
- OR2V2
- OR2T8
- OR2T7
- OR2T35
- OR2T27
- OR2T2
- OR2T10
- OR2AJ1
- OR14L1P
- OR14C36
- OR11H2
- OR10J3
- OR5T3
- OR5D13
- OR4P4
- OR4K5
- OR4K2
- OR4K1
- OR4E2
- OR4D2
- OR4D1
- OR4A4P
- OR2M7
- OR2AE1
- OR1N2
- OR1I1
- OR12D3
- OR10G4
- OR7G1
- OR6C68
- OR5H6
- OR5D3
- OR4K3
- OR2H5P
- OR2C1
- OR2AT4
- OR1B1
- OR13A1
- OR11H13P
- OR10AD1
- OR5M10
- OR4L1
- OR4F5
- OR4F4
- OR4F17
- OR4D9
- OR4D5
- OR4D10
- OR2AG1
- OR10G9
- OR10G3
- OR9A2
- OR7E35P
- OR4C45
- OR14A16
- OR10S1
- OLFR 42B
- OR5M1
- OR4C5
- OR2I1P
- OR10G7
- OR10D4P
- tpcr110
- OR7A10
- OR6K2
- OR52E2
- OR4X2
- OR14I1
- OR4X1
- OR4N5
- OR4C12
- OR2T4
- OR10D3
- OR7A17
- OR14A2
- OR10G8
- PJCG2
- OR7E5P
- OR7E85P
- OR52L1
- OR4C13
- OR4A8P
- OR2T5
- OR4S1
- OR2T29
- OR14J1
- OR2T34
- OR2T3
- OR10AC1P
- OR2Z1
- OR14K1
- OR7E18P
- OR52L2P
- OR52K2
- OR52K1
- OR4D6
- OR56A4
- OR52Z1
- OR52I2
- OR52E8
- OR4C16
- OR4A16
- OR56B4
- OR56B2P
- OR56A3
- OR52K3P
- OR52E1
- OR4C11
- OR52R1
- OR52J3
- OR56B1
- OR52E6
- OR52E4
- OR51F1
- OR56A5
- OR52N5
- OR51B5
- OR51B4
- OR52W1
- OR52D1
- OR51L1
- OR51H1P
- OR51G2
- OR56A1
- OR56B3P
- OR52M1
- OR52H1
- OR52B2
- OR51I1
- OR51G1
- OR51F2
- OR51D1
- OR51B6
- OR51A1P
- OR52N2
- OR52E5
- OR51B2
- OR51A7
- OR52P1P
- OR52N1
- OR52I1
- OR52A5
- OR51V1
- OR51E2
- OR51A4
- OR51M1
- OR52N4
- OR52B6
- OR51T1
- OR51E1
- OR52B4
- OR51I2
- OR52A1
- OR51S1
- OR51A2
Variants for OR6B3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OR6B3 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs13030992 | Benign: not provided | 240,045,930(-) |
G/A NM_173351.1(OR6B3):c.143C>T (p.Thr48Ile) |
MISSENSE | |
| rs57303374 | Likely Benign: not provided | 240,045,743(-) |
G/A NM_173351.1(OR6B3):c.330C>T (p.Thr110=) |
SYNONYMOUS | |
| rs12465491 | -- |
p.Cys234Tyr |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
95.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.56;
65.03% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OR6B3 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR6B3 Gene
Disorders for OR6B3 Gene
Additional Disease Information for OR6B3
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for OR6B3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR6B3 Gene
Publications for OR6B3 Gene
- The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
- FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. (PMID: 29348145) Fung E … D'Angiolella V (EMBO reports 2018) 3
- The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M … Gstaiger M (Cell reports 2013) 3
- Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation. (PMID: 21244100) Virok DP … Fülöp L (Journal of proteome research 2011) 3
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
ExternalLinks
Products for OR6B3 Gene
- Custom Antibody ServicesOriGene Antibodies for OR6B3
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR6B3
- Origene Custom Protein Services for OR6B3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR6B3
- Browse OriGene Inhibitory RNA Products For OR6B3
- OriGene qPCR primer pairs for OR6B3
- OriGene CRISPR knockouts for OR6B3
- OriGene ORF clones in human for OR6B3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For OR6B3
- Sino Biological Human cDNA Clone for OR6B3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals proteins for OR6B3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for OR6B3 (AFLGC-OR6B3)
- VectorBuilder Custom and pre-made DNA vectors for OR6B3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OR6B3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OR6B3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OR6B3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OR6B3
- antibodies-online: Show 3 available OR6B3 Antibodies ranked by validation data
- Compare Top OR6B3 Antibodies
- Quality Products:
- antibodies-online: Show 10 available OR6B3 Elisa Kits ranked by validation data
- Compare Top OR6B3 Elisa Kits
- antibodies-online: Show 3 available OR6B3 Proteins ranked by validation data
- Compare Top OR6B3 Proteins
- Quality Products:
- Horizon Cell Lines for OR6B3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR6B3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR6B3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OR6B3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR6B3
- Boster Bio Antibodies for OR6B3
- Browse Boster Bio ELISA Kits
Sources for OR6B3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources