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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...
Aliases for OR5L2 Gene
Aliases for OR5L2 Gene
External Ids for OR5L2 Gene
- HGNC: 8351
- Entrez Gene: 26338
- Ensembl: ENSG00000205030
- UniProtKB: Q8NGL0
- HORDE: OR5L2
Previous GeneCards Identifiers for OR5L2 Gene
- GC11P057988
- GC11U900022
- GC11P055845
- GC11P055371
- GC11P055351
- GC11P055594
Summaries for OR5L2 Gene
-
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
GeneCards Summary for OR5L2 Gene
OR5L2 (Olfactory Receptor Family 5 Subfamily L Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and odorant binding. An important paralog of this gene is OR5L1.
UniProtKB/Swiss-Prot Summary for OR5L2 Gene
-
Odorant receptor.
Additional gene information for OR5L2 Gene
- HGNC(8351)
- Entrez Gene(26338)
- Ensembl(ENSG00000205030)
- UniProtKB(Q8NGL0)
- Open Targets Platform(ENSG00000205030)
- Search for OR5L2 at DataMed
- Search for OR5L2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR5L2 Gene
Genomics for OR5L2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OR5L2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11J055430 | Enhancer | 0.2 | FANTOM5 | 14.7 | -396.9 | -396888 | 0 | OR4A10P piR-31432-087 lnc-OR4A15-1 lnc-OR4A15-2 piR-40154-027 piR-52261-044 piR-49423-041 OR5D14 OR5D18 OR4C15 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OR5L2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OR5L2
- Top Transcription factor binding sites by QIAGEN in the OR5L2 gene promoter:
-
- Chx10
- Lmo2
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- Nkx3-1 v3
- Nkx3-1 v4
- STAT3
Genomic Locations for OR5L2 Gene
Genomic Locations for OR5L2 Gene
- chr11:55,827,219-55,828,154
- (GRCh38/hg38)
- Size:
- 936 bases
- Orientation:
- Plus strand
- chr11:55,594,695-55,595,630
- (GRCh37/hg19)
- Size:
- 936 bases
- Orientation:
- Plus strand
Genomic View for OR5L2 Gene
Genes around OR5L2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q12.1 by HGNC
- 11q12.1 by Entrez Gene
- 11q12.1 by Ensembl
OR5L2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR5L2 Gene
Proteins for OR5L2 Gene
-
Protein details for OR5L2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NGL0-OR5L2_HUMAN
- Recommended name:
- Olfactory receptor 5L2
- Protein Accession:
- Q8NGL0
- Q6IF66
- Q96RB2
Protein attributes for OR5L2 Gene
- Size:
- 311 amino acids
- Molecular mass:
- 34682 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for OR5L2 Gene
Other Protein References for OR5L2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
- HORDE protein sequence:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for OR5L2
- Invitrogen Antibodies for OR5L2 (AFLGC-OR5L2)
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR5L2
- Origene Custom Protein Services for OR5L2
Assay Products
No data available for DME Specific Peptides for OR5L2 Gene
Domains & Families for OR5L2 Gene
Gene Families for OR5L2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for OR5L2 Gene
- InterPro:
- Blocks:
-
- Olfactory receptor signature
- ProtoNet:
Suggested Antigen Peptide Sequences for OR5L2 Gene
- GenScript: Design optimal peptide antigens:
-
- Olfactory receptor OR11-153 (OR5L2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8NGL0- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR5L2 Gene
Molecular function for OR5L2 Gene
- UniProtKB/Swiss-Prot Function:
- Odorant receptor.
Phenotypes From GWAS Catalog for OR5L2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | IBA | -- |
| GO:0005549 | odorant binding | IBA | -- |
Phenotypes for OR5L2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR5L2 - Select products 50% OFF >
- * OR5L2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR5L2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR5L2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR5L2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR5L2
- Browse OriGene Inhibitory RNA Products For OR5L2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR5L2
Clone Products
- Applied Biological Materials (abm): Clones for OR5L2 - Select products 50% OFF >
- * OR5L2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR5L2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR5L2
Cell Line Products
-
Horizon Cell Lines for OR5L2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5L2 Gene
Localization for OR5L2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR5L2 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR5L2 Gene
Pathways & Interactions for OR5L2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory transduction | ||
Pathways by source for OR5L2 Gene
4 Reactome pathways for OR5L2 Gene
1 KEGG pathway for OR5L2 Gene
Interacting Proteins for OR5L2 Gene
GPS-Prot Interaction Network for OR5L2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | IBA | -- |
| GO:0007608 | sensory perception of smell | IBA | -- |
| GO:0050896 | response to stimulus | IEA | -- |
| GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
No data available for SIGNOR curated interactions for OR5L2 Gene
Transcripts for OR5L2 Gene
mRNA/cDNA for OR5L2 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000378397 936 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR5L2 - Select products 50% OFF >
- * OR5L2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR5L2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR5L2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR5L2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR5L2
- Browse OriGene Inhibitory RNA Products For OR5L2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR5L2
Clone Products
- Applied Biological Materials (abm): Clones for OR5L2 - Select products 50% OFF >
- * OR5L2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR5L2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR5L2
Relevant External Links for OR5L2 Gene
- GeneLoc Exon Structure for
- OR5L2
Expression for OR5L2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR5L2
SOURCE GeneReport for Unigene cluster for OR5L2 Gene:
Hs.528356Primer Products
-
OriGene qPCR primer pairs for OR5L2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR5L2 Gene
Orthologs for OR5L2 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC466540 30 |
|
||
| OR5L2 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | -- 31 |
|
ManyToMany | |
| Cow (Bos Taurus) |
Mammalia | OR5L2 30 |
|
||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| Mouse (Mus musculus) |
Mammalia | Olfr1157 31 |
|
OneToMany | |
| Olfr1156 30 17 |
|
||||
| Rat (Rattus norvegicus) |
Mammalia | Olr601 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany |
- Species where no ortholog for OR5L2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for OR5L2 Gene
- ENSEMBL:
- Gene Tree for OR5L2 (if available)
- TreeFam:
- Gene Tree for OR5L2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for OR5L2: view image
Paralogs for OR5L2 Gene
Paralogs for OR5L2 Gene
- OR5L1 5
- OR5D18 5
- OR5D16 5
- OR5D14 5
- OR5I1 5
- OR5D3P 5
- OR5D13 5
- OR5AP2 5
- OR8J1 5
- OR5AU1 5
- OR5B21 5
- OR5W2 5
- OR5F1 5
- OR8J3 5
- OR5J2 5
- OR9I1 5
- OR8D1 5
- OR5B12 5
- OR8U1 5
- OR5M8 5
- OR5M11 5
- OR5M1 5
- OR5AR1 5
- OR5A2 5
- OR5A1 5
- OR5M10 5
- OR9G4 5
- OR5P3 5
- OR8D4 5
- OR8G1 5
- OR8I2 5
- OR8H3 5
- OR5C1 5
- OR8J2 5
- OR8H1 5
- OR5R1 5
- OR5B3 5
- OR8G5 5
- OR8D2 5
- OR8B2 5
- OR8B3 5
- OR8A1 5
- OR5AN1 5
- OR5AS1 5
- OR8K5 5
- OR8K3 5
- OR9K2 5
- OR9Q2 5
- OR5B2 5
- OR8B4 5
- OR8B8 5
- OR9H1P 5
- OR8H2 5
- OR8K1 5
- ENSG00000284732 5
- OR5M3 5
- OR5M9 5
- OR5AK2 5
- OR5P2 5
- OR5B17 5
- OR8B12 5
- OR5H2 5
- OR5K3 5
- OR5K4 5
- OR5K1 5
- OR9Q1 5
- OR5AC2 5
- OR5K2 5
- OR6B2 5
- OR6Q1 5
- OR11L1 5
- OR5H6 5
- OR6B3 5
- OR5H1 5
- OR5H14 5
- OR13A1 5
- OR10Q1 5
- OR5H15 5
- OR6P1 5
- OR14J1 5
- OR10V1 5
- OR14A2 5
- OR14A16 5
- OR14I1 5
- OR10H4 5
- OR10W1 5
- OR14K1 5
- OR14C36 5
- OR10H3 5
- OR5H8 5
- OR5AL1 5
- OR5G3 5
- OR5AC1 5
(446) SIMAP similar genes for OR5L2 Gene using alignment to 1 proteins:
- OR5L2_HUMAN
- OR5L1
- OR5D18
- OR5B2
- OR8U9
- OR8U1
- OR5B12
- OR5F1
- OR8U8
- OR5D16
- OR5A2
- OR5I1
- OR8G1
- OR8D4
- OR5R1
- OR5M11
- OR5D13
- OR5B3
- OR5B21
- OR5AS1
- OR5AR1
- OR8J3
- OR8G2
- OR9K2
- OR9I1
- OR8K1
- OR8J1
- OR8D1
- OR5W2
- OR5T1
- OR5D14
- OR5B17
- OR5AL1
- OR9Q1
- OR8G5
- OR8B3
- OR9Q2
- OR9G4
- OR8J2
- OR8H2
- OR8D2
- OR8B2
- OR8A1
- OR5T3
- OR5T2
- OR5M3
- OR5G3
- OR5D3
- OR5C1
- OR5AK3P
- OR5AC1
- OR5A1
- OR5J2
- OR8K5
- OR8H3
- OR8B8
- OR5V1
- OR5M1
- OR8K3
- OR8I2
- OR6M1
- OR6C68
- OR6C4
- OR5M9
- OR5M8
- OR5M10
- OR5K1
- OR5E1P
- OR5AP2
- OR5AK2
- OR2T10
- OR2D3
- OR2G3
- OR2B6
- OR13C2
- OR8H1
- OR8B12
- OR9G9
- OR9G1
- OR6S1
- OR6N2
- OR6N1
- OR6C3
- OR6C1
- OR5K4
- OR5K3
- OR5K2
- OR5AC2
- OR4Q3
- OR4Q2
- OR4B1
- OR2K2
- OR2G6
- OR2B8P
- OR2AP1
- OR1L8
- OR1L6
- OR13G1
- OR10R2
- OR10J1
- OR2B3
- OR2B2
- OR13C9
- FKSG35
- OR6C74
- OR7D2
- OR6Y1
- OR6C70
- OR6C6
- OR6C2
- OR5H2
- OR5AU1
- OR5AN1
- OR4S2
- OR2W6P
- OR2C3
- OR2B11
- OR2A12
- OR1P1
- OR1L4
- OR1L1
- OR1F2P
- OR1F1
- OR1C1
- OR13D1
- OR13C5
- OR10S1
- OR10K1
- JCG4
- OR1M1
- OR1G1
- OR12D3
- OR11A1
- OR10R3P
- OR11L1
- OR10C1
- OR8S1
- OR8B4
- OR7G1
- OR6P1
- OR6C76
- OR6C75
- OR6C65
- OR5P2
- OR4E1
- OR2W3
- OR2T33
- OR2T11
- OR2J4P
- OR2F1
- OR2AK2
- OR1S2
- OR1S1
- OR1L3
- OR1J4
- OR1J1
- OR1E1
- OR1D2
- OR16-36
- OR13C3
- OR13A1
- OR10V1
- OR10T2
- OR10J4
- OR10AG1
- OR10A7
- OR10A2
- OR4E2
- OR4D2
- OR2W1
- OR2S2
- OR2D2
- OR1J2
- OR10Q1
- OR10J5
- OR10A3
- OR7A5
- OR6Q1
- OLFR 42A
- OR2L8
- OR7C1
- OR7A17
- OR7A10
- OR7A2P
- OR6X1
- OR5H6
- OR5H1
- OR4X1
- OR4D11
- OR4D10
- OR4C46
- OR4C15
- OR4C13
- OR4A15
- OR3A3
- OR3A1
- OR2Y1
- OR2T8
- OR2T7
- OR2T2
- OR2T12
- OR2T1
- OR2L5
- OR2L3
- OR2L2
- OR2J1
- OR2H2
- OR2G2
- OR2C1
- OR2A5
- OR1N2
- OR1K1
- OR1F12
- OR1A1
- OR17-16
- OR17-137
- OR17-130
- OR16-90
- OR16-89
- OR16-88
- OR16-37
- OR14A2
- OR11H7
- OR11H4
- OR11G2
- OR10Z1
- OR10W1
- OR10G9
- OR10G8
- OR10G7
- OR10G2
- OR10A5
- OR10A4
- OR4D1
- OR2J3
- OR2A2
- OR1Q1
- OR13C4
- OR10H2
- OR13F1
- OR10K2
- OR2F2
- OR2A1
- OR9A4
- OR5P3
- PJCG1
- OR7G3
- OR7D4
- OR7C2
- OR6K3
- OR6F1
- OR4X2
- OR4N5
- OR4K3
- OR4F15
- OR4C3
- OR4C12
- OR4A4P
- OR4A47
- OR3A4P
- OR3A2
- OR2W5
- OR2T5
- OR2T4
- OR2T35
- OR2T29
- OR2T27
- OR2M4
- OR2M3
- OR2M2
- OR2H5P
- OR2A42
- OR1D4
- OR14A16
- OR13H1
- OR13C8
- OR11H6
- OR11H2
- OR11H12
- OR11H1
- OR10J3
- OR10G6
- OR10D4P
- 6M1-16
- OR4M1
- OR2J2
- OR2AG1
- OR2AE1
- OR1I1
- OR1E2
- OR1D5
- OR12D2
- OR10H4
- OR10H3
- OR10G4
- OR10A6
- OR2A14
- OR6V1
- OR7E24
- OR6K2
- OR6J1
- OR6B2
- OR5H15
- OR5H14
- OR4M2
- OR4K2
- OR4F6
- OR4F5
- OR4D9
- OR4D6
- OR4C6
- OR2V2
- OR2V1
- OR2M7
- OR2M5
- OR2L13
- OR2AJ1
- OR2A7
- OR2A25
- OR1N1
- OR10X1
- OR10P1
- OR10H5
- OR10G3
- HSA10
- OR4S1
- OR4L1
- OR4D5
- OR2H1
- OR2A4
- OR10H1
- OR6B3
- OR2AG2
- OR6B1
- OR6A2
- olfr89
- OR6K6
- OR4N4
- OR4K17
- OR4K15
- OR4K13
- OR4K1
- OR4F4
- OR4F21
- OR4F17
- OR4C5
- OR2Z1
- OR2T3
- OR1E3
- OR17-15
- OR14L1P
- OR13J1
- OR10J6P
- OR10D3
- OR10AD1
- OLFR 42B
- OR4F3
- OR4F29
- OR4F16
- OR1A2
- OR14J1
- OR4N2
- OR6T1
- OR9A2
- OR7G2
- OR7-140
- OR7-139
- OR4P4
- OR4K5
- OR4K14
- OR4C45
- OR4C11
- OR4A8P
- OR4A5
- OR2T6
- OR2T34
- OR1B1
- OR14I1
- OR14C36
- OR1E3P
- OR9A1P
- OR7E85P
- OR7E35P
- OR7E5P
- OR52K1
- OR4C16
- OR4A16
- OR52K2
- OR2AT4
- OR14K1
- OR11H13P
- OR2I1P
- OR10AC1P
- OR52R1
- OR52N2
- OR52J3
- OR52E8
- OR52E2
- OR52B6
- OR51D1
- OR51I1
- OR56B2P
- OR56A4
- OR52N5
- OR52N4
- OR52M1
- OR52L1
- OR52E4
- OR51E2
- OR51M1
- OR51H1P
- OR56A5
- OR52Z1
- OR52N1
- OR52L2P
- OR52I2
- OR52H1
- OR52E6
- OR51T1
- OR51L1
- OR51G1
- OR51F1
- OR51E1
- OR51B4
- OR51B2
- OR52D1
- OR52A5
- OR56B4
- OR56A1
- OR52I1
- OR52E5
- OR52B1P
- OR52A1
- OR51F2
- OR51B5
- OR52E1
- OR56B1
- OR56A3
- OR52P1P
- OR52B4
- OR52B2
- OR51G2
- OR51B6
- OR51A7
- OR51V1
- OR51I2
- OR51A4
Variants for OR5L2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OR5L2 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs17148058 | - | p.Met81Arg | |||
| rs56711116 | - | p.Val59Met |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1193n100 | CNV | loss | 25217958 |
| dgv1204n100 | CNV | loss | 25217958 |
| dgv1205n100 | CNV | gain | 25217958 |
| dgv12n64 | CNV | loss | 17921354 |
| dgv150n27 | CNV | loss | 19166990 |
| dgv1905n54 | CNV | gain | 21841781 |
| dgv1941n54 | CNV | loss | 21841781 |
| dgv212e199 | CNV | deletion | 23128226 |
| dgv50e55 | CNV | loss | 17911159 |
| dgv51e55 | CNV | loss | 17911159 |
| esv22842 | CNV | gain+loss | 19812545 |
| esv2744537 | CNV | deletion | 23290073 |
| esv2751030 | CNV | gain | 17911159 |
| esv2759828 | CNV | gain+loss | 17122850 |
| esv2760216 | CNV | loss | 21179565 |
| esv3579771 | CNV | gain | 25503493 |
| esv3579782 | CNV | gain | 25503493 |
| esv3626453 | CNV | loss | 21293372 |
| esv3626454 | CNV | gain | 21293372 |
| esv3626456 | CNV | loss | 21293372 |
| nsv1044174 | CNV | loss | 25217958 |
| nsv39282 | CNV | deletion | 16902084 |
| nsv428256 | CNV | loss | 18775914 |
| nsv437717 | CNV | loss | 16327808 |
| nsv469885 | CNV | loss | 16826518 |
| nsv469958 | CNV | loss | 18288195 |
| nsv517440 | CNV | gain+loss | 19592680 |
| nsv554801 | CNV | loss | 21841781 |
| nsv821668 | CNV | loss | 15273396 |
| nsv832158 | CNV | gain | 17160897 |
| nsv972027 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
86.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.85;
79.32% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OR5L2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- OR5L2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5L2 Gene
Disorders for OR5L2 Gene
Additional Disease Information for OR5L2
No disorders were found for OR5L2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5L2 Gene
Publications for OR5L2 Gene
- Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M … Perret J (Nature 1992) 2 3 4
- The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
- DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
ExternalLinks
Products for OR5L2 Gene
- Custom Antibody ServicesOriGene Antibodies for OR5L2
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR5L2
- Origene Custom Protein Services for OR5L2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR5L2
- Browse OriGene Inhibitory RNA Products For OR5L2
- OriGene qPCR primer pairs for OR5L2
- OriGene CRISPR knockouts for OR5L2
- OriGene ORF clones in human for OR5L2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For OR5L2
- Sino Biological Human cDNA Clone for OR5L2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Invitrogen Antibodies for OR5L2 (AFLGC-OR5L2)
- VectorBuilder Custom and pre-made DNA vectors for OR5L2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OR5L2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OR5L2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OR5L2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OR5L2
- antibodies-online: Show 10 available OR5L2 Antibodies ranked by validation data
- Compare Top OR5L2 Antibodies
- antibodies-online: Show 10 available OR5L2 Elisa Kits ranked by validation data
- Compare Top OR5L2 Elisa Kits
- antibodies-online: Search results for available OR5L2 related products ranked by validation data
- Horizon Cell Lines for OR5L2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR5L2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR5L2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OR5L2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR5L2
Sources for OR5L2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB