Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR5AK3P Gene

Aliases for OR5AK3P Gene

  • Olfactory Receptor Family 5 Subfamily AK Member 3 Pseudogene 2 3 5
  • OR5AK3 3 4
  • Olfactory Receptor, Family 5, Subfamily AK, Member 3 Pseudogene 2
  • Putative Olfactory Receptor 5AK3 4
  • Olfactory Receptor 5AK3 3
  • OR5AK3P 5

External Ids for OR5AK3P Gene

Previous HGNC Symbols for OR5AK3P Gene

  • OR5AK3

Previous GeneCards Identifiers for OR5AK3P Gene

  • GC11U900578
  • GC11P056495
  • GC11P056738

Summaries for OR5AK3P Gene

Entrez Gene Summary for OR5AK3P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5AK3P Gene

OR5AK3P (Olfactory Receptor Family 5 Subfamily AK Member 3 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5AK2.

UniProtKB/Swiss-Prot Summary for OR5AK3P Gene

Additional gene information for OR5AK3P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR5AK3P Gene

Genomics for OR5AK3P Gene

Genomic Locations for OR5AK3P Gene

Latest Assembly
chr11:56,971,050-56,971,979
(GRCh38/hg38)
Size:
930 bases
Orientation:
Plus strand

Previous Assembly
chr11:56,738,526-56,739,452
(GRCh37/hg19 by Entrez Gene)
Size:
927 bases
Orientation:
Plus strand

chr11:56,738,325-56,739,621
(GRCh37/hg19 by Ensembl)
Size:
1,297 bases
Orientation:
Plus strand

Genomic View for OR5AK3P Gene

Genes around OR5AK3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5AK3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5AK3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5AK3P Gene

No data available for GeneHancer (GH) Regulatory Elements for OR5AK3P Gene

Proteins for OR5AK3P Gene

  • Protein details for OR5AK3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH89-O5AK3_HUMAN
    Recommended name:
    Putative olfactory receptor 5AK3
    Protein Accession:
    Q8NH89

    Protein attributes for OR5AK3P Gene

    Size:
    298 amino acids
    Molecular mass:
    33542 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5AK3P Gene

Post-translational modifications for OR5AK3P Gene

  • Glycosylation at Asn5, Asn155, and Asn265

Other Protein References for OR5AK3P Gene

ENSEMBL proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5AK3P Gene

Domains & Families for OR5AK3P Gene

Gene Families for OR5AK3P Gene

Protein Domains for OR5AK3P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR5AK3P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 5AK3 (O5AK3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NH89

UniProtKB/Swiss-Prot:

O5AK3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5AK3P: view

Function for OR5AK3P Gene

Molecular function for OR5AK3P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR5AK3P Gene

Gene Ontology (GO) - Molecular Function for OR5AK3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA 21873635
GO:0005549 odorant binding IBA 21873635
genes like me logo Genes that share ontologies with OR5AK3P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5AK3P Gene

Localization for OR5AK3P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5AK3P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR5AK3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5AK3P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR5AK3P Gene

Pathways & Interactions for OR5AK3P Gene

PathCards logo

SuperPathways for OR5AK3P Gene

genes like me logo Genes that share pathways with OR5AK3P: view

Pathways by source for OR5AK3P Gene

Gene Ontology (GO) - Biological Process for OR5AK3P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IBA 21873635
GO:0007608 sensory perception of smell IBA 21873635
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5AK3P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR5AK3P Gene

Drugs & Compounds for OR5AK3P Gene

No Compound Related Data Available

Transcripts for OR5AK3P Gene

mRNA/cDNA for OR5AK3P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5AK3P Gene

No ASD Table

Relevant External Links for OR5AK3P Gene

GeneLoc Exon Structure for
OR5AK3P

Expression for OR5AK3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR5AK3P Gene

mRNA differential expression in normal tissues according to GTEx for OR5AK3P Gene

This gene is overexpressed in Spleen (x46.0).
genes like me logo Genes that share expression patterns with OR5AK3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR5AK3P Gene

Orthologs for OR5AK3P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR5AK3P Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Or5ai1-ps 45 Olfr989-ps1
  • chr2:85,378,812-85,379,422
Or5ak23 45 Olfr993
  • chr2:85,413,936-85,414,877
Or5ak24 45 Olfr994
  • chr2:85,429,886-85,430,827
Or5ak25 45 Olfr995
  • chr2:85,438,212-85,439,156
Species where no ortholog for OR5AK3P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR5AK3P Gene

ENSEMBL:
Gene Tree for OR5AK3P (if available)
TreeFam:
Gene Tree for OR5AK3P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR5AK3P

Paralogs for OR5AK3P Gene

(444) SIMAP similar genes for OR5AK3P Gene using alignment to 1 proteins:

  • O5AK3_HUMAN
genes like me logo Genes that share paralogs with OR5AK3P: view

Variants for OR5AK3P Gene

Additional Variant Information for OR5AK3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR5AK3P
Leiden Open Variation Database (LOVD)
OR5AK3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR5AK3P Gene

Disorders for OR5AK3P Gene

No disorders were found for OR5AK3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR5AK3P Gene

Publications for OR5AK3P Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR5AK3P Gene

Sources for OR5AK3P Gene