Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR56B2P Gene

Aliases for OR56B2P Gene

  • Olfactory Receptor Family 56 Subfamily B Member 2 Pseudogene 2 3 5
  • Olfactory Receptor, Family 56, Subfamily B, Member 2 2 3
  • Olfactory Receptor, Family 56, Subfamily B, Member 2 Pseudogene 2
  • Seven Transmembrane Helix Receptor 3
  • Putative Olfactory Receptor 56B2 4
  • Olfactory Receptor OR11-63 3
  • Olfactory Receptor 56B2 3
  • OR11-63 3
  • OR56B2P 5
  • OR56B2 3

External Ids for OR56B2P Gene

Previous HGNC Symbols for OR56B2P Gene

  • OR56B2

Previous GeneCards Identifiers for OR56B2P Gene

  • GC11P005749

Summaries for OR56B2P Gene

Entrez Gene Summary for OR56B2P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR56B2P Gene

OR56B2P (Olfactory Receptor Family 56 Subfamily B Member 2 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56B1.

UniProtKB/Swiss-Prot Summary for OR56B2P Gene

Additional gene information for OR56B2P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR56B2P Gene

Genomics for OR56B2P Gene

Genomic Locations for OR56B2P Gene

Latest Assembly
chr11:5,761,153-5,767,465
(GRCh38/hg38)
Size:
6,313 bases
Orientation:
Plus strand

Previous Assembly
chr11:5,786,391-5,787,275
(GRCh37/hg19 by Entrez Gene)
Size:
885 bases
Orientation:
Plus strand

chr11:5,786,326-5,787,279
(GRCh37/hg19 by Ensembl)
Size:
954 bases
Orientation:
Plus strand

Genomic View for OR56B2P Gene

Genes around OR56B2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR56B2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR56B2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56B2P Gene

No data available for GeneHancer (GH) Regulatory Elements for OR56B2P Gene

Proteins for OR56B2P Gene

  • Protein details for OR56B2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGI1-O56B2_HUMAN
    Recommended name:
    Putative olfactory receptor 56B2
    Protein Accession:
    Q8NGI1

    Protein attributes for OR56B2P Gene

    Size:
    322 amino acids
    Molecular mass:
    35955 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR56B2P Gene

Post-translational modifications for OR56B2P Gene

  • Glycosylation at Asn12

Other Protein References for OR56B2P Gene

ENSEMBL proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR56B2P Gene

Domains & Families for OR56B2P Gene

Gene Families for OR56B2P Gene

Protein Domains for OR56B2P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR56B2P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 56B2 (O56B2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGI1

UniProtKB/Swiss-Prot:

O56B2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56B2P: view

Function for OR56B2P Gene

Molecular function for OR56B2P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR56B2P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR56B2P Gene

Localization for OR56B2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56B2P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR56B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56B2P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR56B2P Gene

Pathways & Interactions for OR56B2P Gene

PathCards logo

SuperPathways for OR56B2P Gene

genes like me logo Genes that share pathways with OR56B2P: view

Pathways by source for OR56B2P Gene

Gene Ontology (GO) - Biological Process for OR56B2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR56B2P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR56B2P Gene

Drugs & Compounds for OR56B2P Gene

No Compound Related Data Available

Transcripts for OR56B2P Gene

mRNA/cDNA for OR56B2P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR56B2P Gene

No ASD Table

Relevant External Links for OR56B2P Gene

GeneLoc Exon Structure for
OR56B2P

Expression for OR56B2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR56B2P Gene

mRNA differential expression in normal tissues according to GTEx for OR56B2P Gene

This gene is overexpressed in Nerve - Tibial (x13.6), Adipose - Subcutaneous (x4.9), and Breast - Mammary Tissue (x4.0).
genes like me logo Genes that share expression patterns with OR56B2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR56B2P Gene

Orthologs for OR56B2P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR56B2P Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Or56b2 45 Olfr661
  • chr7:104,688,017-104,688,973
Or56b33 45 Olfr663
  • chr7:104,703,569-104,704,600
Species where no ortholog for OR56B2P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR56B2P Gene

ENSEMBL:
Gene Tree for OR56B2P (if available)
TreeFam:
Gene Tree for OR56B2P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR56B2P

Paralogs for OR56B2P Gene

(426) SIMAP similar genes for OR56B2P Gene using alignment to 1 proteins:

  • O56B2_HUMAN
genes like me logo Genes that share paralogs with OR56B2P: view

Variants for OR56B2P Gene

Additional Variant Information for OR56B2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR56B2P
Leiden Open Variation Database (LOVD)
OR56B2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR56B2P Gene

Disorders for OR56B2P Gene

No disorders were found for OR56B2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR56B2P Gene

Publications for OR56B2P Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3

Products for OR56B2P Gene

Sources for OR56B2P Gene