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Aliases for OR56B1 Gene

Aliases for OR56B1 Gene

  • Olfactory Receptor Family 56 Subfamily B Member 1 2 3 5
  • Olfactory Receptor OR11-65 3 4
  • OR56B1P 3 4
  • Olfactory Receptor, Family 56, Subfamily B, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily B, Member 1 2
  • Olfactory Receptor 56B1 3
  • OR11-65 3

External Ids for OR56B1 Gene

Previous HGNC Symbols for OR56B1 Gene

  • OR56B1P

Previous GeneCards Identifiers for OR56B1 Gene

  • GC11P005721
  • GC11P005715

Summaries for OR56B1 Gene

Entrez Gene Summary for OR56B1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR56B1 Gene

OR56B1 (Olfactory Receptor Family 56 Subfamily B Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56B4.

UniProtKB/Swiss-Prot for OR56B1 Gene

  • Odorant receptor.

Gene Wiki entry for OR56B1 Gene

Additional gene information for OR56B1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56B1 Gene

Genomics for OR56B1 Gene

GeneHancer (GH) Regulatory Elements for OR56B1 Gene

Promoters and enhancers for OR56B1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J005379 Enhancer 0.2 FANTOM5 8.3 -356.5 -356456 0 OR51V1 OR51T1 HBB OR51B5 OR51G1 OR56B1 OR52J3 OR51L1 OR52N4 OR52D1
GH11J005546 Enhancer 0.2 FANTOM5 3.6 -190.2 -190202 0.1 OR56A1 OR56A3 OR51Q1 OR52E8 OR52N1 OR56A4 OR52N4 OR52E2 OR52E4 OR52A1
GH11J005328 Enhancer 0.2 FANTOM5 1.3 -407.3 -407270 0.4 OR51G1 OR51T1 OR52N2 OR52N4 OR52D1 OR52J3 MMP26 OR51L1 OR51B2 OR51M1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around OR56B1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR56B1 gene promoter:
  • Max
  • c-Myc
  • CUTL1
  • Tal-1beta
  • ITF-2
  • HNF-1
  • HNF-1A
  • Pax-4a
  • HOXA9
  • HOXA9B

Genomic Locations for OR56B1 Gene

Genomic Locations for OR56B1 Gene
2,075 bases
Plus strand
1,091 bases
Plus strand

Genomic View for OR56B1 Gene

Genes around OR56B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR56B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR56B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56B1 Gene

Proteins for OR56B1 Gene

  • Protein details for OR56B1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 56B1
    Protein Accession:
    Secondary Accessions:
    • B2RNY6
    • B3KV42
    • Q6IF76

    Protein attributes for OR56B1 Gene

    324 amino acids
    Molecular mass:
    36050 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC06031.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR56B1 Gene

Post-translational modifications for OR56B1 Gene

Other Protein References for OR56B1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for OR56B1

No data available for DME Specific Peptides for OR56B1 Gene

Domains & Families for OR56B1 Gene

Gene Families for OR56B1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR56B1 Gene

Suggested Antigen Peptide Sequences for OR56B1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56B1: view

Function for OR56B1 Gene

Molecular function for OR56B1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR56B1: view
genes like me logo Genes that share phenotypes with OR56B1: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR56B1 Gene

Localization for OR56B1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56B1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR56B1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR56B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA,TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56B1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR56B1 Gene

Pathways & Interactions for OR56B1 Gene

genes like me logo Genes that share pathways with OR56B1: view

Pathways by source for OR56B1 Gene

Interacting Proteins for OR56B1 Gene

Gene Ontology (GO) - Biological Process for OR56B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IBA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR56B1: view

No data available for SIGNOR curated interactions for OR56B1 Gene

Drugs & Compounds for OR56B1 Gene

No Compound Related Data Available

Transcripts for OR56B1 Gene

mRNA/cDNA for OR56B1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR56B1 Gene

Olfactory receptor, family 56, subfamily B, member 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR56B1 Gene

No ASD Table

Relevant External Links for OR56B1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR56B1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR56B1 Gene

Protein differential expression in normal tissues from HIPED for OR56B1 Gene

This gene is overexpressed in CD4 Tcells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OR56B1 Gene

Protein tissue co-expression partners for OR56B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR56B1 Gene:


SOURCE GeneReport for Unigene cluster for OR56B1 Gene:

genes like me logo Genes that share expression patterns with OR56B1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR56B1 Gene

Orthologs for OR56B1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56B1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466391 33
  • 99.07 (n)
OR56B1 34
  • 98 (a)
(Canis familiaris)
Mammalia LOC100684837 33
  • 83.9 (n)
OR56B1 34
  • 83 (a)
(Mus musculus)
Mammalia Or56b1 51 Olfr657 16 34 33
  • 83.6 (n)
Or56b1b 51 Olfr504 34
  • 79 (a)
Or56b36-ps 51 Olfr660-ps1
  • chr7:104,678,730-104,679,095
(Rattus norvegicus)
Mammalia LOC100910597 33
  • 83.44 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 76 (a)
-- 34
  • 76 (a)
(Bos Taurus)
Mammalia -- 34
  • 71 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 69 (a)
-- 34
  • 66 (a)
-- 34
  • 65 (a)
-- 34
  • 63 (a)
-- 34
  • 63 (a)
-- 34
  • 52 (a)
Species where no ortholog for OR56B1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56B1 Gene

Gene Tree for OR56B1 (if available)
Gene Tree for OR56B1 (if available)
Evolutionary constrained regions (ECRs) for OR56B1: view image

Paralogs for OR56B1 Gene

Paralogs for OR56B1 Gene

(422) SIMAP similar genes for OR56B1 Gene using alignment to 1 proteins:

  • O56B1_HUMAN
genes like me logo Genes that share paralogs with OR56B1: view

Variants for OR56B1 Gene

Sequence variations from dbSNP and Humsavar for OR56B1 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000613958 -- 5,734,935(+) T/A/C upstream_transcript_variant
rs1000645328 -- 5,735,242(+) G/C upstream_transcript_variant
rs1000672625 -- 5,737,737(+) A/G downstream_transcript_variant
rs1001189680 -- 5,737,990(+) T/A downstream_transcript_variant
rs1001277516 -- 5,737,840(+) T/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR56B1 Gene

Variant ID Type Subtype PubMed ID
esv2759801 CNV gain+loss 17122850
esv989880 CNV deletion 20482838
nsv1041568 CNV loss 25217958
nsv1046068 CNV gain 25217958
nsv1053414 CNV gain 25217958
nsv553241 CNV gain 21841781
nsv553273 CNV gain 21841781
nsv553277 CNV gain 21841781
nsv832058 CNV gain 17160897

Variation tolerance for OR56B1 Gene

Residual Variation Intolerance Score: 90.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.94; 59.64% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR56B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR56B1 Gene

Disorders for OR56B1 Gene

Additional Disease Information for OR56B1

No disorders were found for OR56B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR56B1 Gene

Publications for OR56B1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. (PMID: 17567994) Denoeud F … Reymond A (Genome research 2007) 3 58
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4 58
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for OR56B1 Gene

Sources for OR56B1 Gene

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