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Aliases for OR56A5 Gene

Aliases for OR56A5 Gene

  • Olfactory Receptor Family 56 Subfamily A Member 5 2 3 5
  • OR56A5P 3 4
  • Olfactory Receptor, Family 56, Subfamily A, Member 5 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily A, Member 5 2
  • Olfactory Receptor 56A5 3

External Ids for OR56A5 Gene

Previous HGNC Symbols for OR56A5 Gene

  • OR56A5P

Previous GeneCards Identifiers for OR56A5 Gene

  • GC11U900569
  • GC11M005946
  • GC11M005949

Summaries for OR56A5 Gene

Entrez Gene Summary for OR56A5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Mar 2009]

GeneCards Summary for OR56A5 Gene

OR56A5 (Olfactory Receptor Family 56 Subfamily A Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56A4.

UniProtKB/Swiss-Prot for OR56A5 Gene

  • Odorant receptor.

Additional gene information for OR56A5 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A5 Gene

Genomics for OR56A5 Gene

GeneHancer (GH) Regulatory Elements for OR56A5 Gene

Promoters and enhancers for OR56A5 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J005546 Enhancer 0.2 FANTOM5 8.7 +422.2 422248 0.1 OR56A1 OR56A3 OR51Q1 OR52E8 OR52N1 OR56A4 OR52N4 OR52E2 OR52E4 OR52A1
GH11J006094 Enhancer 0.2 FANTOM5 1.4 -125.9 -125925 0.1 OR56A1 OR52W1 FAM160A2 C11orf42 TRIM5 TRIM34 OR52N1 OR56A3 OR52E8 TRIM22
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR56A5 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR56A5 gene promoter:
  • STAT5A
  • Pax-6
  • AML1a
  • USF-1
  • HNF-4alpha2
  • HNF-4alpha1
  • USF1
  • GATA-1
  • HEN1

Genomic Locations for OR56A5 Gene

Genomic Locations for OR56A5 Gene
1,318 bases
Minus strand
1,318 bases
Minus strand

Genomic View for OR56A5 Gene

Genes around OR56A5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR56A5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR56A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A5 Gene

Proteins for OR56A5 Gene

  • Protein details for OR56A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 56A5
    Protein Accession:

    Protein attributes for OR56A5 Gene

    313 amino acids
    Molecular mass:
    35317 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR56A5 Gene

Post-translational modifications for OR56A5 Gene

  • Glycosylation at Asn198, Asn184, Asn7, and Asn6

Other Protein References for OR56A5 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR56A5 Gene

Domains & Families for OR56A5 Gene

Gene Families for OR56A5 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR56A5 Gene

Suggested Antigen Peptide Sequences for OR56A5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56A5: view

Function for OR56A5 Gene

Molecular function for OR56A5 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go IBA --
GO:0004871 obsolete signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004935 NOT adrenergic receptor activity IBA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR56A5: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR56A5 Gene

Localization for OR56A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030672 synaptic vesicle membrane IBA --
genes like me logo Genes that share ontologies with OR56A5: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR56A5 Gene

Pathways & Interactions for OR56A5 Gene

genes like me logo Genes that share pathways with OR56A5: view

Pathways by source for OR56A5 Gene

Interacting Proteins for OR56A5 Gene

Gene Ontology (GO) - Biological Process for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001963 synaptic transmission, dopaminergic IBA --
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA --
GO:0007194 negative regulation of adenylate cyclase activity IBA --
genes like me logo Genes that share ontologies with OR56A5: view

No data available for SIGNOR curated interactions for OR56A5 Gene

Drugs & Compounds for OR56A5 Gene

No Compound Related Data Available

Transcripts for OR56A5 Gene

mRNA/cDNA for OR56A5 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR56A5 Gene

Olfactory receptor, family 56, subfamily A, member 5:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A5 Gene

ExUns: 1a · 1b ^ 2

Relevant External Links for OR56A5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR56A5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR56A5 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR56A5 Gene:


SOURCE GeneReport for Unigene cluster for OR56A5 Gene:

genes like me logo Genes that share expression patterns with OR56A5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR56A5 Gene

Orthologs for OR56A5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56A5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OR56A5 33
  • 99.47 (n)
(Canis familiaris)
Mammalia cOR56A24 33
  • 88.18 (n)
(Bos Taurus)
Mammalia OR56A4 33
  • 85.73 (n)
(Mus musculus)
Mammalia Or56a5 51 Olfr683 16 33
  • 85.42 (n)
(Rattus norvegicus)
Mammalia Olr192 33
  • 84.46 (n)
Species where no ortholog for OR56A5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56A5 Gene

Gene Tree for OR56A5 (if available)
Gene Tree for OR56A5 (if available)
Evolutionary constrained regions (ECRs) for OR56A5: view image

Paralogs for OR56A5 Gene

Paralogs for OR56A5 Gene

(429) SIMAP similar genes for OR56A5 Gene using alignment to 1 proteins:

  • O56A5_HUMAN
genes like me logo Genes that share paralogs with OR56A5: view

Variants for OR56A5 Gene

Sequence variations from dbSNP and Humsavar for OR56A5 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000610464 -- 5,967,838(-) G/A coding_sequence_variant, synonymous_variant
rs1000961430 -- 5,967,467(-) A/G downstream_transcript_variant
rs1001839470 -- 5,968,620(-) T/C upstream_transcript_variant
rs1003500856 -- 5,969,500(-) T/C upstream_transcript_variant
rs1003846448 -- 5,969,878(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR56A5 Gene

Variant ID Type Subtype PubMed ID
esv2759801 CNV gain+loss 17122850
nsv1046068 CNV gain 25217958
nsv1053414 CNV gain 25217958
nsv553241 CNV gain 21841781
nsv553277 CNV gain 21841781
nsv975875 CNV duplication 23825009

Additional Variant Information for OR56A5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OR56A5 Gene

Disorders for OR56A5 Gene

Additional Disease Information for OR56A5

No disorders were found for OR56A5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR56A5 Gene

Publications for OR56A5 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR56A5 Gene

Sources for OR56A5 Gene

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