Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR52L2P Gene

Aliases for OR52L2P Gene

  • Olfactory Receptor Family 52 Subfamily L Member 2 Pseudogene 2 3 5
  • Olfactory Receptor OR11-74 3 4
  • OR52L2 3 4
  • Olfactory Receptor, Family 52, Subfamily L, Member 2 Pseudogene 2
  • Seven Transmembrane Helix Receptor 3
  • Putative Olfactory Receptor 52L2 4
  • Olfactory Receptor 52L2 3
  • OR52L2P 5

External Ids for OR52L2P Gene

Previous HGNC Symbols for OR52L2P Gene

  • OR52L2

Previous GeneCards Identifiers for OR52L2P Gene

  • GC11U900570
  • GC11M006035
  • GC11M006078

Summaries for OR52L2P Gene

Entrez Gene Summary for OR52L2P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR52L2P Gene

OR52L2P (Olfactory Receptor Family 52 Subfamily L Member 2 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot Summary for OR52L2P Gene

Additional gene information for OR52L2P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR52L2P Gene

Genomics for OR52L2P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR52L2P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J006069 Enhancer 0.2 Ensembl 5.3 -11.2 -11234 1.5 OR52X1P piR-32559-059 piR-30444-046 piR-37567-026 OR56A1 OR52L2P OR56B4 lnc-OR56A3-1
GH11J006061 Enhancer 0.3 Ensembl 0.7 -4.7 -4671 0.8 SMC3 RAD21 OR56A1 OR52B2 OR52L2P OR52X1P OR56B4 lnc-OR56A3-1
GH11J006054 Enhancer 0.2 Ensembl 0.7 +3.6 3629 0.2 OR56A1 OR56A4 OR52W1 C11orf42 FHIP1B OR52B2 CAVIN3 OR52L2P OR56A7P OR56B4
GH11J006052 Enhancer 0.2 Ensembl 0.4 +5.8 5829 0.2 OR56A4 OR52W1 C11orf42 FHIP1B OR52B2 CAVIN3 OR52L2P OR56A7P OR56A1 OR56B4
GH11J006048 Enhancer 0.2 Ensembl 0.4 +10.0 10029 0.2 OR56A7P OR56A4 OR52L2P OR56A1 OR56B4 lnc-OR56A3-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR52L2P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OR52L2P Gene

Latest Assembly
chr11:6,057,219-6,058,330
(GRCh38/hg38)
Size:
1,112 bases
Orientation:
Minus strand

Previous Assembly
chr11:6,078,449-6,079,560
(GRCh37/hg19 by Entrez Gene)
Size:
1,112 bases
Orientation:
Minus strand

chr11:6,078,546-6,079,505
(GRCh37/hg19 by Ensembl)
Size:
960 bases
Orientation:
Minus strand

Genomic View for OR52L2P Gene

Genes around OR52L2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR52L2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR52L2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR52L2P Gene

Proteins for OR52L2P Gene

  • Protein details for OR52L2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGH6-O52L2_HUMAN
    Recommended name:
    Putative olfactory receptor 52L2
    Protein Accession:
    Q8NGH6
    Secondary Accessions:
    • Q6IFK8

    Protein attributes for OR52L2P Gene

    Size:
    319 amino acids
    Molecular mass:
    35227 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR52L2P Gene

Post-translational modifications for OR52L2P Gene

  • Glycosylation at Asn20

Other Protein References for OR52L2P Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR52L2P Gene

Domains & Families for OR52L2P Gene

Gene Families for OR52L2P Gene

Protein Domains for OR52L2P Gene

Suggested Antigen Peptide Sequences for OR52L2P Gene

GenScript: Design optimal peptide antigens:
  • Olfactory receptor OR11-74 (O52L2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGH6

UniProtKB/Swiss-Prot:

O52L2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR52L2P: view

Function for OR52L2P Gene

Molecular function for OR52L2P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR52L2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR52L2P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR52L2P Gene

Localization for OR52L2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR52L2P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR52L2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR52L2P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR52L2P Gene

Pathways & Interactions for OR52L2P Gene

PathCards logo

SuperPathways for OR52L2P Gene

genes like me logo Genes that share pathways with OR52L2P: view

Pathways by source for OR52L2P Gene

Gene Ontology (GO) - Biological Process for OR52L2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR52L2P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR52L2P Gene

Drugs & Compounds for OR52L2P Gene

No Compound Related Data Available

Transcripts for OR52L2P Gene

mRNA/cDNA for OR52L2P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR52L2P Gene

No ASD Table

Relevant External Links for OR52L2P Gene

GeneLoc Exon Structure for
OR52L2P

Expression for OR52L2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR52L2P Gene

mRNA differential expression in normal tissues according to GTEx for OR52L2P Gene

This gene is overexpressed in Testis (x23.0) and Whole Blood (x22.4).
genes like me logo Genes that share expression patterns with OR52L2P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR52L2P Gene

Orthologs for OR52L2P Gene

Evolution for OR52L2P Gene

ENSEMBL:
Gene Tree for OR52L2P (if available)
TreeFam:
Gene Tree for OR52L2P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR52L2P

No data available for Orthologs for OR52L2P Gene

Paralogs for OR52L2P Gene

(443) SIMAP similar genes for OR52L2P Gene using alignment to 1 proteins:

  • O52L2_HUMAN
genes like me logo Genes that share paralogs with OR52L2P: view

No data available for Paralogs for OR52L2P Gene

Variants for OR52L2P Gene

Additional Variant Information for OR52L2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR52L2P
Leiden Open Variation Database (LOVD)
OR52L2P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR52L2P Gene

Disorders for OR52L2P Gene

No disorders were found for OR52L2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR52L2P Gene

Publications for OR52L2P Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR52L2P Gene

Sources for OR52L2P Gene