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Aliases for OR52E5 Gene

Aliases for OR52E5 Gene

  • Olfactory Receptor Family 52 Subfamily E Member 5 2 3 5
  • Olfactory Receptor, Family 52, Subfamily E, Member 5 2
  • Olfactory Receptor OR11-56 Pseudogene 3
  • Olfactory Receptor 52E5 3
  • OR11-56 3

External Ids for OR52E5 Gene

Previous GeneCards Identifiers for OR52E5 Gene

  • GC11U990500
  • GC11P005887
  • GC11P005878
  • GC11P005922

Summaries for OR52E5 Gene

Entrez Gene Summary for OR52E5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR52E5 Gene

OR52E5 (Olfactory Receptor Family 52 Subfamily E Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR52E4.

UniProtKB/Swiss-Prot for OR52E5 Gene

  • Odorant receptor.

Gene Wiki entry for OR52E5 Gene

Additional gene information for OR52E5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR52E5 Gene

Genomics for OR52E5 Gene

Genomic Locations for OR52E5 Gene

Genomic Locations for OR52E5 Gene
9,523 bases
Plus strand

Genomic View for OR52E5 Gene

Genes around OR52E5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR52E5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR52E5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR52E5 Gene

No data available for GeneHancer (GH) Regulatory Elements for OR52E5 Gene

Proteins for OR52E5 Gene

  • Protein details for OR52E5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 52E5
    Protein Accession:

    Protein attributes for OR52E5 Gene

    327 amino acids
    Molecular mass:
    36851 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05782.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for OR52E5 Gene

Post-translational modifications for OR52E5 Gene

Other Protein References for OR52E5 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR52E5 Gene

Domains & Families for OR52E5 Gene

Gene Families for OR52E5 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR52E5 Gene

Suggested Antigen Peptide Sequences for OR52E5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR52E5: view

Function for OR52E5 Gene

Molecular function for OR52E5 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR52E5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR52E5: view
genes like me logo Genes that share phenotypes with OR52E5: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR52E5 Gene

Localization for OR52E5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR52E5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR52E5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA,TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR52E5: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR52E5 Gene

Pathways & Interactions for OR52E5 Gene

genes like me logo Genes that share pathways with OR52E5: view

Pathways by source for OR52E5 Gene

Interacting Proteins for OR52E5 Gene

Gene Ontology (GO) - Biological Process for OR52E5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IBA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR52E5: view

No data available for SIGNOR curated interactions for OR52E5 Gene

Drugs & Compounds for OR52E5 Gene

No Compound Related Data Available

Transcripts for OR52E5 Gene

mRNA/cDNA for OR52E5 Gene

(1) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR52E5 Gene

No ASD Table

Relevant External Links for OR52E5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR52E5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR52E5 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR52E5 Gene:

genes like me logo Genes that share expression patterns with OR52E5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR52E5 Gene

Orthologs for OR52E5 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR52E5 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Or52e5 51 Olfr678
  • chr7:105,069,469-105,070,407
Species where no ortholog for OR52E5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR52E5 Gene

Gene Tree for OR52E5 (if available)
Gene Tree for OR52E5 (if available)
Evolutionary constrained regions (ECRs) for OR52E5: view image

Paralogs for OR52E5 Gene

Paralogs for OR52E5 Gene

(438) SIMAP similar genes for OR52E5 Gene using alignment to 1 proteins:

  • O52E5_HUMAN
genes like me logo Genes that share paralogs with OR52E5: view

Variants for OR52E5 Gene

Sequence variations from dbSNP and Humsavar for OR52E5 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs16926732 -- p.Asp209Gly
rs17234326 -- p.Ile165Thr
rs7106300 -- p.Pro234Leu

Additional Variant Information for OR52E5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR52E5 Gene

Disorders for OR52E5 Gene

No disorders were found for OR52E5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR52E5 Gene

Publications for OR52E5 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR52E5 Gene

Sources for OR52E5 Gene

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