Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR51H1 Gene

Aliases for OR51H1 Gene

  • Olfactory Receptor Family 51 Subfamily H Member 1 2 3 5
  • Olfactory Receptor 51H1 3 3 4
  • Olfactory Receptor, Family 51, Subfamily H, Member 1 Pseudogene 2 3
  • Olfactory Receptor OR11-25 3 4
  • OR51H1P 3 4
  • Olfactory Receptor, Family 51, Subfamily H, Member 1 2
  • Seven Transmembrane Helix Receptor 3

External Ids for OR51H1 Gene

Previous HGNC Symbols for OR51H1 Gene

  • OR51H1P

Previous GeneCards Identifiers for OR51H1 Gene

  • GC11U990348

Summaries for OR51H1 Gene

Entrez Gene Summary for OR51H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51H1 Gene

OR51H1 (Olfactory Receptor Family 51 Subfamily H Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR51H1 Gene

Additional gene information for OR51H1 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51H1 Gene

Genomics for OR51H1 Gene

GeneHancer (GH) Regulatory Elements for OR51H1 Gene

Promoters and enhancers for OR51H1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J004862 Enhancer 0.6 Ensembl ENCODE 600.7 +0.6 551 2.6 SP1 NANOG OR51H1 OR51A6P OR51S1 MMP26
GH11J004892 Enhancer 0.6 ENCODE 10.5 -28.6 -28584 0 ZNF24 NFE2 FOS ARNT FOSL1 NFIC JUND SMARCE1 OR51A6P OR51G1 OR51H1 OR51A7 MMP26
GH11J004865 Enhancer 0.3 Ensembl 0.7 -2.1 -2149 0.4 POLR2A OR51F2 OR51A7 OR51F1 OR51A6P OR51H1 OR51H2P MMP26
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR51H1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for OR51H1 Gene

Genomic Locations for OR51H1 Gene
4,043 bases
Minus strand
946 bases
Minus strand

Genomic View for OR51H1 Gene

Genes around OR51H1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51H1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51H1 Gene

Proteins for OR51H1 Gene

  • Protein details for OR51H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51H1
    Protein Accession:
    Secondary Accessions:
    • Q6IFI3

    Protein attributes for OR51H1 Gene

    302 amino acids
    Molecular mass:
    33766 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51H1 Gene

Post-translational modifications for OR51H1 Gene

No Post-translational modifications

Other Protein References for OR51H1 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for OR51H1 Gene

Domains & Families for OR51H1 Gene

Gene Families for OR51H1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR51H1 Gene

Suggested Antigen Peptide Sequences for OR51H1 Gene

GenScript: Design optimal peptide antigens:
  • Olfactory receptor OR11-25 (O51H1_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51H1: view

Function for OR51H1 Gene

Molecular function for OR51H1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR51H1 Gene

Gene Ontology (GO) - Molecular Function for OR51H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA 21873635
genes like me logo Genes that share ontologies with OR51H1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51H1 Gene

Localization for OR51H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR51H1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51H1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR51H1 Gene

Pathways & Interactions for OR51H1 Gene

genes like me logo Genes that share pathways with OR51H1: view

Pathways by source for OR51H1 Gene

Interacting Proteins for OR51H1 Gene

Gene Ontology (GO) - Biological Process for OR51H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51H1: view

No data available for SIGNOR curated interactions for OR51H1 Gene

Drugs & Compounds for OR51H1 Gene

No Compound Related Data Available

Transcripts for OR51H1 Gene

mRNA/cDNA for OR51H1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR51H1 Gene

No ASD Table

Relevant External Links for OR51H1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51H1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR51H1 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR51H1 Gene

Orthologs for OR51H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51H1 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Or51h1 51 Olfr555 35
  • 79 (a)
Olfr573-ps1 35
  • 76 (a)
Or51h5 51 Olfr572
  • chr7:102,927,630-102,928,583
Or51h7 51 Olfr573
  • chr7:102,941,685-102,942,575
(Canis familiaris)
Mammalia OR51H1P 35
  • 77 (a)
(Bos Taurus)
Mammalia -- 35
  • 76 (a)
-- 35
  • 74 (a)
(Monodelphis domestica)
Mammalia OR51H1P 35
  • 71 (a)
Species where no ortholog for OR51H1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51H1 Gene

Gene Tree for OR51H1 (if available)
Gene Tree for OR51H1 (if available)
Evolutionary constrained regions (ECRs) for OR51H1: view image

Paralogs for OR51H1 Gene Pseudogenes for OR51H1 Gene

genes like me logo Genes that share paralogs with OR51H1: view

No data available for Paralogs for OR51H1 Gene

Variants for OR51H1 Gene

Sequence variations from dbSNP and Humsavar for OR51H1 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000772882 -- 4,859,536(-) A/G 3_prime_UTR_variant
rs1001834242 -- 4,859,226(-) T/A/C downstream_transcript_variant
rs1002967047 -- 4,861,306(-) A/G upstream_transcript_variant
rs1003559991 -- 4,860,062(-) A/G coding_sequence_variant, missense_variant
rs1004125573 -- 4,861,917(-) C/T upstream_transcript_variant

Variation tolerance for OR51H1 Gene

Gene Damage Index Score: 6.71; 78.69% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR51H1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR51H1 Gene

Disorders for OR51H1 Gene

Additional Disease Information for OR51H1

No disorders were found for OR51H1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51H1 Gene

Publications for OR51H1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 58

Products for OR51H1 Gene

Sources for OR51H1 Gene

Loading form....