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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...
Aliases for OR51B2 Gene
Aliases for OR51B2 Gene
- Olfactory Receptor Family 51 Subfamily B Member 2 2 3
- Olfactory Receptor Family 51 Subfamily B Member 2 (Gene/Pseudogene) 2 5
- Odorant Receptor HOR5'Beta3 3 4
- Olfactory Receptor 51B2 3 4
- Olfactory Receptor 51B1 3 4
- OR51B1P 3 4
- Olfactory Receptor, Family 51, Subfamily B, Member 2 (Gene/Pseudogene) 2
- HOR5'Beta3 3
- OR51B2 5
External Ids for OR51B2 Gene
- HGNC: 14703
- Entrez Gene: 79345
- Ensembl: ENSG00000279012
- UniProtKB: Q9Y5P1
- HORDE: OR51B2
Previous HGNC Symbols for OR51B2 Gene
- OR51B1P
Previous GeneCards Identifiers for OR51B2 Gene
- GC11M006092
- GC11M005646
- GC11M005303
- GC11M005308
- GC11M005301
- GC11M005344
- GC11M005327
- GC11M005337
Summaries for OR51B2 Gene
-
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
GeneCards Summary for OR51B2 Gene
OR51B2 (Olfactory Receptor Family 51 Subfamily B Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51B6.
UniProtKB/Swiss-Prot Summary for OR51B2 Gene
-
Odorant receptor.
Additional gene information for OR51B2 Gene
- HGNC(14703)
- Entrez Gene(79345)
- Ensembl(ENSG00000279012)
- UniProtKB(Q9Y5P1)
- Open Targets Platform(ENSG00000279012)
- Search for OR51B2 at DataMed
- Search for OR51B2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR51B2 Gene
Genomics for OR51B2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OR51B2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH11J005623 | Promoter/Enhancer | 2 | EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas | 1.9 | -301.1 | -301084 | 3.2 | SP1 REST POLR2A STAT3 RELA PKNOX1 SMAD5 RCOR1 HDAC1 CEBPB | TRIM34 lnc-OR52H1-1 TRIM5 TRIM22 OR51B2 OR56B4 OR56A1 OR56A3 OR52N4 OR51Q1 | |
| GH11J005546 | Enhancer | 0.2 | FANTOM5 | 5.2 | -221.9 | -221894 | 0.1 | OR56A1 OR56A3 OR51Q1 OR52E8 OR52N1 OR56A4 OR52N4 OR52E2 OR52E4 OR52A1 | ||
| GH11J005328 | Enhancer | 0.2 | FANTOM5 | 3.3 | -4.8 | -4826 | 0.4 | piR-48209-076 OR51G1 OR51T1 OR52N2 OR52N4 OR52D1 OR52J3 MMP26 OR51L1 OR51B2 | ||
| GH11J005379 | Enhancer | 0.2 | FANTOM5 | 2.1 | -55.6 | -55640 | 0 | piR-48209-078 OR51V1 OR51T1 HBB OR51B5 OR51G1 OR56B1 OR52J3 OR51L1 OR52N4 | ||
| GH11J005342 | Enhancer | 0.7 | Ensembl ENCODE | 0.4 | -19.3 | -19344 | 1.9 | RELA IKZF2 DPF2 JUN FOS EP300 IKZF1 MTA2 | OR51B5 OR51B6 OR51B8P OR51B2 lnc-HBE1-1 HBE1 HBG2 ENSG00000239920 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OR51B2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OR51B2
- Top Transcription factor binding sites by QIAGEN in the OR51B2 gene promoter:
-
- AML1a
- Brachyury
- c-Myc
- Evi-1
- HNF-3beta
- LCR-F1
- Max1
- POU3F2
Genomic Locations for OR51B2 Gene
Genomic Locations for OR51B2 Gene
- chr11:5,323,298-5,324,352
- (GRCh38/hg38)
- Size:
- 1,055 bases
- Orientation:
- Minus strand
- chr11:5,344,528-5,345,582
- (GRCh37/hg19)
- Size:
- 1,055 bases
- Orientation:
- Minus strand
Genomic View for OR51B2 Gene
Genes around OR51B2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p15.4 by HGNC
- 11p15.4 by Entrez Gene
- 11p15.4 by Ensembl
OR51B2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR51B2 Gene
Proteins for OR51B2 Gene
-
Protein details for OR51B2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y5P1-O51B2_HUMAN
- Recommended name:
- Olfactory receptor 51B2
- Protein Accession:
- Q9Y5P1
- Q17R53
- Q96RD4
Protein attributes for OR51B2 Gene
- Size:
- 312 amino acids
- Molecular mass:
- 35373 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for OR51B2 Gene
Other Protein References for OR51B2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
- HORDE protein sequence:
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR51B2
- Origene Custom Protein Services for OR51B2
No data available for DME Specific Peptides for OR51B2 Gene
Domains & Families for OR51B2 Gene
Gene Families for OR51B2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for OR51B2 Gene
- InterPro:
- Blocks:
-
- Olfactory receptor signature
- ProtoNet:
Suggested Antigen Peptide Sequences for OR51B2 Gene
- GenScript: Design optimal peptide antigens:
-
- Olfactory receptor 51B1 (O51B2_HUMAN)
- Olfactory receptor, family 51, subfamily B, member 2 (Q17R53_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y5P1- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR51B2 Gene
Molecular function for OR51B2 Gene
- UniProtKB/Swiss-Prot Function:
- Odorant receptor.
Phenotypes From GWAS Catalog for OR51B2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | IBA | 21873635 |
Phenotypes for OR51B2 Gene
- GenomeRNAi human phenotypes for OR51B2:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Decreased epidermal growth factor (EGF) endocytosis, decreased transferrin (TF) endocytosis
- Increased gamma-H2AX phosphorylation
- shRNA abundance <= 25%
- Decreased viability in esophageal squamous lineage
- Decreased circadian period length
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR51B2 - Select products 50% OFF >
- * OR51B2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR51B2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR51B2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR51B2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR51B2
- Browse OriGene Inhibitory RNA Products For OR51B2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR51B2
Clone Products
- Applied Biological Materials (abm): Clones for OR51B2 - Select products 50% OFF >
- * OR51B2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR51B2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR51B2
Cell Line Products
-
Horizon Cell Lines for OR51B2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51B2 Gene
Localization for OR51B2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR51B2 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR51B2 Gene
Pathways & Interactions for OR51B2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory transduction | ||
Pathways by source for OR51B2 Gene
4 Reactome pathways for OR51B2 Gene
1 KEGG pathway for OR51B2 Gene
Interacting Proteins for OR51B2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | IEA | -- |
| GO:0007608 | sensory perception of smell | IEA | -- |
| GO:0050896 | response to stimulus | IEA | -- |
| GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
No data available for SIGNOR curated interactions for OR51B2 Gene
Transcripts for OR51B2 Gene
mRNA/cDNA for OR51B2 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000624187 939 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR51B2 - Select products 50% OFF >
- * OR51B2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR51B2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR51B2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR51B2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR51B2
- Browse OriGene Inhibitory RNA Products For OR51B2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR51B2
Clone Products
- Applied Biological Materials (abm): Clones for OR51B2 - Select products 50% OFF >
- * OR51B2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR51B2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR51B2
Relevant External Links for OR51B2 Gene
- GeneLoc Exon Structure for
- OR51B2
Expression for OR51B2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR51B2
SOURCE GeneReport for Unigene cluster for OR51B2 Gene:
Hs.680163Evidence on tissue expression from TISSUES for OR51B2 Gene
- Nervous system(4)
Primer Products
-
OriGene qPCR primer pairs for OR51B2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR51B2 Gene
Orthologs for OR51B2 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC745965 30 |
|
||
| Dog (Canis familiaris) |
Mammalia | LOC485258 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Or51b17 46 Olfr64 30 17 |
|
|
|
| Rat (Rattus norvegicus) |
Mammalia | Olr131 30 |
|
- Species where no ortholog for OR51B2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Cow (Bos Taurus)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for OR51B2 Gene
- ENSEMBL:
- Gene Tree for OR51B2 (if available)
- TreeFam:
- Gene Tree for OR51B2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for OR51B2: view image
Paralogs for OR51B2 Gene
Paralogs for OR51B2 Gene
- OR51B6 5
- OR51B5 5
- OR51B4 5
- OR51V1 5
- OR51G1 5
- OR51G2 5
- OR51F2 5
- OR51Q1 5
- OR51C1P 5
- OR51A4 5
- OR51M1 5
- OR51A2 5
- OR51L1 5
- OR52B4 5
- OR51A7 5
- OR51I2 5
- OR51E1 5
- OR51T1 5
- OR52E2 5
- OR52E5 5
- OR52D1 5
- OR52E8 5
- OR51D1 5
- OR52R1 5
- OR52A1 5
- OR52E4 5
- OR51I1 5
- OR52B6 5
- OR52H1 5
- OR52N2 5
- OR52B2 5
- OR52K2 5
- OR52K1 5
- OR52A5 5
- OR52N4 5
- OR52E6 5
- OR52N1 5
- OR52L1 5
- OR52M1 5
- OR51E2 5
- OR52N5 5
- OR51S1 5
- OR52W1 5
- OR52I2 5
- OR52J3 5
- OR52I1 5
- OR52E1 5
- OR56B1 5
- OR56B4 5
(417) SIMAP similar genes for OR51B2 Gene using alignment to 2 proteins:
- O51B2_HUMAN
- Q17R53_HUMAN
- OR51B6
- OR51B5
- OR51B4
- OR51V1
- OR51G1
- OR51F1
- OR51L1
- OR51I2
- OR51G2
- OR51F2
- OR51M1
- OR51I1
- OR51H1P
- OR51E2
- OR51A4
- OR52K3P
- OR51E1
- OR51A2
- OR51Q1
- OR51A1P
- OR51T1
- OR52K2
- OR51A7
- OR52E8
- OR52K1
- OR52M1
- OR51D1
- OR52R1
- OR52E6
- OR52D1
- OR52A5
- OR52J3
- OR52Z1
- OR52N5
- OR52H1
- OR52E4
- OR52E1
- OR52E2
- OR52L1
- OR52P1P
- OR52N2
- OR52N1
- OR52L2P
- OR52N4
- OR52B6
- OR52A1
- OR52B2
- OR52E5
- OR52I2
- OR52B1P
- OR51S1
- OR52B4
- OR56B2P
- OR52W1
- OR52I1
- OR56A5
- OR56A4
- OR51J1
- OR56B3P
- OR56B1
- OR56A3
- OR56A1
- OR52A4
- OR5M3
- OR6Q1
- OR6K3
- OR6F1
- OR5B2
- OR56B4
- OR2AT4
- OR13D1
- OR10J5
- OR10J4
- OR8H3
- OR6V1
- OR6N1
- OR17-130
- OR8J2
- OR7G1
- OR6N2
- OR5F1
- OR5B3
- OR8U9
- OR5AU1
- OR10J3
- OR10J1
- OR2K2
- OR1S2
- OR1S1
- OR1J1
- OR13C8
- OR9A4
- OR2A12
- OR16-90
- OR16-88
- OR10R3P
- OR10J6P
- OR8H2
- OR5T2
- OR5AN1
- OR5A2
- OR8A1
- OR2D3
- OR10A2
- OR4X2
- OR2T4
- OR2M4
- OR2F1
- OR2A2
- OR2A14
- OR1N2
- OR1F12
- OR1F1
- OR1C1
- OR16-37
- OR16-36
- OR14J1
- OR10H3
- OR10G9
- OR10G4
- OR10AD1
- OR9Q1
- OR8G1
- OR8D1
- OR5M11
- OR5M10
- OR9A1P
- OR2A25
- OR4B1
- OR1L8
- OR16-89
- OR14A2
- OR13C5
- OR10AG1
- OR5AR1
- hA2aR
- OR9Q2
- OR9A2
- OR8U1
- OR8I2
- OR8H1
- OR8G5
- OR8D2
- OR8B12
- OR6X1
- OR6P1
- OR6A2
- OR5T3
- OR5B17
- OR5AS1
- OR5AL1
- OR9G9
- OR6K6
- OR1A1
- OR4X1
- OR4D2
- OR2T29
- OR2T12
- OR2S2
- OR2M3
- OR2J4P
- OR2F2
- OR1M1
- OR1K1
- OR1J4
- OR1A2
- OR13H1
- OR13C9
- OR13C3
- OR13C2
- OR10X1
- OR10T2
- OR10P1
- OR10H5
- OR10G8
- OR10G7
- OR5E1P
- OR9I1
- OR9G1
- OR8G2
- OR8D4
- OR7G2
- OR7A2P
- OR6B2
- OR5M9
- OR5M8
- OR5L1
- OR5G3
- OR5D3
- OR5AK3P
- OR5AK2
- OR2A7
- OR1D2
- OR4S1
- OR4M1
- OR2AG1
- OR2A5
- OR1G1
- OR13G1
- OR11L1
- OR11H4
- OR10Q1
- OR10H1
- OR10A5
- OR8K1
- OR8B3
- OR8B2
- OR7G3
- OR7A5
- OR6T1
- OR6S1
- OR6C4
- OR6B1
- OR5V1
- OR5T1
- OR5M1
- OR5L2
- OR5J2
- OR5I1
- OR5D13
- OR5B21
- OR5B12
- OR5AC1
- OR9K2
- OR8U8
- OR4S2
- OR2T8
- OR2M2
- OR2AK2
- OR1I1
- OR1B1
- OR11G2
- OR4K1
- OR4D10
- OR4D1
- OR2T5
- OR2T33
- OR2T11
- OR2T10
- OR2AP1
- OR2A4
- OR1J2
- OR1E1
- OR13C4
- OR11H1
- OR10V1
- OR10R2
- OR10H4
- OR10A7
- OR7-139
- OR6M1
- OR5A1
- OR5H15
- OR2B11
- OR4N5
- OR4F5
- OR4F4
- OR4F17
- OR4C15
- OR2V2
- OR2B6
- OR1L4
- OR1L3
- OR1F2P
- OR12D3
- OR10H2
- OR2A1
- OR4A47
- PJCG2
- PJCG1
- OR8K5
- OR8B8
- OR7E85P
- OR7D2
- OR7C2
- OR7-140
- OR6Y1
- OR6K2
- OR6C74
- OR6C6
- OR6B3
- OR5P3
- OR5P2
- OR5D18
- OR5D14
- OR7E24
- OR6C75
- OR6C70
- OR6C65
- OR6C1
- OR4A5
- OR2V1
- OR2M5
- OR2C1
- OR1L1
- OR11H12
- OR10A4
- OR4Q3
- OR4N4
- OR4N2
- OR4L1
- OR4K5
- OR4K2
- OR4K17
- OR4K14
- OR4K13
- OR4F6
- OR4D6
- OR4D11
- OR4C46
- OR4C3
- OR2Z1
- OR2L2
- OR2J1
- OR2D2
- OR2C3
- OR2A42
- OR1Q1
- OR1P1
- OR1N1
- OR1L6
- OR1E2
- OR1D4
- OR17-137
- OR14C36
- OR14A16
- OR13F1
- OR12D2
- OR11H7
- OR11H6
- OR11H2
- OR11A1
- OR10K2
- OR10K1
- OR10C1
- OR10A6
- OR10A3
- OR8K3
- OR8B4
- OR7C1
- OR5H6
- OR5H1
- OR4M2
- OR4F15
- OR2B3
- OR2AG2
- OR17-16
- OR10G6
- HSA12
- OR5H14
- OR5AP2
- OR7A17
- OR6J1
- OR5K2
- OR5H2
- OR5D16
- OR6C3
- OR4C13
- OR2T6
- OR2T1
- OR4Q2
- OR4P4
- OR4K3
- OR4F3
- OR4F29
- OR4F21
- OR4F16
- OR4E1
- OR4D9
- OR2M7
- OR2L5
- OR2J3
- OR2J2
- OR2B8P
- OR1D5
- OR14L1P
- OR13J1
- OR10Z1
- OR10W1
- OLFR 42A
- 6M1-16
- OR14I1
- OR5R1
- OR5K4
- OR5K1
- OR3A3
- OR2H2
- OR4E2
- OR4D5
- OR4C6
- OR4C12
- OR2T35
- OR2T34
- OR2T2
- OR11H13P
- OR7D4
- OR2L8
- OR9G4
- OR7A10
- OR5K3
- OR6C76
- OR5AC2
- OR4K15
- OR3A1
- OR2T7
- OR4A4P
- OR2W3
- OR2T3
- OR2T27
- OR2L3
- OR2H5P
- OR2H1
- OR2G2
- OR1E3
- OR10D3
- JCG4
- HSA10
Variants for OR51B2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OR51B2 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 730590 | Benign: not provided | 5,323,848(-) | A/G | SYNONYMOUS_VARIANT | |
| 776565 | Benign: not provided | 5,324,294(-) | A/C | MISSENSE_VARIANT | |
| rs10837814 | - | p.Leu134Phe | |||
| rs11036814 | - | p.Ser312Arg | |||
| rs11036815 | - | p.Pro283Ser |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1046068 | CNV | gain | 25217958 |
| nsv1048608 | CNV | gain | 25217958 |
| nsv524400 | CNV | loss | 19592680 |
| nsv819271 | CNV | gain | 19587683 |
Residual Variation Intolerance Score:
48.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
14.32;
96.30% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OR51B2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- OR51B2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51B2 Gene
Disorders for OR51B2 Gene
Additional Disease Information for OR51B2
No disorders were found for OR51B2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51B2 Gene
Publications for OR51B2 Gene
- DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4
- Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. (PMID: 10220430) Bulger M … von Doorninck JH (Proceedings of the National Academy of Sciences of the United States of America 1999) 3 4
- Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T … Lancet D (BMC genomics 2012) 3
- Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
- A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I … Lancet D (BMC bioinformatics 2006) 3
ExternalLinks
Products for OR51B2 Gene
- Custom Antibody Services
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- Browse OriGene Inhibitory RNA Products For OR51B2
- OriGene qPCR primer pairs for OR51B2
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- OriGene ORF clones in human for OR51B2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Sino Biological Human cDNA Clone for OR51B2
- Browse Sino Biological Recombinant Proteins
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- High-throughput Antibody Production Service
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Invitrogen Antibodies for OR51B2 (AFLGC-OR51B2)
- VectorBuilder Custom and pre-made DNA vectors for OR51B2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OR51B2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OR51B2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OR51B2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OR51B2
- antibodies-online: Show 5 available OR51B2 Antibodies ranked by validation data
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- antibodies-online: Search results for available OR51B2 related products ranked by validation data
- antibodies-online: Search results for available OR51B2 related products ranked by validation data
- Horizon Cell Lines for OR51B2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR51B2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR51B2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OR51B2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR51B2
- Boster Bio Antibodies for OR51B2
- Browse Boster Bio ELISA Kits
Sources for OR51B2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
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- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
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- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
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- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
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- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
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- (83) Illumina
- (84) COMPARTMENTS
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- (89) antibodies-online
- (90) CYP
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- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
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- (104) diseasecard
- (105) NIH Rare Diseases
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- (136) Human Protein Atlas
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- (143) Applied Biosystems
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- (148) RNACentral
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- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
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- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
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- (177) snoDB
- (178) MirGeneDB