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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...
Aliases for OR4X1 Gene
Aliases for OR4X1 Gene
- Olfactory Receptor Family 4 Subfamily X Member 1 2 3
- Olfactory Receptor Family 4 Subfamily X Member 1 (Gene/Pseudogene) 2 5
- Olfactory Receptor OR11-104 3 4
- Olfactory Receptor 4X1 3 4
- Olfactory Receptor, Family 4, Subfamily X, Member 1 (Gene/Pseudogene) 2
- Olfactory Receptor, Family 4, Subfamily X, Member 1 2
- OR11-104 3
- OR4X1 5
External Ids for OR4X1 Gene
- HGNC: 14854
- Entrez Gene: 390113
- Ensembl: ENSG00000176567
- UniProtKB: Q8NH49
- HORDE: OR4X1
Previous GeneCards Identifiers for OR4X1 Gene
- GC11U990332
- GC11P048250
- GC11P048241
Summaries for OR4X1 Gene
-
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]
GeneCards Summary for OR4X1 Gene
OR4X1 (Olfactory Receptor Family 4 Subfamily X Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR4X2.
UniProtKB/Swiss-Prot Summary for OR4X1 Gene
-
Odorant receptor.
Additional gene information for OR4X1 Gene
- HGNC(14854)
- Entrez Gene(390113)
- Ensembl(ENSG00000176567)
- UniProtKB(Q8NH49)
- Open Targets Platform(ENSG00000176567)
- Search for OR4X1 at DataMed
- Search for OR4X1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR4X1 Gene
Genomics for OR4X1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OR4X1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OR4X1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OR4X1
- Top Transcription factor binding sites by QIAGEN in the OR4X1 gene promoter:
-
- AML1a
- NF-kappaB
- NF-kappaB1
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- Nkx3-1 v3
- Nkx3-1 v4
- Pax-4a
Genomic Locations for OR4X1 Gene
Genomic Locations for OR4X1 Gene
- chr11:48,263,861-48,264,778
- (GRCh38/hg38)
- Size:
- 918 bases
- Orientation:
- Plus strand
- chr11:48,285,413-48,286,330
- (GRCh37/hg19)
- Size:
- 918 bases
- Orientation:
- Plus strand
Genomic View for OR4X1 Gene
Genes around OR4X1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p11.2 by HGNC
- 11p11.2 by Entrez Gene
- 11p11.2 by Ensembl
OR4X1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR4X1 Gene
Proteins for OR4X1 Gene
-
Protein details for OR4X1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NH49-OR4X1_HUMAN
- Recommended name:
- Olfactory receptor 4X1
- Protein Accession:
- Q8NH49
- Q6IF74
Protein attributes for OR4X1 Gene
- Size:
- 305 amino acids
- Molecular mass:
- 34222 Da
- Quaternary structure:
- No Data Available
Protein Expression for OR4X1 Gene
Post-translational modifications for OR4X1 Gene
-
Glycosylation at Asn6 and Asn18
- NX_Q8NH49 (NX_Q8NH49-1)
Other Protein References for OR4X1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
- HORDE protein sequence:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for OR4X1
- Invitrogen Antibodies for OR4X1 (AFLGC-OR4X1)
-
Biorbyt antibodies for OR4X1
-
Boster Bio Antibodies for OR4X1
Protein Products
-
OriGene Purified Proteins for OR4X1
- Search Origene for MassSpec and Protein Over-expression Lysates for OR4X1
- Origene Custom Protein Services for OR4X1
Assay Products
No data available for DME Specific Peptides for OR4X1 Gene
Domains & Families for OR4X1 Gene
Gene Families for OR4X1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for OR4X1 Gene
- InterPro:
- Blocks:
-
- Olfactory receptor signature
- ProtoNet:
Suggested Antigen Peptide Sequences for OR4X1 Gene
- GenScript: Design optimal peptide antigens:
-
- Olfactory receptor OR11-104 (OR4X1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8NH49- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR4X1 Gene
Molecular function for OR4X1 Gene
- UniProtKB/Swiss-Prot Function:
- Odorant receptor.
Phenotypes From GWAS Catalog for OR4X1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004888 | transmembrane signaling receptor activity | IBA | -- |
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | IEA | -- |
Phenotypes for OR4X1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR4X1 - Select products 50% OFF >
- * OR4X1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR4X1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR4X1
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR4X1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR4X1
- Browse OriGene Inhibitory RNA Products For OR4X1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR4X1
Clone Products
- Applied Biological Materials (abm): Clones for OR4X1 - Select products 50% OFF >
- * OR4X1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR4X1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR4X1
Cell Line Products
-
Horizon Cell Lines for OR4X1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR4X1 Gene
Localization for OR4X1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR4X1 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR4X1 Gene
Pathways & Interactions for OR4X1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory transduction | ||
Pathways by source for OR4X1 Gene
4 Reactome pathways for OR4X1 Gene
1 KEGG pathway for OR4X1 Gene
Interacting Proteins for OR4X1 Gene
GPS-Prot Interaction Network for OR4X1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | IBA | -- |
| GO:0007608 | sensory perception of smell | IEA | -- |
| GO:0050896 | response to stimulus | IEA | -- |
| GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
No data available for SIGNOR curated interactions for OR4X1 Gene
Transcripts for OR4X1 Gene
mRNA/cDNA for OR4X1 Gene
- 1 REFSEQ mRNAs :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000320048 918 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR4X1 - Select products 50% OFF >
- * OR4X1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR4X1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR4X1
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR4X1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR4X1
- Browse OriGene Inhibitory RNA Products For OR4X1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR4X1
Clone Products
- Applied Biological Materials (abm): Clones for OR4X1 - Select products 50% OFF >
- * OR4X1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR4X1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR4X1
Relevant External Links for OR4X1 Gene
- GeneLoc Exon Structure for
- OR4X1
Expression for OR4X1 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OR4X1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR4X1
SOURCE GeneReport for Unigene cluster for OR4X1 Gene:
Hs.553742Primer Products
-
OriGene qPCR primer pairs for OR4X1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR4X1 Gene
Orthologs for OR4X1 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Cow (Bos Taurus) |
Mammalia | OR4X1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | LOC483609 30 |
|
||
| OR4X1 31 |
|
OneToOne | |||
| Rat (Rattus norvegicus) |
Mammalia | Olr735 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Olfr1270 31 |
|
ManyToMany | |
| Or4x5-ps 46 Olfr1268-ps1 |
|
|
|||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany |
- Species where no ortholog for OR4X1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Paralogs for OR4X1 Gene
Paralogs for OR4X1 Gene
- OR4X2 5
- OR4B1 5
- OR4S1 5
- OR4S2 5
- OR4C46 5
- OR4C15 5
- OR4C6 5
- OR4C3 5
- OR4C13 5
- OR4C11 5
- OR4C5 5
- OR4A47 5
- OR4C12 5
- OR4C45 5
- OR4A5 5
- OR4A15 5
- OR4Q2 5
- OR4E1 5
- OR4Q3 5
- OR4P4 5
- OR4E2 5
- OR4D10 5
- OR4D9 5
- OR4A8 5
- OR4D5 5
- OR4A16 5
- OR4K1 5
- OR4M1 5
- OR4C16 5
- OR4D6 5
- OR4D11 5
- OR4K17 5
- OR4D1 5
- OR4F4 5
- OR4F17 5
- ENSG00000182974 5
- OR4M2 5
- OR4K15 5
- OR4L1 5
- OR4F5 5
- OR4D2 5
- ENSG00000275249 5
- OR4K5 5
- OR4F6 5
- OR4F15 5
- ENSG00000279408 5
- LINC02203 5
- ENSG00000285472 5
- OR4N4 5
- OR4F21 5
- OR4N2 5
- OR4K2 5
- OR4K14 5
- OR4K13 5
- OR4N5 5
- OR1F1 5
- OR4F29 5
- OR4F16 5
- OR6N1 5
- OR4F3 5
- OR7A10 5
- LOC102723532 5
- OR1K1 5
- OR10Z1 5
- OR7D2 5
- OR1G1 5
- OR7A5 5
- OR7C1 5
- OR10J1 5
- OR12D2 5
- OR12D3 5
- OR1L1 5
- OR1L3 5
- OR1L4 5
- OR1L6 5
- OR10T2 5
- OR10R2 5
- OR7E24 5
- OR1E1 5
- OR1E2 5
- OR1S1 5
- OR7C2 5
- OR2A5 5
- OR2A1 5
- OR2A42 5
- OR1J2 5
- OR1L8 5
- OR10K1 5
- OR6N2 5
- OR1P1 5
- OR1S2 5
- OR7A17 5
- OR1C1 5
- OR13G1 5
- OR2A12 5
- OR5BS1P 5
- OR10J5 5
- OR1J4 5
- OR1N1 5
- OR1Q1 5
- OR1J1 5
- OR6K3 5
- OR6K6 5
- OR1M1 5
- OR7D4 5
- OR2A25 5
- OR2A2 5
- OR2A14 5
- OR1N2 5
- OR10K2 5
- OR7G2 5
- OR7G3 5
- OR1A1 5
- OR2A7 5
- OR2AT4 5
- OR6K2 5
- OR7G1 5
- OR1D5 5
- OR1D2 5
- OR2A4 5
- OR8S1 5
- OR4K3 5
- OR1B1 5
- OR1I1 5
- OR10J3 5
- OR1A2 5
- OR3A1 5
- OR3A2 5
- OR3A3 5
- OR12D1 5
- OR10J4 5
- OR1R1P 5
(444) SIMAP similar genes for OR4X1 Gene using alignment to 1 proteins:
- OR4X1_HUMAN
- OR4C15
- OR4C46
- OR4C13
- OR4B1
- OR4X2
- OR4C3
- OR4C11
- OR4A15
- OR4S2
- OR4Q3
- OR4C6
- OR4A5
- OR4A47
- OR4S1
- OR4C5
- OR4C12
- OR4A4P
- OR4Q2
- OR4P4
- OR4C16
- OR4A8P
- OR4A16
- OR4E2
- OR4K3
- OR4D9
- OR4D11
- OR4D2
- OR4N5
- OR4N4
- OR4K2
- OR4K17
- OR4F17
- OR4E1
- OR4D10
- OR4D1
- OR4N2
- OR4K5
- OR4K13
- OR4F5
- OR4F4
- OR4C45
- OR4M1
- OR4L1
- OR4K1
- OR4D5
- OR8J3
- OR4M2
- OR4K15
- OR4F21
- OR4D6
- OR4F3
- OR4F29
- OR4F16
- OR8B12
- OR8U1
- OR8J1
- OR5G3
- OR4F6
- OR10G9
- OR10G6
- OR10G2
- OR4K14
- OR10G4
- OR8B8
- OR8B3
- OR5V1
- OR5J2
- OR5AR1
- OR8U9
- OR8U8
- OR8K1
- OR8D1
- OR8B2
- OR8A1
- OR5AP2
- OR4F15
- OR2K2
- OR1L6
- OR1L3
- OR1L1
- OR1F1
- OR10S1
- OR10G7
- OR10G3
- OR1L8
- OR10A3
- OR5R1
- OR5P3
- OR5L2
- OR5F1
- OR8J2
- OR8D2
- OR5B21
- OR5AU1
- OR5AS1
- OR2D3
- OR2A5
- OR2A12
- OR1L4
- OR1K1
- OR1F2P
- OR1F12
- OR1C1
- OR13C3
- OR10G8
- OR10A5
- OR10A4
- OR13G1
- OR13C4
- OR12D3
- OR10C1
- OR10A7
- OR5H14
- OR8G2
- OR9Q2
- OR8H1
- OR8G5
- OR7C1
- OR5M1
- OR9K2
- OR8H2
- OR7E24
- OR6C70
- OR5T2
- OR5T1
- OR5M11
- OR5H6
- OR5E1P
- OR5D13
- OR5B12
- OR2T1
- OR2F1
- OR1S2
- OR1J1
- OR1D2
- OR16-89
- OR13A1
- OR11L1
- OR11H7
- OR10J4
- OR10A2
- JCG4
- OR2A2
- OR1J4
- OR1G1
- OR13C9
- OR10R3P
- OR10K1
- OR10J5
- OR10H3
- OR8G1
- OR6C74
- OR2A14
- OR8K5
- OR8H3
- OR7A5
- OR7A17
- OR7A10
- OR9G4
- OR8K3
- OR8D4
- OR8B4
- OR7G3
- OR7D2
- OR7A2P
- OR6N1
- OR6C1
- OR5T3
- OR5P2
- OR5M8
- OR5M10
- OR5K2
- OR5K1
- OR5H2
- OR5D18
- OR5B2
- OR5AC1
- OR3A3
- OR3A1
- OR2J4P
- OR2J1
- OR2G6
- OR2C3
- OR2B11
- OR2AK2
- OR1S1
- OR1D4
- OR1A1
- OR16-90
- OR16-37
- OR16-36
- OR11H4
- OR10W1
- OR10R2
- OR10P1
- OR10K2
- OR10D4P
- OR2W1
- OR2S2
- OR2J3
- OR2G3
- OR2B6
- OR2B3
- OR1M1
- OR1J2
- OR13C2
- OR12D2
- OR10H1
- OR10A6
- OR1D5
- OR10Q1
- OR9Q1
- OR9A4
- OR7D4
- OR6X1
- OR6A2
- OR5I1
- PJCG1
- OR7C2
- OR6Y1
- OR6K3
- OR5L1
- OR5K4
- OR5H15
- OR5H1
- OR5B17
- OR5AK3P
- OR5AK2
- OR5AC2
- OR5A2
- OR5A1
- OR3A2
- OR2W5
- OR2W3
- OR2V2
- OR2V1
- OR2C1
- OR2AG2
- OR2A25
- OR1P1
- OR16-88
- OR14A2
- OR13F1
- OR13D1
- OR13C5
- OR10H5
- OR10AG1
- OLFR 42A
- OR2F2
- OR2D2
- OR2AE1
- OR1Q1
- OR10T2
- OR10H4
- OR10D3
- OR2A1
- OR11A1
- OR9I1
- OR8S1
- OR5W2
- OR8I2
- OR7G2
- OR7G1
- OR6P1
- OR6N2
- OR6M1
- OR6C75
- OR6C68
- OR6C65
- OR6C6
- OR6C4
- OR6C3
- OR6C2
- OR5M3
- OR5K3
- OR5D3
- OR5D16
- OR5C1
- OR5B3
- OR5AN1
- OR2Y1
- OR2W6P
- OR2T7
- OR2T33
- OR2T27
- OR2L13
- OR2AP1
- OR2AJ1
- OR2A42
- OR1N2
- OR17-130
- OR14L1P
- OR14C36
- OR10Z1
- OR10X1
- OR10J1
- OR10AD1
- 6M1-16
- OR2Z1
- OR2J2
- OR2B2
- OR1N1
- OR1I1
- OR13C8
- OR10J6P
- OR10H2
- OR7E5P
- OR6V1
- OR6B1
- OR52D1
- olfr89
- OR9G9
- OR9G1
- OR7-139
- OR6Q1
- OR6K6
- OR6K2
- OR6J1
- OR6B3
- OR6B2
- OR52E8
- OR3A4P
- OR2T8
- OR2T5
- OR2T4
- OR2T35
- OR2T29
- OR2T12
- OR2T11
- OR2L2
- OR2H5P
- OR2G2
- OR2B8P
- OR2AT4
- OR2A7
- OR1E1
- OR17-16
- OR17-15
- OR17-137
- OR14I1
- OR13H1
- OR11H6
- OR11H2
- OR11H12
- OR11H1
- OR10J3
- OLFR 42B
- OR2H1
- OR2AG1
- OR1A2
- OR14J1
- OR2L8
- OR6T1
- OR5M9
- OR7E85P
- OR7-140
- OR6S1
- OR5D14
- OR52E4
- OR2T2
- OR2T10
- OR2M3
- OR2H2
- OR14A16
- OR11H13P
- OR11G2
- OR10V1
- OR2L3
- OR2A4
- OR1E2
- OR9A2
- OR9A1P
- OR6F1
- OR6C76
- OR5AL1
- OR52E2
- OR52B2
- OR2T6
- OR2T34
- OR2T3
- OR2M5
- OR2M2
- OR2L5
- OR1E3
- OR14K1
- OR13J1
- OR1E3P
- FKSG35
- OR51M1
- OR51V1
- OR52Z1
- OR52M1
- OR52I2
- OR52B6
- OR51F2
- OR2M7
- OR2M4
- OR2I1P
- OR1B1
- OR52I1
- OR52E1
- OR51H1P
- OR51E1
- OR7E35P
- OR56B1
- OR56A3
- OR52K1
- OR52J3
- OR52E6
- OR52B1P
- OR56B4
- OR56B2P
- OR56A5
- OR56A4
- OR52N5
- OR52N2
- OR52N1
- OR52K2
- OR51G1
- OR51B6
- OR51B2
- OR10AC1P
- OR56A1
- OR52H1
- OR52E5
- OR52B4
- OR51T1
- OR51G2
- OR51F1
- OR51E2
- OR51B5
- OR51B4
- OR51I2
- OR51I1
- OR52R1
- OR52N4
- OR52L2P
- OR52L1
- OR51L1
- OR51D1
- OR51A4
- OR52P1P
- OR51S1
- OR51Q1
Variants for OR4X1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OR4X1 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs10838852 | - | p.Pro282Ser | |||
| rs12798361 | - | p.Leu196Gln | |||
| rs1503193 | - | p.Arg144Gly | |||
| rs16905753 | - | p.Pro165Leu | |||
| rs17199104 | - | p.Asp246Asn |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1111n100 | CNV | gain | 25217958 |
| dgv1112n100 | CNV | gain | 25217958 |
| dgv198e214 | CNV | gain | 21293372 |
| esv3891986 | CNV | gain | 25118596 |
| nsv1041394 | CNV | gain | 25217958 |
| nsv428253 | CNV | loss | 18775914 |
| nsv467871 | CNV | gain | 19166990 |
| nsv467873 | CNV | loss | 19166990 |
| nsv469953 | CNV | loss | 18288195 |
| nsv508628 | CNV | deletion | 20534489 |
| nsv554211 | CNV | gain | 21841781 |
| nsv554212 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
77.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
16.75;
97.89% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OR4X1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4X1 Gene
Disorders for OR4X1 Gene
Additional Disease Information for OR4X1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for OR4X1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR4X1 Gene
Publications for OR4X1 Gene
- A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population. (PMID: 17964544) Takabatake N … Kubota I (Biochemical and biophysical research communications 2007) 3 41
- The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
- Association study of the three functional polymorphisms (TAS2R46G>A, OR4C16G>A, and OR4X1A>T) with recurrent pregnancy loss. (PMID: 30203366) Ryu CS … Kim NK (Genes & genomics 2019) 3
- The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors. (PMID: 26549023) Zhou L … Hanemann CO (Oncogene 2016) 3
- Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T … Lancet D (BMC genomics 2012) 3
ExternalLinks
Products for OR4X1 Gene
- Custom Antibody ServicesOriGene Antibodies for OR4X1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for OR4X1
- Search Origene for MassSpec and Protein Over-expression Lysates for OR4X1
- Origene Custom Protein Services for OR4X1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR4X1
- Browse OriGene Inhibitory RNA Products For OR4X1
- OriGene qPCR primer pairs for OR4X1
- OriGene CRISPR knockouts for OR4X1
- OriGene ORF clones in human for OR4X1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For OR4X1
- Sino Biological Human cDNA Clone for OR4X1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals proteins and lysates for OR4X1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for OR4X1 (AFLGC-OR4X1)
- VectorBuilder Custom and pre-made DNA vectors for OR4X1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OR4X1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OR4X1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OR4X1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OR4X1
- antibodies-online: Show 12 available OR4X1 Antibodies ranked by validation data
- Compare Top OR4X1 Antibodies
- antibodies-online: Show 10 available OR4X1 Elisa Kits ranked by validation data
- Compare Top OR4X1 Elisa Kits
- antibodies-online: Search results for available OR4X1 related products ranked by validation data
- Horizon Cell Lines for OR4X1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR4X1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR4X1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OR4X1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR4X1
- Boster Bio Antibodies for OR4X1
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for OR4X1
Sources for OR4X1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB