Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR4A4P Gene

Aliases for OR4A4P Gene

  • Olfactory Receptor Family 4 Subfamily A Member 4 Pseudogene 2 3 5
  • Olfactory Receptor, Family 4, Subfamily A, Member 4 Pseudogene 2
  • Putative Olfactory Receptor 4A4 4
  • Olfactory Receptor OR11-107 4
  • OR4A4P 5
  • OR4A4 3

External Ids for OR4A4P Gene

Previous HGNC Symbols for OR4A4P Gene

  • OR4A4

Previous GeneCards Identifiers for OR4A4P Gene

  • GC11M051466
  • GC11M051315

Summaries for OR4A4P Gene

Entrez Gene Summary for OR4A4P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4A4P Gene

OR4A4P (Olfactory Receptor Family 4 Subfamily A Member 4 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot Summary for OR4A4P Gene

Additional gene information for OR4A4P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR4A4P Gene

Genomics for OR4A4P Gene

Genomic Locations for OR4A4P Gene

Latest Assembly
chr11:54,659,667-54,660,596
(GRCh38/hg38)
Size:
930 bases
Orientation:
Plus strand

Previous Assembly
chr11:51,458,684-51,459,613
(GRCh37/hg19 by Entrez Gene)
Size:
930 bases
Orientation:
Minus strand

chr11:51,458,685-51,459,614
(GRCh37/hg19 by Ensembl)
Size:
930 bases
Orientation:
Minus strand

Genomic View for OR4A4P Gene

Genes around OR4A4P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR4A4P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR4A4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4A4P Gene

No data available for GeneHancer (GH) Regulatory Elements for OR4A4P Gene

Proteins for OR4A4P Gene

  • Protein details for OR4A4P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGN8-OR4A4_HUMAN
    Recommended name:
    Putative olfactory receptor 4A4
    Protein Accession:
    Q8NGN8
    Secondary Accessions:
    • Q6IF83
    • Q96R66

    Protein attributes for OR4A4P Gene

    Size:
    299 amino acids
    Molecular mass:
    33593 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4A4P Gene

Post-translational modifications for OR4A4P Gene

  • Glycosylation at Asn6 and Asn87

Other Protein References for OR4A4P Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR4A4P Gene

Domains & Families for OR4A4P Gene

Gene Families for OR4A4P Gene

Protein Domains for OR4A4P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR4A4P Gene

GenScript: Design optimal peptide antigens:
  • Olfactory receptor OR11-107 (OR4A4_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGN8

UniProtKB/Swiss-Prot:

OR4A4_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4A4P: view

Function for OR4A4P Gene

Molecular function for OR4A4P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR4A4P Gene

Gene Ontology (GO) - Molecular Function for OR4A4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4A4P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR4A4P Gene

Localization for OR4A4P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4A4P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR4A4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR4A4P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR4A4P Gene

Pathways & Interactions for OR4A4P Gene

PathCards logo

SuperPathways for OR4A4P Gene

genes like me logo Genes that share pathways with OR4A4P: view

Pathways by source for OR4A4P Gene

Interacting Proteins for OR4A4P Gene

Gene Ontology (GO) - Biological Process for OR4A4P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR4A4P: view

No data available for SIGNOR curated interactions for OR4A4P Gene

Drugs & Compounds for OR4A4P Gene

No Compound Related Data Available

Transcripts for OR4A4P Gene

mRNA/cDNA for OR4A4P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR4A4P Gene

No ASD Table

Relevant External Links for OR4A4P Gene

GeneLoc Exon Structure for
OR4A4P

Expression for OR4A4P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR4A4P Gene

genes like me logo Genes that share expression patterns with OR4A4P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR4A4P Gene

Orthologs for OR4A4P Gene

Evolution for OR4A4P Gene

ENSEMBL:
Gene Tree for OR4A4P (if available)
TreeFam:
Gene Tree for OR4A4P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR4A4P

No data available for Orthologs for OR4A4P Gene

Paralogs for OR4A4P Gene

(444) SIMAP similar genes for OR4A4P Gene using alignment to 1 proteins:

  • OR4A4_HUMAN
genes like me logo Genes that share paralogs with OR4A4P: view

No data available for Paralogs for OR4A4P Gene

Variants for OR4A4P Gene

Additional Variant Information for OR4A4P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR4A4P
Leiden Open Variation Database (LOVD)
OR4A4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR4A4P Gene

Disorders for OR4A4P Gene

No disorders were found for OR4A4P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR4A4P Gene

Publications for OR4A4P Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR4A4P Gene

Sources for OR4A4P Gene