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Aliases for OR4A47 Gene

Aliases for OR4A47 Gene

  • Olfactory Receptor Family 4 Subfamily A Member 47 2 3 5
  • Olfactory Receptor OR11-113 3 4
  • Olfactory Receptor, Family 4, Subfamily A, Member 47 2
  • Olfactory Receptor 4A47 3
  • OR11-113 3

External Ids for OR4A47 Gene

Previous GeneCards Identifiers for OR4A47 Gene

  • GC11U900133

Summaries for OR4A47 Gene

Entrez Gene Summary for OR4A47 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR4A47 Gene

OR4A47 (Olfactory Receptor Family 4 Subfamily A Member 47) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR4A5.

UniProtKB/Swiss-Prot for OR4A47 Gene

  • Odorant receptor.

Gene Wiki entry for OR4A47 Gene

Additional gene information for OR4A47 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR4A47 Gene

Genomics for OR4A47 Gene

GeneHancer (GH) Regulatory Elements for OR4A47 Gene

Top Transcription factor binding sites by QIAGEN in the OR4A47 gene promoter:
  • GATA-1
  • Sox5
  • RSRFC4
  • Nkx2-2
  • AREB6
  • CUTL1
  • ITF-2
  • Tal-1beta
  • SREBP-1a
  • SREBP-1b

Genomic Locations for OR4A47 Gene

Genomic Locations for OR4A47 Gene
6,315 bases
Plus strand
1,064 bases
Plus strand

Genomic View for OR4A47 Gene

Genes around OR4A47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR4A47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR4A47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR4A47 Gene

Proteins for OR4A47 Gene

  • Protein details for OR4A47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 4A47
    Protein Accession:

    Protein attributes for OR4A47 Gene

    309 amino acids
    Molecular mass:
    34760 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR4A47 Gene

Post-translational modifications for OR4A47 Gene

  • Glycosylation at Asn87 and Asn6
  • Modification sites at PhosphoSitePlus

Other Protein References for OR4A47 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR4A47 Gene

Domains & Families for OR4A47 Gene

Gene Families for OR4A47 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR4A47 Gene

Suggested Antigen Peptide Sequences for OR4A47 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR4A47: view

Function for OR4A47 Gene

Molecular function for OR4A47 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR4A47 Gene

Gene Ontology (GO) - Molecular Function for OR4A47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR4A47: view
genes like me logo Genes that share phenotypes with OR4A47: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR4A47 Gene

Localization for OR4A47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR4A47 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR4A47 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR4A47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR4A47: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR4A47 Gene

Pathways & Interactions for OR4A47 Gene

genes like me logo Genes that share pathways with OR4A47: view

Pathways by source for OR4A47 Gene

Interacting Proteins for OR4A47 Gene

Gene Ontology (GO) - Biological Process for OR4A47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
genes like me logo Genes that share ontologies with OR4A47: view

No data available for SIGNOR curated interactions for OR4A47 Gene

Drugs & Compounds for OR4A47 Gene

No Compound Related Data Available

Transcripts for OR4A47 Gene

mRNA/cDNA for OR4A47 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR4A47 Gene

Olfactory receptor, family 4, subfamily A, member 47:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR4A47 Gene

No ASD Table

Relevant External Links for OR4A47 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR4A47 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR4A47 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR4A47 Gene:


SOURCE GeneReport for Unigene cluster for OR4A47 Gene:

genes like me logo Genes that share expression patterns with OR4A47: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR4A47 Gene

Orthologs for OR4A47 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR4A47 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC745857 33
  • 98.92 (n)
OR4A47 34
  • 98 (a)
(Canis familiaris)
Mammalia LOC100683879 33
  • 87.01 (n)
OR4A47 34
  • 85 (a)
(Bos Taurus)
Mammalia LOC785969 33
  • 84.31 (n)
-- 34
  • 79 (a)
-- 34
  • 78 (a)
-- 34
  • 77 (a)
-- 34
  • 76 (a)
-- 34
  • 75 (a)
-- 34
  • 74 (a)
(Rattus norvegicus)
Mammalia Olr720 33
  • 83.22 (n)
(Mus musculus)
Mammalia Or4a47 51 Olfr1256 16 34 33
  • 83.01 (n)
(Monodelphis domestica)
Mammalia OR4A47 34
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 64 (a)
Species where no ortholog for OR4A47 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR4A47 Gene

Gene Tree for OR4A47 (if available)
Gene Tree for OR4A47 (if available)
Evolutionary constrained regions (ECRs) for OR4A47: view image

Paralogs for OR4A47 Gene

Paralogs for OR4A47 Gene

(455) SIMAP similar genes for OR4A47 Gene using alignment to 2 proteins:

  • O4A47_HUMAN
  • B9EIM4_HUMAN Pseudogenes for OR4A47 Gene

genes like me logo Genes that share paralogs with OR4A47: view

Variants for OR4A47 Gene

Sequence variations from dbSNP and Humsavar for OR4A47 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000154452 -- 48,487,672(+) T/A upstream_transcript_variant
rs1000834987 -- 48,486,816(+) C/A upstream_transcript_variant
rs1002420171 -- 48,490,142(+) G/T downstream_transcript_variant
rs1002966712 -- 48,489,081(+) G/A coding_sequence_variant, missense_variant
rs1005631811 -- 48,488,282(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR4A47 Gene

Variant ID Type Subtype PubMed ID
dgv1111n100 CNV gain 25217958
dgv1112n100 CNV gain 25217958
dgv1113n100 CNV loss 25217958
dgv1114n100 CNV loss 25217958
dgv1780n54 CNV loss 21841781
dgv48e55 CNV loss 17911159
esv2759824 CNV gain+loss 17122850
esv2760610 CNV gain 21179565
esv3579513 CNV loss 25503493
esv3626235 CNV loss 21293372
esv3626241 CNV loss 21293372
esv3626242 CNV gain 21293372
esv3891986 CNV gain 25118596
nsv428253 CNV loss 18775914
nsv467871 CNV gain 19166990
nsv467874 CNV gain 19166990
nsv469953 CNV loss 18288195
nsv469954 CNV gain 18288195
nsv554211 CNV gain 21841781
nsv554220 CNV loss 21841781
nsv554222 CNV loss 21841781
nsv554223 CNV gain 21841781
nsv832144 CNV loss 17160897
nsv975841 CNV duplication 23825009

Variation tolerance for OR4A47 Gene

Residual Variation Intolerance Score: 79.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.90; 67.66% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR4A47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR4A47 Gene

Disorders for OR4A47 Gene

Additional Disease Information for OR4A47

No disorders were found for OR4A47 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR4A47 Gene

Publications for OR4A47 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4 58
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  3. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. (PMID: 24144296) Cheng CY … Baird PN (American journal of human genetics 2013) 3 58
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for OR4A47 Gene

Sources for OR4A47 Gene

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