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Aliases for OR2W5 Gene

Aliases for OR2W5 Gene

  • Olfactory Receptor Family 2 Subfamily W Member 5 (Gene/Pseudogene) 2 3 5
  • OR2W5P 3 4
  • Olfactory Receptor, Family 2, Subfamily W, Member 5 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 2, Subfamily W, Member 5 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily W, Member 5 2
  • Putative Olfactory Receptor 2W5 3
  • Olfactory Receptor 2W5 3
  • OST722 3

External Ids for OR2W5 Gene

Previous HGNC Symbols for OR2W5 Gene

  • OR2W5P

Previous GeneCards Identifiers for OR2W5 Gene

  • GC01P244595
  • GC01P243960
  • GC01P245721
  • GC01P247654

Summaries for OR2W5 Gene

Entrez Gene Summary for OR2W5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene has a coding sequence that is comparable in length to other olfactory receptor genes, but it should be noted that a frameshift is present in the 3' coding region that disrupts the 7-transmembrane domain structure in the protein. It is unclear if the protein can function as an olfactory receptor or if an alternate function is served. For this reason, this gene has also been interpreted to be a pseudogene. [provided by RefSeq, Jan 2010]

GeneCards Summary for OR2W5 Gene

OR2W5 (Olfactory Receptor Family 2 Subfamily W Member 5 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR2W5 Gene

  • Odorant receptor.

Additional gene information for OR2W5 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2W5 Gene

Genomics for OR2W5 Gene

GeneHancer (GH) Regulatory Elements for OR2W5 Gene

Promoters and enhancers for OR2W5 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I247494 Enhancer 0.6 ENCODE 0.4 +6.9 6901 0.1 FOSL1 LCORL NFIC SMAD1 NFIB IKZF1 CEBPB NFE2 SPI1 OR2B11 OR2C3 OR2G3 ZNF496 OR2W5 GCSAML
GH01I247475 Enhancer 0.5 ENCODE 0.4 -11.4 -11445 1.5 AFF1 NR2F1 IKZF1 SPI1 GCSAML-AS1 OR2W5 OR2B11
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around OR2W5 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR2W5 gene promoter:

Genomic Locations for OR2W5 Gene

Genomic Locations for OR2W5 Gene
4,323 bases
Plus strand

Genomic View for OR2W5 Gene

Genes around OR2W5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2W5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2W5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR2W5 Gene

Proteins for OR2W5 Gene

  • Protein details for OR2W5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative olfactory receptor 2W5
    Protein Accession:
    Secondary Accessions:
    • B9EH85

    Protein attributes for OR2W5 Gene

    320 amino acids
    Molecular mass:
    35528 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2W5 Gene

Post-translational modifications for OR2W5 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR2W5 Gene

REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2W5 Gene

Domains & Families for OR2W5 Gene

Gene Families for OR2W5 Gene

Protein Domains for OR2W5 Gene

Suggested Antigen Peptide Sequences for OR2W5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2W5: view

Function for OR2W5 Gene

Molecular function for OR2W5 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR2W5 Gene

Gene Ontology (GO) - Molecular Function for OR2W5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR2W5: view

Phenotypes for OR2W5 Gene

genes like me logo Genes that share phenotypes with OR2W5: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR2W5 Gene

Localization for OR2W5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2W5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR2W5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2W5: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR2W5 Gene

Pathways & Interactions for OR2W5 Gene

genes like me logo Genes that share pathways with OR2W5: view

Pathways by source for OR2W5 Gene

Interacting Proteins for OR2W5 Gene

Gene Ontology (GO) - Biological Process for OR2W5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway TAS --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2W5: view

No data available for SIGNOR curated interactions for OR2W5 Gene

Drugs & Compounds for OR2W5 Gene

No Compound Related Data Available

Transcripts for OR2W5 Gene

mRNA/cDNA for OR2W5 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR2W5 Gene

Olfactory receptor, family 2, subfamily W, member 5:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR2W5 Gene

No ASD Table

Relevant External Links for OR2W5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2W5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR2W5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OR2W5 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR2W5 Gene:


SOURCE GeneReport for Unigene cluster for OR2W5 Gene:

genes like me logo Genes that share expression patterns with OR2W5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR2W5 Gene

Orthologs for OR2W5 Gene

Evolution for OR2W5 Gene

Gene Tree for OR2W5 (if available)
Gene Tree for OR2W5 (if available)

No data available for Orthologs for OR2W5 Gene

Paralogs for OR2W5 Gene

(368) SIMAP similar genes for OR2W5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2W5: view

No data available for Paralogs for OR2W5 Gene

Variants for OR2W5 Gene

Sequence variations from dbSNP and Humsavar for OR2W5 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002504693 -- 247,489,982(+) T/C upstream_transcript_variant
rs1002529506 -- 247,492,472(+) A/G downstream_transcript_variant
rs1002557170 -- 247,489,713(+) G/A upstream_transcript_variant
rs1002609694 -- 247,489,509(+) G/T upstream_transcript_variant
rs1002610691 -- 247,492,743(+) A/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR2W5 Gene

Variant ID Type Subtype PubMed ID
dgv115n67 CNV loss 20364138
esv2675635 CNV deletion 23128226
esv2727818 CNV deletion 23290073
esv33129 CNV gain+loss 17666407
esv3589517 CNV loss 21293372
nsv1011097 CNV gain 25217958
nsv827764 CNV loss 20364138

Additional Variant Information for OR2W5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OR2W5 Gene

Disorders for OR2W5 Gene

Additional Disease Information for OR2W5

No disorders were found for OR2W5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2W5 Gene

Publications for OR2W5 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 2 3 58
  4. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C … Soranzo N (Nature 2011) 44 58
  5. Germline genomic variants associated with childhood acute lymphoblastic leukemia. (PMID: 19684603) Treviño LR … Relling MV (Nature genetics 2009) 44 58

Products for OR2W5 Gene

Sources for OR2W5 Gene

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