Aliases for OR2J3 Gene
Aliases for OR2J3 Gene
External Ids for OR2J3 Gene
Previous GeneCards Identifiers for OR2J3 Gene
- GC06U990203
- GC06P029188
- GC06P029079
- GC06P028887
Summaries for OR2J3 Gene
-
This gene encodes a G-protein-coupled receptor (GPCR) that functions as an olfactory receptor. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The protein encoded by this gene responds to cis-3-hexen-1-ol, which is released by wounded plants, including cut grass. This gene is situated in a cluster of similar olfactory-receptor coding genes on chromosome 6. [provided by RefSeq, May 2013]
GeneCards Summary for OR2J3 Gene
OR2J3 (Olfactory Receptor Family 2 Subfamily J Member 3) is a Protein Coding gene. Diseases associated with OR2J3 include C3hex, Ability To Smell. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2J1.
UniProtKB/Swiss-Prot for OR2J3 Gene
-
Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as green grassy or the smell of cut grass.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2J3 Gene
Genomics for OR2J3 Gene
GeneHancer (GH) Regulatory Elements for OR2J3 Gene
Promoters and enhancers for OR2J3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06I028814 | Enhancer | 0.9 | FANTOM5 | 2.9 | -293.7 | -293681 | 0.1 | ZSCAN4 KLF17 ZNF76 ZBTB40 ZNF2 ETS1 ZNF335 ZNF213 ZNF366 KLF7 | ZNF311 ZKSCAN3 ZFP57 ZBED9 ZNF602P OR14J1 GPX6 OR2W1 OR2J3 OR2B3 | |
| GH06I029467 | Enhancer | 0.2 | FANTOM5 | 6.4 | +359.6 | 359640 | 0.3 | GC06M029436 OR10C1 ZFP57 MAS1L OR11A1 OR14J1 OR2W1 OR2J3 OR2B3 OR12D2 | ||
| GH06I028854 | Enhancer | 0.5 | FANTOM5 | 2.2 | -253.2 | -253175 | 0.2 | FOXA2 HDAC2 ZMYM3 KDM1A | HCG14 TRIM27 ENSG00000244349 HCG15 ZNF602P OR2J3 OR2B3 OR14J1 RPL13P ENSG00000225173 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around OR2J3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for OR2J3 Gene
Genomic Locations for OR2J3 Gene
- chr6:29,108,059-29,114,770
- (GRCh38/hg38)
- Size:
- 6,712 bases
- Orientation:
- Plus strand
- chr6:29,079,668-29,080,603
- (GRCh37/hg19)
Genomic View for OR2J3 Gene
Genes around OR2J3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by Ensembl
- 6p22.1 by Entrez Gene
- 6p22.1 by HGNC
OR2J3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR2J3 Gene
Proteins for OR2J3 Gene
-
Protein details for OR2J3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O76001-OR2J3_HUMAN
- Recommended name:
- Olfactory receptor 2J3
- Protein Accession:
- O76001
- B0UY52
- B9EH11
- Q5SUJ7
- Q6IF25
- Q96R15
- Q9GZK5
- Q9GZL4
- Q9GZL5
Protein attributes for OR2J3 Gene
- Size:
- 311 amino acids
- Molecular mass:
- 34950 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for OR2J3 Gene
- Glycosylation at Asn8
Other Protein References for OR2J3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
- HORDE protein sequence:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for OR2J3
- Invitrogen Antibodies for OR2J3
- Search GeneTex for Antibodies for OR2J3
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for OR2J3
- Origene Custom Protein Services for OR2J3
- Search GeneTex for Proteins for OR2J3
Assay Products
No data available for DME Specific Peptides for OR2J3 Gene
Domains & Families for OR2J3 Gene
Gene Families for OR2J3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for OR2J3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for OR2J3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O76001- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR2J3 Gene
Molecular function for OR2J3 Gene
- GENATLAS Biochemistry:
- olfactory receptor,family 2,subfamily J,member 3,G protein coupled receptor superfamily
- UniProtKB/Swiss-Prot Function:
- Odorant receptor involved in the detection of the flavor compound cis-3-hexen-1-ol (C3HEX), a compound typically described as green grassy or the smell of cut grass.
Phenotypes From GWAS Catalog for OR2J3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | IBA | -- |
Phenotypes for OR2J3 Gene
- GenomeRNAi human phenotypes for OR2J3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for OR2J3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for OR2J3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for OR2J3 gene
- Search ViGene Biosciences for OR2J3
CRISPR Products
-
OriGene CRISPR knockouts for OR2J3
- genomics-online: gRNA clones - Search results for 27 available OR2J3 gene related products
- Overview of 27 available OR2J3 gene related products
- Applied Biological Materials CRISPR for OR2J3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR2J3
- GenScript: Design CRISPR guide RNA sequences for OR2J3
miRNA for OR2J3 Gene
- miRTarBase miRNAs that target OR2J3
miRNA Products
- Search ViGene Biosciences for OR2J3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for OR2J3
- Browse OriGene Inhibitory RNA Products For OR2J3
- genomics-online: shRNA clones - Search results for 27 available OR2J3 gene related products
- Overview of 27 available OR2J3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for OR2J3 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for OR2J3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for OR2J3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for OR2J3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for OR2J3
-
ViGene Biosciences adenoviral particle packaged cDNA for OR2J3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for OR2J3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for OR2J3 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR2J3 Gene
Localization for OR2J3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR2J3 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IBA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR2J3 Gene
Pathways & Interactions for OR2J3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory Signaling Pathway | ||
| 3 | Peptide ligand-binding receptors | ||
Pathways by source for OR2J3 Gene
1 BioSystems pathway for OR2J3 Gene
4 Reactome pathways for OR2J3 Gene
1 KEGG pathway for OR2J3 Gene
Interacting Proteins for OR2J3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | -- |
| GO:0007608 | sensory perception of smell | IBA | -- |
| GO:0050896 | response to stimulus | IEA | -- |
| GO:0050911 | detection of chemical stimulus involved in sensory perception of smell | IEA | -- |
No data available for SIGNOR curated interactions for OR2J3 Gene
Transcripts for OR2J3 Gene
mRNA/cDNA for OR2J3 Gene
- (1) REFSEQ mRNAs :
- (2) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for OR2J3
- genomics-online: gRNA clones - Search results for 27 available OR2J3 gene related products
- Overview of 27 available OR2J3 gene related products
- Applied Biological Materials CRISPR for OR2J3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR2J3
- GenScript: Design CRISPR guide RNA sequences for OR2J3
miRNA Products
- Search ViGene Biosciences for OR2J3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for OR2J3
- Browse OriGene Inhibitory RNA Products For OR2J3
- genomics-online: shRNA clones - Search results for 27 available OR2J3 gene related products
- Overview of 27 available OR2J3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for OR2J3 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for OR2J3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for OR2J3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for OR2J3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for OR2J3 Gene
mRNA differential expression in normal tissues according to GTEx for OR2J3 Gene
This gene is overexpressed in Testis (x31.4).
NURSA nuclear receptor signaling pathways regulating expression of OR2J3 Gene:
OR2J3SOURCE GeneReport for Unigene cluster for OR2J3 Gene:
Hs.738947Primer Products
-
OriGene qPCR primer pairs for OR2J3
- genomics-online: primer clones - Search results for 27 available OR2J3 gene related products
- Overview of 27 available OR2J3 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR2J3 Gene
Orthologs for OR2J3 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC471931 33 |
|
||
| OR2J3 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| OR2J3 33 |
|
||||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Olfr1381 34 |
|
ManyToMany | |
| Or2j3 51 Olfr137 |
|
|
- Species where no ortholog for OR2J3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for OR2J3 Gene
Paralogs for OR2J3 Gene
(445) SIMAP similar genes for OR2J3 Gene using alignment to 1 proteins:
- OR2J4P
- OR2J1
- OR2J2
- OR2W6P
- OLFR 42A
- OR2C3
- OR2B8P
- OR2B2
- OR2G6
- 6M1-16
- OR2G3
- OR2Y1
- OR2G2
- OR2C1
- OR2H1
- OR2W1
- OR2H2
- OR2B6
- OR2B3
- OR2W3
- OR2B11
- OR2K2
- OR2H5P
- OR2A12
- olfr89
- OR4Q2
- OR2A2
- OR13C3
- OLFR 42B
- OR5B21
- OR2W5
- OR2D2
- OR2A5
- OR13F1
- OR13C9
- OR13C2
- OR10R3P
- OR10G2
- OR10A7
- OR5V1
- OR7A10
- OR5M11
- OR4Q3
- OR4E1
- OR2F1
- OR2D3
- OR2AJ1
- OR13D1
- OR2F2
- OR2A1
- OR7G3
- OR7-139
- OR5B2
- OR5AR1
- OR5AP2
- OR5A2
- OR4S2
- OR4M1
- OR2V1
- OR2T33
- OR2S2
- OR2I1P
- OR2A42
- OR2A14
- OR13C8
- OR13C5
- OR13C4
- OR10G9
- OR10G7
- OR10G4
- OR10A4
- OR12D3
- OR9Q2
- OR9Q1
- OR8G5
- OR8G1
- OR8D1
- OR8B8
- OR8B3
- OR8A1
- OR7D4
- OR7D2
- OR7A17
- OR7-140
- OR6N1
- OR5B3
- OR5B12
- OR5AS1
- OR4N5
- OR4N2
- OR4L1
- OR4K2
- OR4D5
- OR4D2
- OR4D1
- OR4C3
- OR2T8
- OR2T12
- OR2L8
- OR2L3
- OR2L2
- OR2AK2
- OR2A25
- OR1M1
- OR1J4
- OR1J1
- OR1D2
- OR13H1
- OR13G1
- OR13A1
- OR12D2
- OR10T2
- OR10R2
- OR10P1
- OR10G6
- OR10A5
- OR8G2
- OR4F3
- OR4F29
- OR4F16
- OR8J1
- OR8I2
- OR8B2
- OR8B12
- OR7G2
- OR7E86P
- OR7C2
- OR7C1
- OR7A2P
- OR6N2
- OR6C6
- OR6B3
- OR6B1
- OR5T1
- OR5M10
- OR5M1
- OR5K1
- OR5I1
- OR5G3
- OR5F1
- OR5D18
- OR5AU1
- OR5A1
- OR4N4
- OR4M2
- OR4K5
- OR4K17
- OR4K13
- OR4F6
- OR4F21
- OR4E2
- OR4C12
- OR4B1
- OR4A4P
- OR2V2
- OR2T7
- OR2T35
- OR2T27
- OR2T2
- OR2M7
- OR2M4
- OR2M2
- OR2L5
- OR2AP1
- OR2AG2
- OR2AG1
- OR2AE1
- OR2A7
- OR1G1
- OR1F1
- OR1E1
- OR11H7
- OR10Z1
- OR10Q1
- OR10J4
- OR10H2
- OR10G3
- OR10D3
- OR10AG1
- OR10A3
- OR10A2
- OR2A4
- OR11A1
- OR7A5
- OR4A47
- OR9I1
- OR9G4
- OR8U9
- OR8J2
- OR8D2
- OR6C74
- OR6B2
- OR5W2
- OR5T3
- OR5T2
- OR5M8
- OR5L2
- OR5H2
- OR5D16
- OR5C1
- OR5B17
- OR5AN1
- OR4S1
- OR4K3
- OR4K15
- OR4K1
- OR4F5
- OR4F4
- OR4F17
- OR4D10
- OR4C15
- OR4C13
- OR4A8P
- OR4A15
- OR3A3
- OR2Z1
- OR2T34
- OR2T3
- OR2T11
- OR2T1
- OR2M5
- OR1S2
- OR1S1
- OR1J2
- OR1F2P
- OR1F12
- OR1E3P
- OR1E2
- OR1D5
- OR1C1
- OR1A1
- OR17-16
- OR17-137
- OR11L1
- OR11H6
- OR11H4
- OR11G2
- OR10W1
- OR10G8
- OR10D4P
- OR10A6
- OR14J1
- OR10C1
- OR4A5
- OR8U8
- OR8U1
- OR8J3
- OR8H3
- OR8H1
- OR8B4
- OR7G1
- OR7E85P
- OR6X1
- OR6J1
- OR6F1
- OR6C70
- OR6C2
- OR6C1
- OR5M9
- OR5M3
- OR5L1
- OR5K3
- OR5K2
- OR5AL1
- OR5AK3P
- OR5AC1
- OR4P4
- OR4K14
- OR4F15
- OR4D9
- OR4D11
- OR4C46
- OR3A2
- OR2T5
- OR2T4
- OR2T29
- OR2T10
- OR2M3
- OR1N2
- OR1L8
- OR1K1
- OR1E3
- OR1D4
- OR1A2
- OR17-130
- OR16-89
- OR14A2
- OR14A16
- OR13J1
- OR10V1
- OR10S1
- OR10K1
- OR10J1
- OR10H5
- OR10H3
- OR10H1
- HSA12
- OR10J5
- OR9K2
- OR9G9
- OR9G1
- OR8K3
- OR8H2
- OR8D4
- OR7E24
- OR6Y1
- OR6S1
- OR6P1
- OR6M1
- OR6C75
- OR6C68
- OR6C65
- OR6C3
- OR6A2
- OR5R1
- OR5P2
- OR5K4
- OR5H6
- OR5AK2
- OR4X1
- OR4C11
- OR3A1
- OR2L13
- OR1Q1
- OR1P1
- OR1N1
- OR1L6
- OR1L4
- OR1L1
- OR17-15
- OR16-90
- OR16-88
- OR16-37
- OR16-36
- OR14L1P
- OR11H2
- OR11H12
- OR11H1
- OR10X1
- OR10H4
- HSA10
- OR6Q1
- OR5H14
- OR8S1
- OR7E5P
- OR6V1
- OR6T1
- OR6C76
- OR6C4
- OR5J2
- OR5H15
- OR5H1
- OR5E1P
- OR5D14
- OR5D13
- OR4X2
- OR4C6
- OR4A16
- OR2T6
- OR1L3
- OR10J3
- OR10AD1
- JCG4
- OR10K2
- OR9A4
- PJCG1
- OR8K1
- OR7E35P
- OR5P3
- OR5D3
- OR5AC2
- OR4D6
- OR4C5
- OR4C45
- OR3A4P
- OR1B1
- OR14I1
- OR14C36
- OR10AC1P
- OR8K5
- OR6K6
- OR6K3
- OR6K2
- OR4C16
- OR1I1
- OR11H13P
- OR14K1
- OR10J6P
- OR9A2
- OR52E8
- OR9A1P
- OR52L2P
- OR52E4
- OR52D1
- OR52B2
- OR52Z1
- OR52N5
- OR52K1
- OR52J3
- OR52I2
- OR52E6
- OR52I1
- OR56A5
- OR56A4
- OR56A3
- OR56A1
- OR52R1
- OR52L1
- OR52K2
- OR52H1
- OR52E1
- OR2AT4
- OR51M1
- OR56B4
- OR52P1P
- OR52N4
- OR52N2
- OR51T1
- OR51E2
- OR51E1
- OR51A2
- OR56B2P
- OR52W1
- OR52N1
- OR52M1
- OR52E5
- OR52E2
- OR52B6
- OR51L1
- OR51G2
- OR51D1
- OR51B6
- OR51B5
- OR56B1
- OR51Q1
- OR51I1
- OR51H1P
- OR51B4
- OR51B2
- OR51A4
- OR51V1
- OR51S1
- OR51I2
- OR51G1
- OR51F2
Variants for OR2J3 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for OR2J3 Gene
- OR2J3_HUMAN-O76001
- Variants Ala-113 and Gln-226 exhibit a reduced ability to smell C3HEX [MIM:615082]. When both variants are present in the same haplotype (allele 6M1-3*02), the response to C3HEX is abolished. African populations have a higher proportion of the C3HEX-nonresponsive haplotype than other populations. All haplotypes containing Gln-226 show low levels of surface expression.
| SNP ID | Clin | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs28757581 | affects, C3HEX, ability to smell | 29,112,227(+) | A/G | coding_sequence_variant, missense_variant | |
| rs3749977 | affects, C3HEX, ability to smell | 29,112,567(+) | G/A | coding_sequence_variant, missense_variant | |
| rs1000383614 | -- | 29,109,935(+) | A/G | upstream_transcript_variant | |
| rs1000811264 | -- | 29,111,622(+) | A/G | upstream_transcript_variant | |
| rs1002394973 | -- | 29,112,917(+) | C/T | downstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv10338n54 | CNV | gain | 21841781 |
| dgv1172e214 | CNV | gain | 21293372 |
| dgv1173e214 | CNV | loss | 21293372 |
| esv2763545 | CNV | loss | 21179565 |
| nsv1015796 | CNV | gain | 25217958 |
| nsv1032468 | CNV | loss | 25217958 |
| nsv1074388 | CNV | deletion | 25765185 |
| nsv1122126 | CNV | deletion | 24896259 |
| nsv1145096 | CNV | deletion | 24896259 |
| nsv428138 | CNV | gain+loss | 18775914 |
| nsv601216 | CNV | gain | 21841781 |
| nsv830623 | CNV | gain | 17160897 |
| nsv970098 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
84.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.07;
75.30% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OR2J3 Gene
SNP Genotyping and Copy Number Assay Products
Disorders for OR2J3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| c3hex, ability to smell |
|
|
Search OR2J3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for OR2J3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for OR2J3 Gene
Publications for OR2J3 Gene
- Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. (PMID: 22714804) McRae JF … Newcomb RD (Chemical senses 2012) 3 4 58
- Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PMID: 20881960) Lango Allen H … Hirschhorn JN (Nature 2010) 3 44 58
- High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos LF … Criswell LA (PLoS genetics 2009) 3 44 58
- The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
- The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
Products for OR2J3 Gene
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- genomics-online: cdna clones - Search results for 27 available OR2J3 gene related products
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Sources for OR2J3 Gene
- (1) GeneCards
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- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
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- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
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