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Aliases for OR2J1 Gene

Aliases for OR2J1 Gene

  • Olfactory Receptor Family 2 Subfamily J Member 1 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 Pseudogene 2 3
  • Olfactory Receptor 6-5 3 4
  • Hs6M1-4 3 4
  • OR2J1P 3 4
  • OR6-5 3 4
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 2, Subfamily J, Member 1 2
  • Olfactory Receptor OR6-15 3
  • Olfactory Receptor 2J1 3
  • DJ80I19.2 3
  • 6M1-4P 3
  • OR6-15 3

External Ids for OR2J1 Gene

Previous HGNC Symbols for OR2J1 Gene

  • OR2J1P

Previous GeneCards Identifiers for OR2J1 Gene

  • GC06U900570
  • GC06P029176
  • GC06P029069
  • GC06P028876
  • GC06Pi29069
  • GC06P029070

Summaries for OR2J1 Gene

Entrez Gene Summary for OR2J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

GeneCards Summary for OR2J1 Gene

OR2J1 (Olfactory Receptor Family 2 Subfamily J Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2J2.

UniProtKB/Swiss-Prot for OR2J1 Gene

  • Odorant receptor.

Gene Wiki entry for OR2J1 Gene

Additional gene information for OR2J1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR2J1 Gene

Genomics for OR2J1 Gene

Genomic Locations for OR2J1 Gene

Genomic Locations for OR2J1 Gene
3,045 bases
Plus strand
1,273 bases
Plus strand

Genomic View for OR2J1 Gene

Genes around OR2J1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2J1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2J1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for GeneHancer (GH) Regulatory Elements for OR2J1 Gene

Proteins for OR2J1 Gene

  • Protein details for OR2J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 2J1
    Protein Accession:
    Secondary Accessions:
    • A2AAS1
    • B0V1T2
    • Q9GZK1

    Protein attributes for OR2J1 Gene

    312 amino acids
    Molecular mass:
    35454 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2J1 Gene

Post-translational modifications for OR2J1 Gene

Other Protein References for OR2J1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OR2J1 Gene

Domains & Families for OR2J1 Gene

Gene Families for OR2J1 Gene

Protein Domains for OR2J1 Gene

Suggested Antigen Peptide Sequences for OR2J1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2J1: view

Function for OR2J1 Gene

Molecular function for OR2J1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR2J1 Gene

Gene Ontology (GO) - Molecular Function for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR2J1: view

Phenotypes for OR2J1 Gene

genes like me logo Genes that share phenotypes with OR2J1: view

Animal Model Products

miRNA for OR2J1 Gene

miRTarBase miRNAs that target OR2J1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR2J1 Gene

Localization for OR2J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR2J1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR2J1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR2J1 Gene

Pathways & Interactions for OR2J1 Gene

genes like me logo Genes that share pathways with OR2J1: view

Pathways by source for OR2J1 Gene

Interacting Proteins for OR2J1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000366376 for OR2J1 Gene via STRING

Gene Ontology (GO) - Biological Process for OR2J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2J1: view

No data available for SIGNOR curated interactions for OR2J1 Gene

Drugs & Compounds for OR2J1 Gene

No Compound Related Data Available

Transcripts for OR2J1 Gene

mRNA/cDNA for OR2J1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR2J1 Gene

No ASD Table

Relevant External Links for OR2J1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR2J1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR2J1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR2J1 Gene:

genes like me logo Genes that share expression patterns with OR2J1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR2J1 Gene

Orthologs for OR2J1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR2J1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OR2J1 34
  • 98 (a)
(Bos Taurus)
Mammalia -- 34
  • 87 (a)
(Mus musculus)
Mammalia Olfr137 34
  • 80 (a)
Or2au1-ps 51 Olfr762-ps1
  • chr17:38,314,181-38,314,591
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 59 (a)
Species where no ortholog for OR2J1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR2J1 Gene

Gene Tree for OR2J1 (if available)
Gene Tree for OR2J1 (if available)
Evolutionary constrained regions (ECRs) for OR2J1: view image

Paralogs for OR2J1 Gene

(452) SIMAP similar genes for OR2J1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR2J1: view

Variants for OR2J1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR2J1 Gene

A stop codon in the gene coding for this protein at position Gln-194 is responsible for functional diversity thus producing a pseudogene. The stop codon is more frequent in non-Africans than in African-Americans.

Sequence variations from dbSNP and Humsavar for OR2J1 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs3131087 -- p.Leu14Ile

Variation tolerance for OR2J1 Gene

Gene Damage Index Score: 19.95; 98.99% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR2J1 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR2J1 Gene

Disorders for OR2J1 Gene

Additional Disease Information for OR2J1

No disorders were found for OR2J1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2J1 Gene

Publications for OR2J1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 58
  2. Different noses for different people. (PMID: 12730696) Menashe I … Gilad Y (Nature genetics 2003) 4 58
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 4 58
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for OR2J1 Gene

Sources for OR2J1 Gene

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