Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR2I1P Gene

Aliases for OR2I1P Gene

  • Olfactory Receptor Family 2 Subfamily I Member 1 Pseudogene 2 3 5
  • HS6M1-14 2 3
  • OR2I3P 3 4
  • OR2I4P 3 4
  • OR2I2 3 4
  • Olfactory Receptor, Family 2, Subfamily I, Member 1 Pseudogene 2
  • Olfactory Receptor, Family 2, Subfamily I, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 4 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 5 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 7 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 8 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 9 Pseudogene 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 2 3
  • Olfactory Receptor, Family 2, Subfamily I, Member 6 3
  • Olfactory Receptor OR6-34 Pseudogene 3
  • Olfactory Receptor OR6-1 Pseudogene 3
  • Seven Transmembrane Helix Receptor 3
  • Putative Olfactory Receptor 2I1 4
  • Putative Olfactory Receptor 2I2 4
  • Putative Olfactory Receptor 2I3 4
  • Putative Olfactory Receptor 2I4 4
  • OR2I5P 3
  • OR2I7P 3
  • OR2I8P 3
  • OR2I9P 3
  • OR6-34 3
  • OR2I1P 5
  • OR2I1 3
  • OR2I6 3
  • OR6-1 3

External Ids for OR2I1P Gene

Previous HGNC Symbols for OR2I1P Gene

  • OR2I1
  • OR2I3P
  • OR2I4P
  • OR2I2

Previous GeneCards Identifiers for OR2I1P Gene

  • GC06U990205
  • GC06P029629
  • GC06P029632
  • GC06P029521
  • GC06Pm29435
  • GC06P029522
  • GC06P029603
  • GC06P029782
  • GC06P029992
  • GC06P030166
  • GC06P029719
  • GC06P030053
  • GC06P032136
  • GC06P032388
  • GC06P032291
  • GC06P033149
  • GC06P030293
  • GC06P030447
  • GC06P030624
  • GC06P030817
  • GC06P030968
  • GC06P031134
  • GC06P031302
  • GC06P031516

Summaries for OR2I1P Gene

Entrez Gene Summary for OR2I1P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR2I1P Gene

OR2I1P (Olfactory Receptor Family 2 Subfamily I Member 1 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2Y1.

UniProtKB/Swiss-Prot Summary for OR2I1P Gene

Additional gene information for OR2I1P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR2I1P Gene

Genomics for OR2I1P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR2I1P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J029552 Enhancer 0.9 FANTOM5 ENCODE 0.7 +2.3 2341 0.3 SP1 CREB1 PRDM10 RFX5 ZNF561 SP2 OSR2 ZBTB40 WT1 OVOL3 TRIM39 HCG18 TRIM26 IFITM4P UBD LINC02829 HLA-F HLA-A OR2I1P MAS1L
GH06J029553 Enhancer 0.8 ENCODE 0.7 +3.3 3302 0.2 TEAD4 KDM1A ZNF692 ZIC2 RBFOX2 PATZ1 ZNF501 EZH2 SCRT2 CTCF ZFP57 LINC01015 ENSG00000237669 OR2I1P UBD MAS1L
GH06J029558 Promoter 0.7 Ensembl 0.4 +8.7 8694 0.6 ZNF740 KAT8 POLR2A YY1 ZBTB11 EHMT2 GTF2A2 MLLT1 UBD HLA-J HLA-W ENSG00000237669 LINC02829 OR2I1P MAS1L GABBR1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR2I1P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OR2I1P Gene

Genomic Locations for OR2I1P Gene
chr6:29,550,407-29,557,721
(GRCh38/hg38)
Size:
7,315 bases
Orientation:
Plus strand
chr6:29,520,882-29,521,943
(GRCh37/hg19)
Size:
1,062 bases
Orientation:
Plus strand

Genomic View for OR2I1P Gene

Genes around OR2I1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR2I1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR2I1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR2I1P Gene

  • Protein details for OR2I1P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGU4-OR2I1_HUMAN
    Recommended name:
    Putative olfactory receptor 2I1
    Protein Accession:
    Q8NGU4

    Protein attributes for OR2I1P Gene

    Size:
    316 amino acids
    Molecular mass:
    34115 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR2I1P Gene

Post-translational modifications for OR2I1P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR2I1P Gene

ENSEMBL proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR2I1P Gene

Domains & Families for OR2I1P Gene

Gene Families for OR2I1P Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for OR2I1P Gene

InterPro:
Blocks:
  • Olfactory receptor signature
ProtoNet:

Suggested Antigen Peptide Sequences for OR2I1P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 2I4 (OR2I1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGU4

UniProtKB/Swiss-Prot:

OR2I1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR2I1P: view

Function for OR2I1P Gene

Molecular function for OR2I1P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR2I1P Gene

Gene Ontology (GO) - Molecular Function for OR2I1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR2I1P: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR2I1P Gene

Localization for OR2I1P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR2I1P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR2I1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA,TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR2I1P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR2I1P Gene

Pathways & Interactions for OR2I1P Gene

PathCards logo

SuperPathways for OR2I1P Gene

genes like me logo Genes that share pathways with OR2I1P: view

Pathways by source for OR2I1P Gene

Gene Ontology (GO) - Biological Process for OR2I1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR2I1P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR2I1P Gene

Drugs & Compounds for OR2I1P Gene

No Compound Related Data Available

Transcripts for OR2I1P Gene

mRNA/cDNA for OR2I1P Gene

3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR2I1P Gene

No ASD Table

Relevant External Links for OR2I1P Gene

GeneLoc Exon Structure for
OR2I1P

Expression for OR2I1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR2I1P Gene

mRNA differential expression in normal tissues according to GTEx for OR2I1P Gene

This gene is overexpressed in Liver (x10.9), Small Intestine - Terminal Ileum (x7.5), Pancreas (x6.3), Kidney - Cortex (x5.2), Minor Salivary Gland (x4.2), and Spleen (x4.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OR2I1P Gene



genes like me logo Genes that share expression patterns with OR2I1P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR2I1P Gene

Orthologs for OR2I1P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR2I1P Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Or2bd2 46 Olfr1344
  • chr7:6,439,902-6,440,864
Or2i1 46 Olfr94
  • chr17:37,196,809-37,197,966
Species where no ortholog for OR2I1P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR2I1P Gene

ENSEMBL:
Gene Tree for OR2I1P (if available)
TreeFam:
Gene Tree for OR2I1P (if available)

Paralogs for OR2I1P Gene

(402) SIMAP similar genes for OR2I1P Gene using alignment to 1 proteins:

  • OR2I1_HUMAN
genes like me logo Genes that share paralogs with OR2I1P: view

Variants for OR2I1P Gene

Additional Variant Information for OR2I1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR2I1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR2I1P Gene

Disorders for OR2I1P Gene

Additional Disease Information for OR2I1P

No disorders were found for OR2I1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR2I1P Gene

Publications for OR2I1P Gene

  1. Genome-wide association study in Han Chinese identifies three novel loci for human height. (PMID: 23456168) Hao Y … Gu D (Human genetics 2013) 3
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3

Products for OR2I1P Gene

Sources for OR2I1P Gene