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Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...
Aliases for OR2H2 Gene
Aliases for OR2H2 Gene
External Ids for OR2H2 Gene
Previous GeneCards Identifiers for OR2H2 Gene
- GC06U990208
- GC06P029666
- GC06P029650
- GC06P029667
- GC06P029555
- GC06P029636
- GC06P030071
- GC06P032160
- GC06P032406
- GC06P032484
- GC06P033154
- GC06P030322
- GC06P030474
- GC06P030669
- GC06P030836
- GC06P030998
- GC06P031155
- GC06P031322
- GC06P031567
Summaries for OR2H2 Gene
-
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
GeneCards Summary for OR2H2 Gene
OR2H2 (Olfactory Receptor Family 2 Subfamily H Member 2) is a Protein Coding gene. Diseases associated with OR2H2 include Acute Pulmonary Heart Disease and Acute Cor Pulmonale. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR2H1.
UniProtKB/Swiss-Prot Summary for OR2H2 Gene
-
Odorant receptor.
Additional gene information for OR2H2 Gene
- HGNC(8253)
- Entrez Gene(7932)
- Ensembl(ENSG00000204657)
- OMIM(600578)
- UniProtKB(O95918)
- Open Targets Platform(ENSG00000204657)
- Search for OR2H2 at DataMed
- Search for OR2H2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR2H2 Gene
Genomics for OR2H2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for OR2H2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around OR2H2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for OR2H2
- Top Transcription factor binding sites by QIAGEN in the OR2H2 gene promoter:
-
- E47
- Egr-3
- Hand1
- Nkx3-1
- Nkx3-1 v1
- Nkx3-1 v2
- YY1
Genomic Locations for OR2H2 Gene
Genomic Locations for OR2H2 Gene
- chr6:29,585,121-29,592,506
- (GRCh38/hg38)
- Size:
- 7,386 bases
- Orientation:
- Plus strand
- chr6:29,555,683-29,556,745
- (GRCh37/hg19)
- Size:
- 1,063 bases
- Orientation:
- Plus strand
Genomic View for OR2H2 Gene
Genes around OR2H2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.1 by HGNC
- 6p22.1 by Entrez Gene
- 6p22.1 by Ensembl
OR2H2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for OR2H2 Gene
Proteins for OR2H2 Gene
-
Protein details for OR2H2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95918-OR2H2_HUMAN
- Recommended name:
- Olfactory receptor 2H2
- Protein Accession:
- O95918
- Q15062
- Q2M1Y3
- Q5STL8
- Q5SUK1
- Q6IFN7
- Q6NTB7
- Q96R14
Protein attributes for OR2H2 Gene
- Size:
- 312 amino acids
- Molecular mass:
- 34763 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for OR2H2 Gene
Other Protein References for OR2H2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
- HORDE protein sequence:
Antibody Products
- Invitrogen Antibodies for OR2H2 (AFLGC-OR2H2)
-
Biorbyt antibodies for OR2H2
-
Boster Bio Antibodies for OR2H2
Protein Products
-
OriGene Purified Proteins for OR2H2
- Search Origene for MassSpec and Protein Over-expression Lysates for OR2H2
- Origene Custom Protein Services for OR2H2
- Novus Biologicals lysates for OR2H2
Assay Products
No data available for DME Specific Peptides for OR2H2 Gene
Domains & Families for OR2H2 Gene
Gene Families for OR2H2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- G-protein coupled receptors
- Predicted membrane proteins
Protein Domains for OR2H2 Gene
- InterPro:
- Blocks:
-
- Olfactory receptor signature
- ProtoNet:
Suggested Antigen Peptide Sequences for OR2H2 Gene
- GenScript: Design optimal peptide antigens:
-
- Olfactory receptor-like protein FAT11 (OR2H2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O95918- Family:
-
- Belongs to the G-protein coupled receptor 1 family.
Function for OR2H2 Gene
Molecular function for OR2H2 Gene
- UniProtKB/Swiss-Prot Function:
- Odorant receptor.
- GENATLAS Biochemistry:
- olfactory receptor,family 2,subfamily H,member 2,G protein coupled receptor superfamily
Phenotypes From GWAS Catalog for OR2H2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004930 | G protein-coupled receptor activity | IEA | -- |
| GO:0004984 | olfactory receptor activity | TAS,IEA | -- |
Phenotypes for OR2H2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR2H2 - Select products 50% OFF >
- * OR2H2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR2H2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR2H2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR2H2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR2H2
- Browse OriGene Inhibitory RNA Products For OR2H2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR2H2
Clone Products
- Applied Biological Materials (abm): Clones for OR2H2 - Select products 50% OFF >
- * OR2H2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR2H2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR2H2
Cell Line Products
-
Horizon Cell Lines for OR2H2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR2H2 Gene
Localization for OR2H2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for OR2H2 Gene
- Cell membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR2H2 Gene
Pathways & Interactions for OR2H2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Signaling by GPCR | ||
| 2 | Olfactory transduction | ||
| 3 | Peptide ligand-binding receptors | ||
Pathways by source for OR2H2 Gene
1 BioSystems pathway for OR2H2 Gene
4 Reactome pathways for OR2H2 Gene
1 KEGG pathway for OR2H2 Gene
Interacting Proteins for OR2H2 Gene
GPS-Prot Interaction Network for OR2H2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006952 | defense response | TAS | 7665158 |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G protein-coupled receptor signaling pathway | IEA | -- |
| GO:0007608 | sensory perception of smell | IEA | -- |
| GO:0007618 | mating | TAS | 7665158 |
No data available for SIGNOR curated interactions for OR2H2 Gene
Transcripts for OR2H2 Gene
mRNA/cDNA for OR2H2 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000383640 1514 nts (view in UCSC)
- ENST00000641840 3061 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for OR2H2 - Select products 50% OFF >
- * OR2H2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for OR2H2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR2H2
-
Santa Cruz Biotechnology (SCBT) CRISPR for OR2H2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR2H2
- Browse OriGene Inhibitory RNA Products For OR2H2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR2H2
Clone Products
- Applied Biological Materials (abm): Clones for OR2H2 - Select products 50% OFF >
- * OR2H2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for OR2H2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR2H2
Relevant External Links for OR2H2 Gene
- GeneLoc Exon Structure for
- OR2H2
Expression for OR2H2 Gene
mRNA differential expression in normal tissues according to GTEx for OR2H2 Gene
This gene is overexpressed in Testis (x6.4), Brain - Putamen (basal ganglia) (x5.1), Brain - Nucleus accumbens (basal ganglia) (x5.0), and Brain - Caudate (basal ganglia) (x4.4).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR2H2
SOURCE GeneReport for Unigene cluster for OR2H2 Gene:
Hs.529493Evidence on tissue expression from TISSUES for OR2H2 Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for OR2H2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR2H2 Gene
Orthologs for OR2H2 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LOC100615382 30 |
|
||
| OR2H2 31 |
|
OneToOne | |||
| Rat (Rattus norvegicus) |
Mammalia | Olr1750 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Or2h2 46 Olfr90 30 17 |
|
|
|
| Olfr132 31 |
|
ManyToMany | |||
| Or2h2b-ps 46 Olfr753-ps1 |
|
|
|||
| Or2h2c 46 Olfr92 |
|
|
|||
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany |
- Species where no ortholog for OR2H2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for OR2H2 Gene
- ENSEMBL:
- Gene Tree for OR2H2 (if available)
- TreeFam:
- Gene Tree for OR2H2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for OR2H2: view image
Paralogs for OR2H2 Gene
Paralogs for OR2H2 Gene
- OR2H1 5
- OR2C1 5
- OR2G3 5
- OR2B2 5
- OR2B6 5
- OR2W3 5
- OR2G6 5
- OR2J1 5
- OR2J3 5
- OR2J2 5
- OR2B11 5
- OR2G2 5
- OR2C3 5
- GCSAML-AS1 5
- OR2W1 5
- OR2Y1 5
- OR2B3 5
- OR2I1P 5
- OR2S2 5
- OR2D2 5
- OR2D3 5
- OR2F1 5
- OR5V1 5
- OR13C3 5
- OR13C4 5
- OR2V1 5
- OR2F2 5
- OR10C1 5
- OR13C9 5
- OR2K2 5
- OR10A5 5
- OR13C8 5
- OR13C5 5
- OR13C2 5
- OR13D1 5
- OR13J1 5
- OR6A2 5
- OR10A2 5
- OR10A4 5
- OR10A7 5
- OR10AG1 5
- OR2V2 5
- OR10P1 5
- OR10G6 5
- OR2T33 5
- OR2T12 5
- OR2T35 5
- OR13H1 5
- OR10G2 5
- OR10A6 5
- OR10D3 5
- OR2T8 5
- OR2AK2 5
- OR2M2 5
- OR2T4 5
- OR2T2 5
- OR2T5 5
- OR2T29 5
- OR2AE1 5
- OR6Y1 5
- OR2Z1 5
- OR10A3 5
- OR10G4 5
- OR2AJ1 5
- OR2L8 5
- OR2L5 5
- OR2L2 5
- OR2L3 5
- OR2M5 5
- OR2M3 5
- OR2M4 5
- OR2M7 5
- OR2T3 5
- OR2T34 5
- OR2T10 5
- OR2T27 5
- OR10H1 5
- OR10G3 5
- OR2AG2 5
- OR2AG1 5
- OR10S1 5
- OR10G9 5
- OR10G7 5
- OR2T1 5
- OR2T11 5
- OR6B1 5
- OR10H5 5
- OR10G8 5
- OR2L13 5
- OR2T6 5
- OR10AD1 5
- OR10H2 5
- OR13C7 5
(449) SIMAP similar genes for OR2H2 Gene using alignment to 1 proteins:
- OR2H2_HUMAN
- OR2H1
- 6M1-16
- OR2H5P
- OLFR 42A
- OLFR 42B
- OR2G3
- OR2W6P
- OR2B2
- OR2J4P
- OR2J3
- OR2B11
- OR2G2
- OR2C3
- OR2B8P
- OR2B6
- OR2W5
- OR2W1
- OR2J1
- OR2G6
- OR2C1
- OR2B3
- OR2W3
- OR2K2
- OR2J2
- OR7-140
- OR2Y1
- olfr89
- OR7-139
- OR5V1
- OR2V2
- OR2M7
- OR2M5
- OR2M2
- OR2I1P
- OR2T7
- OR2F2
- OR2F1
- OR13H1
- OR13D1
- OR13C3
- OR13C2
- OR2AG2
- OR13F1
- OR5W2
- OR5AP2
- OR2T33
- OR2T12
- OR2S2
- OR2M3
- OR2V1
- OR2D2
- OR2AJ1
- OR2A5
- OR2A12
- OR1M1
- OR10R3P
- OR10P1
- OR10J4
- OR10A7
- OR8U9
- OR7G3
- OR7A10
- OR5T1
- OR5M10
- OR5C1
- OR5B21
- OR5A2
- OR2T8
- OR2T5
- OR2T35
- OR2T29
- OR2T27
- OR2T2
- OR2T11
- OR2T10
- OR2M4
- OR10J1
- OR2D3
- OR2AG1
- OR2AE1
- OR2A2
- OR13J1
- OR13C9
- OR13C8
- OR13C5
- OR13C4
- OR10AG1
- OR10A6
- OR9I1
- OR8U8
- OR8U1
- OR8B3
- OR8B12
- OR5T3
- OR5M11
- OR5J2
- OR5AN1
- OR5AC1
- OR5A1
- OR4Q2
- OR4D5
- OR2Z1
- OR2T4
- OR2T34
- OR2T3
- OR2T1
- OR2L2
- OR1D2
- OR10J3
- OR2AK2
- OR2A42
- OR2A14
- OR1L6
- OR1L4
- OR1C1
- OR13A1
- OR10D4P
- OR10A3
- OR10A2
- OR2A1
- OR7A5
- OR6C74
- OR7D4
- OR9Q2
- OR9Q1
- OR8J2
- OR8I2
- OR8H1
- OR8G5
- OR8G1
- OR8D1
- OR8B8
- OR8B2
- OR7G2
- OR7D2
- OR7C1
- OR7A2P
- OR7A17
- OR6N2
- OR6N1
- OR6C6
- OR6B1
- OR5R1
- OR5M1
- OR5L2
- OR5L1
- OR5I1
- OR5G3
- OR5F1
- OR5D16
- OR5AR1
- OR5AL1
- OR4M1
- OR4K2
- OR4K1
- OR4E2
- OR4B1
- OR2T6
- OR2L8
- OR3A3
- OR3A1
- OR10A4
- OR2A25
- OR1S2
- OR1S1
- OR1N2
- OR1J4
- OR1J1
- OR1F2P
- OR1F12
- OR1F1
- OR17-16
- OR12D3
- OR11A1
- OR10Z1
- OR10K1
- OR10J5
- OR10H2
- OR10H1
- OR10G7
- OR10AD1
- OR8G2
- OR1D5
- OR9G4
- OR8J3
- OR8H3
- OR8D2
- OR7C2
- OR6Y1
- OR6C65
- OR5T2
- OR5P3
- OR5M8
- OR5M3
- OR5K2
- OR5B3
- OR5B2
- OR5B12
- OR5AU1
- OR5AS1
- OR5AC2
- OR4M2
- OR4K17
- OR4E1
- OR4D1
- OR4C3
- OR4C15
- OR3A2
- OR2L5
- OR2L3
- OR2L13
- OR8J1
- OR5K1
- OR4S2
- OR1L1
- OR1A1
- OR1L8
- OR1K1
- OR1J2
- OR1I1
- OR1D4
- OR17-137
- OR13G1
- OR12D2
- OR10R2
- OR10H5
- OR10G9
- OR10G6
- OR10G4
- OR10G2
- OR10C1
- OR10A5
- LOC441453
- OR8K5
- OR8B4
- OR8A1
- OR7G1
- OR7E86P
- OR7E85P
- OR7E24
- OR6P1
- OR6C75
- OR6C70
- OR6C68
- OR6C3
- OR5M9
- OR5H6
- OR5D18
- OR5AK3P
- OR4Q3
- OR4N5
- OR4F6
- OR4F3
- OR4F29
- OR4F21
- OR4F16
- OR4F15
- OR4C46
- OR4C13
- OR2AP1
- OR1Q1
- OR1P1
- OR1N1
- OR1L3
- OR1E3P
- OR1E1
- OR16-89
- OR16-37
- OR14J1
- OR11L1
- OR11G2
- OR10X1
- OR10T2
- OR10S1
- OR10Q1
- OR10G8
- OR10G3
- OR6Q1
- OR6B3
- tpcr110
- OR9K2
- OR9G9
- OR9G1
- OR9A4
- OR8S1
- OR8K3
- OR8K1
- OR8H2
- OR8D4
- OR7E5P
- OR6X1
- OR6T1
- OR6S1
- OR6M1
- OR6C76
- OR6C2
- OR6C1
- OR6B2
- OR6A2
- OR5P2
- OR5K4
- OR5H2
- OR5E1P
- OR5D13
- OR5B17
- OR5AK2
- OR4S1
- OR4N4
- OR4N2
- OR4K13
- OR4F4
- OR4F17
- OR4D2
- OR4A4P
- OR4A47
- OR4A15
- OR4A5
- OR10AC1P
- OR2A7
- OR2A4
- OR1G1
- OR1E3
- OR1E2
- OR1A2
- OR17-15
- OR17-130
- OR16-90
- OR16-88
- OR16-36
- OR14A2
- OR11H7
- OR11H6
- OR11H12
- OR10W1
- OR10V1
- OR10J6P
- OR10H4
- OR10D3
- JCG4
- HSA10
- OR5H14
- OR10K2
- PJCG2
- PJCG1
- OR7E35P
- OR6K3
- OR6C4
- OR5K3
- OR5H15
- OR5H1
- OR4X2
- OR4P4
- OR4L1
- OR4K3
- OR4K14
- OR4F5
- OR4D6
- OR4D11
- OR4D10
- OR4C12
- OR4C11
- OR3A4P
- OR14L1P
- OR14A16
- OR11H4
- OR11H2
- OR11H1
- OR10H3
- HSA12
- OR9A2
- OR6V1
- OR6J1
- OR6F1
- OR5D3
- OR5D14
- OR4K5
- OR4K15
- OR4D9
- OR4C6
- OR4C5
- OR9A1P
- OR1B1
- OR11H13P
- FKSG35
- OR6K2
- OR4X1
- OR4A8P
- OR4A16
- OR14C36
- OR6K6
- OR52K3P
- OR52L1
- OR2AT4
- OR14K1
- OR14I1
- OR7E18P
- OR56B2P
- OR56B1
- OR52L2P
- OR56A4
- OR56A1
- OR4C45
- OR56A3
- OR52E8
- OR4C16
- OR52K1
- OR51M1
- OR52I2
- OR52I1
- OR52E6
- OR52D1
- OR56A5
- OR52K2
- OR56B4
- OR52P1P
- OR52E4
- OR51E2
- OR51E1
- OR51B6
- OR52R1
- OR52E2
- OR52N2
- OR56B3P
- OR52Z1
- OR52J3
- OR52E1
- OR51Q1
- OR51A4
- OR51A1P
- OR51I2
- OR52N5
- OR52N1
- OR52M1
- OR52B6
- OR52B2
- OR52N4
- OR51B5
- OR51B2
- OR52H1
- OR52B4
- OR51V1
- OR51T1
- OR51S1
- OR51L1
- OR51I1
- OR51F2
- OR51B4
- OR51A7
- OR52E5
Variants for OR2H2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for OR2H2 Gene
| SNP ID | Clinical significance and condition | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs3129034 | -. - | p.Leu30Ilep.Leu30Phe | |||
| rs11966382 | - | p.Val38Met | |||
| rs1233387 | - | p.Ala48Val | |||
| rs141430371 | - | p.Thr220Ala | |||
| VAR_010227 | - | p.Leu30Ser |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759411 | CNV | gain+loss | 17122850 |
| esv3608481 | CNV | loss | 21293372 |
| nsv1074389 | CNV | deletion | 25765185 |
| nsv1122126 | CNV | deletion | 24896259 |
| nsv1145096 | CNV | deletion | 24896259 |
| nsv519288 | CNV | loss | 19592680 |
| nsv5239 | CNV | deletion | 18451855 |
| nsv970099 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
90.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.63;
86.28% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for OR2H2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- OR2H2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR2H2 Gene
Disorders for OR2H2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acute pulmonary heart disease |
|
|
| acute cor pulmonale |
|
|
| intestinal tuberculosis |
|
|
| gastrointestinal tuberculosis |
|
|
| abdominal tuberculosis |
|
|
Search OR2H2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for OR2H2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for OR2H2 Gene
Publications for OR2H2 Gene
- Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors. (PMID: 19833159) Thompson EE … Ober C (Human immunology 2010) 3 41
- High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos LF … Criswell LA (PLoS genetics 2009) 3 41
- SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians. (PMID: 17971048) Burfoot RK … Rubio JP (Tissue antigens 2008) 3 41
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4
ExternalLinks
Products for OR2H2 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for OR2H2
- Search Origene for MassSpec and Protein Over-expression Lysates for OR2H2
- Origene Custom Protein Services for OR2H2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for OR2H2
- Browse OriGene Inhibitory RNA Products For OR2H2
- OriGene qPCR primer pairs for OR2H2
- OriGene CRISPR knockouts for OR2H2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For OR2H2
- Sino Biological Human cDNA Clone for OR2H2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals lysates for OR2H2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for OR2H2 (AFLGC-OR2H2)
- VectorBuilder Custom and pre-made DNA vectors for OR2H2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for OR2H2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for OR2H2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for OR2H2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for OR2H2
- antibodies-online: Show 18 available OR2H2 Antibodies ranked by validation data
- Compare Top OR2H2 Antibodies
- antibodies-online: Show 10 available OR2H2 Elisa Kits ranked by validation data
- Compare Top OR2H2 Elisa Kits
- antibodies-online: Search results for available OR2H2 related products ranked by validation data
- Horizon Cell Lines for OR2H2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for OR2H2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for OR2H2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for OR2H2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR2H2
- Boster Bio Antibodies for OR2H2
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for OR2H2
Sources for OR2H2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB