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Aliases for OR1J4 Gene

Aliases for OR1J4 Gene

  • Olfactory Receptor Family 1 Subfamily J Member 4 2 3 5
  • Olfactory Receptor OR9-21 3 4
  • HTPCRX01 3 4
  • Olfactory Receptor, Family 1, Subfamily J, Member 4 2
  • Olfactory Receptor 1J4 3
  • HSHTPCRX01 3
  • OR9-21 3

External Ids for OR1J4 Gene

Previous GeneCards Identifiers for OR1J4 Gene

  • GC09P116386
  • GC09U900014
  • GC09P118735
  • GC09P120614
  • GC09P122360
  • GC09P124313
  • GC09P125281

Summaries for OR1J4 Gene

Entrez Gene Summary for OR1J4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1J4 Gene

OR1J4 (Olfactory Receptor Family 1 Subfamily J Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR1J2.

UniProtKB/Swiss-Prot for OR1J4 Gene

  • Odorant receptor.

Gene Wiki entry for OR1J4 Gene

Additional gene information for OR1J4 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR1J4 Gene

Genomics for OR1J4 Gene

GeneHancer (GH) Regulatory Elements for OR1J4 Gene

Promoters and enhancers for OR1J4 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J123385 Enhancer 0.9 ENCODE 14.6 +866.4 866416 0.2 HDGF PKNOX1 ATF1 SIN3A GLI4 ZNF2 GLIS2 ARID2 ZNF143 RUNX3 OR1J4 ENSG00000233616 TLK1P1 OR1J2 GC09P123401 CRB2 DENND1A
GH09J122463 Enhancer 1.1 Ensembl ENCODE 10.4 -54.3 -54334 1.9 PKNOX1 SMAD1 ARID4B ZNF2 BRCA1 YY1 ARID2 ZNF143 ATF7 DEK OR1Q1 OR1K1 OR1N1 OR1J4 PTGS1 OR5C1 RBM18 MRRF TTLL11 ENSG00000231465
GH09J122580 Enhancer 0.8 ENCODE 10.2 +61.4 61396 0.2 TAF9B CHAMP1 FOS GATAD2B ZEB2 ZNF592 SP1 NFIC MAFF GMEB1 OR1N2 OR1B1 OR1N1 OR1J4 OR1J2 OR1K1 OR1Q1 OR1H1P OR1L8
GH09J122499 Enhancer 0.6 ENCODE 11.1 -20.1 -20064 0.1 CTCF PKNOX1 TFAP4 ZNF654 FOXA2 TRIM22 MAX REST RAD21 FOXA1 PIR39690 OR1J4 OR1N1 ENSG00000231465 OR1N2 OR5C1 OR1J1 OR1J2
GH09J122766 Enhancer 0.2 FANTOM5 15.9 +247.9 247864 0.4 OR1J4 OR1N2 OR1L8 OR1K1 OR5C1 OR1Q1 OR1J2 OR1L1 OR1B1 OR1L4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR1J4 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR1J4 gene promoter:
  • SREBP-1c
  • SREBP-1b
  • SREBP-1a
  • C/EBPalpha
  • Nkx3-1 v3
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v4
  • AML1a

Genomic Locations for OR1J4 Gene

Genomic Locations for OR1J4 Gene
942 bases
Plus strand
942 bases
Plus strand

Genomic View for OR1J4 Gene

Genes around OR1J4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1J4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1J4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1J4 Gene

Proteins for OR1J4 Gene

  • Protein details for OR1J4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 1J4
    Protein Accession:
    Secondary Accessions:
    • A3KFM0
    • Q6IEZ3
    • Q96R89

    Protein attributes for OR1J4 Gene

    313 amino acids
    Molecular mass:
    34959 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR1J4 Gene

Post-translational modifications for OR1J4 Gene

Other Protein References for OR1J4 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR1J4 Gene

Domains & Families for OR1J4 Gene

Gene Families for OR1J4 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR1J4 Gene

Suggested Antigen Peptide Sequences for OR1J4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1J4: view

Function for OR1J4 Gene

Molecular function for OR1J4 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR1J4: view
genes like me logo Genes that share phenotypes with OR1J4: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR1J4

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1J4 Gene

Localization for OR1J4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1J4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR1J4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR1J4: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR1J4 Gene

Pathways & Interactions for OR1J4 Gene

genes like me logo Genes that share pathways with OR1J4: view

Pathways by source for OR1J4 Gene

Gene Ontology (GO) - Biological Process for OR1J4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1J4: view

No data available for SIGNOR curated interactions for OR1J4 Gene

Drugs & Compounds for OR1J4 Gene

No Compound Related Data Available

Transcripts for OR1J4 Gene

mRNA/cDNA for OR1J4 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR1J4 Gene

Olfactory receptor, family 1, subfamily J, member 4:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for OR1J4

Alternative Splicing Database (ASD) splice patterns (SP) for OR1J4 Gene

No ASD Table

Relevant External Links for OR1J4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR1J4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR1J4 Gene

mRNA differential expression in normal tissues according to GTEx for OR1J4 Gene

This gene is overexpressed in Testis (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of OR1J4 Gene:


SOURCE GeneReport for Unigene cluster for OR1J4 Gene:

genes like me logo Genes that share expression patterns with OR1J4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR1J4 Gene

Orthologs for OR1J4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR1J4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC473041 33
  • 99.57 (n)
OR1J4 34
  • 99 (a)
(Bos Taurus)
Mammalia LOC508604 33
  • 86.26 (n)
-- 34
  • 83 (a)
-- 34
  • 82 (a)
-- 34
  • 81 (a)
-- 34
  • 77 (a)
-- 34
  • 76 (a)
-- 34
  • 75 (a)
(Mus musculus)
Mammalia Or1j4 51 Olfr350 16 34 33
  • 83.76 (n)
Or1j12 51 Olfr340
  • chr2:36,452,587-36,453,522
Or1j13 51 Olfr341
  • chr2:36,479,190-36,480,128
Or1j14 51 Olfr342
  • chr2:36,527,414-36,528,349
Or1j15 51 Olfr344
  • chr2:36,568,600-36,569,526
Or1j16 51 Olfr345
  • chr2:36,640,041-36,640,973
Or1j18 51 Olfr347
  • chr2:36,734,323-36,735,258
Or1j19 51 Olfr348
  • chr2:36,786,527-36,787,465
Or1j21 51 Olfr50
  • chr2:36,793,238-36,794,173
Or1j23-ps 51 Olfr717-ps1
  • chr13:106,197,238-106,197,780
Or1j8 51 Olfr335
  • chr2:36,301,628-36,302,476
(Rattus norvegicus)
Mammalia Olr413 33
  • 83.55 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 73 (a)
Species where no ortholog for OR1J4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR1J4 Gene

Gene Tree for OR1J4 (if available)
Gene Tree for OR1J4 (if available)
Evolutionary constrained regions (ECRs) for OR1J4: view image

Paralogs for OR1J4 Gene

Paralogs for OR1J4 Gene

(459) SIMAP similar genes for OR1J4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR1J4: view

Variants for OR1J4 Gene

Sequence variations from dbSNP and Humsavar for OR1J4 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1002399897 -- 122,518,850(+) T/C upstream_transcript_variant
rs1003299656 -- 122,520,166(+) G/A downstream_transcript_variant
rs1004383994 -- 122,517,411(+) A/G upstream_transcript_variant
rs1006242716 -- 122,518,536(+) A/G upstream_transcript_variant
rs1006875356 -- 122,518,172(+) T/C upstream_transcript_variant

Variation tolerance for OR1J4 Gene

Residual Variation Intolerance Score: 70% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.19; 23.88% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR1J4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR1J4 Gene

Disorders for OR1J4 Gene

Additional Disease Information for OR1J4

No disorders were found for OR1J4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR1J4 Gene

Publications for OR1J4 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M … Perret J (Nature 1992) 2 3 4 58
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 58
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for OR1J4 Gene

Sources for OR1J4 Gene

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