Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR1F2P Gene

Aliases for OR1F2P Gene

  • Olfactory Receptor Family 1 Subfamily F Member 2 Pseudogene 2 3 5
  • Olfactory Receptor, Family 1, Subfamily F, Member 2 2 3
  • OLFMF2 2 3
  • OR1F2 3 4
  • Olfactory Receptor, Family 1, Subfamily F, Member 2, Pseudogene 2
  • Olfactory Receptor, Family 1, Subfamily F, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 1, Subfamily F, Member 11 3
  • Olfactory Receptor OR16-3 Pseudogene 3
  • Putative Olfactory Receptor 1F2 4
  • OR16-3 3
  • OR1F11 3
  • OR1F3P 3
  • OR1F2P 5
  • OLFmf2 4
  • Hg91 3

External Ids for OR1F2P Gene

Previous HGNC Symbols for OR1F2P Gene

  • OR1F3P
  • OR1F2

Previous GeneCards Identifiers for OR1F2P Gene

  • GC16P003266
  • GC16P003207
  • GC16P003267
  • GC16P003271
  • GC16P003219
  • GC16P003251
  • GC16P003772
  • GC16P003850
  • GC16P003900
  • GC16P004075
  • GC16P003289
  • GC16P003328
  • GC16P003353
  • GC16P003400
  • GC16P003449
  • GC16P003482
  • GC16P003570
  • GC16P003616
  • GC16P004263
  • GC16P004505

Summaries for OR1F2P Gene

Entrez Gene Summary for OR1F2P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR1F2P Gene

OR1F2P (Olfactory Receptor Family 1 Subfamily F Member 2 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot Summary for OR1F2P Gene

Gene Wiki entry for OR1F2P Gene

Additional gene information for OR1F2P Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR1F2P Gene

Genomics for OR1F2P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR1F2P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J003214 Enhancer 0.7 Ensembl ENCODE 250.7 +0.3 339 4.6 EZH2 FOXA2 RXRB HLF FOXA3 HMBOX1 CBFA2T3 OR1F2P lnc-ZNF200-3 MEFV ZNF200 TIGD7 ZNF75A NAA60 ZNF597 ZNF174 ZSCAN32
GH16J003213 Enhancer 0.3 Ensembl 0.7 -2.3 -2261 0.2 ZNF512 CLUAP1 ZNF200 ZNF75A TIGD7 NAA60 ZNF597 ZNF174 ZSCAN32 OR2C1 C16orf90
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR1F2P on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the OR1F2P gene promoter:
  • HNF-4alpha1
  • HOXA9
  • HOXA9B
  • Meis-1
  • Meis-1a
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v3

Genomic Locations for OR1F2P Gene

Latest Assembly
chr16:3,215,562-3,216,546
(GRCh38/hg38)
Size:
985 bases
Orientation:
Plus strand

Previous Assembly
chr16:3,265,562-3,266,546
(GRCh37/hg19 by Entrez Gene)
Size:
985 bases
Orientation:
Plus strand

chr16:3,265,562-3,266,546
(GRCh37/hg19 by Ensembl)
Size:
985 bases
Orientation:
Plus strand

Genomic View for OR1F2P Gene

Genes around OR1F2P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR1F2P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR1F2P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR1F2P Gene

Proteins for OR1F2P Gene

  • Protein details for OR1F2P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96R84-OR1F2_HUMAN
    Recommended name:
    Putative olfactory receptor 1F2
    Protein Accession:
    Q96R84

    Protein attributes for OR1F2P Gene

    Size:
    312 amino acids
    Molecular mass:
    34944 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AJ003145; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for OR1F2P Gene

Post-translational modifications for OR1F2P Gene

No Post-translational modifications

Other Protein References for OR1F2P Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR1F2P Gene

Domains & Families for OR1F2P Gene

Gene Families for OR1F2P Gene

Protein Domains for OR1F2P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR1F2P Gene

GenScript: Design optimal peptide antigens:
  • OLFmf2 (OR1F2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q96R84

UniProtKB/Swiss-Prot:

OR1F2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR1F2P: view

Function for OR1F2P Gene

Molecular function for OR1F2P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
GENATLAS Biochemistry:
olfactory receptor,family 1,subfamily F,member 2,likely a pseudogene,G protein coupled receptor superfamily

Gene Ontology (GO) - Molecular Function for OR1F2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA 21873635
genes like me logo Genes that share ontologies with OR1F2P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR1F2P Gene

Localization for OR1F2P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR1F2P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR1F2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR1F2P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR1F2P Gene

Pathways & Interactions for OR1F2P Gene

PathCards logo

SuperPathways for OR1F2P Gene

genes like me logo Genes that share pathways with OR1F2P: view

Pathways by source for OR1F2P Gene

Gene Ontology (GO) - Biological Process for OR1F2P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR1F2P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR1F2P Gene

Drugs & Compounds for OR1F2P Gene

No Compound Related Data Available

Transcripts for OR1F2P Gene

mRNA/cDNA for OR1F2P Gene

2 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR1F2P Gene

No ASD Table

Relevant External Links for OR1F2P Gene

GeneLoc Exon Structure for
OR1F2P

Expression for OR1F2P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR1F2P Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OR1F2P Gene

This gene is overexpressed in Testis (x21.5), Brain - Cerebellar Hemisphere (x6.1), and Brain - Cerebellum (x5.0).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for OR1F2P

SOURCE GeneReport for Unigene cluster for OR1F2P Gene:

Hs.651203
genes like me logo Genes that share expression patterns with OR1F2P: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR1F2P Gene

Orthologs for OR1F2P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR1F2P Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Or1ab2 45 Olfr374
  • chr8:72,109,376-72,110,506
Or1w2 45 Olfr98
  • chr17:37,262,736-37,263,662
Species where no ortholog for OR1F2P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR1F2P Gene

ENSEMBL:
Gene Tree for OR1F2P (if available)
TreeFam:
Gene Tree for OR1F2P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR1F2P

Paralogs for OR1F2P Gene

(453) SIMAP similar genes for OR1F2P Gene using alignment to 1 proteins:

  • OR1F2_HUMAN
genes like me logo Genes that share paralogs with OR1F2P: view

No data available for Paralogs for OR1F2P Gene

Variants for OR1F2P Gene

Structural Variations from Database of Genomic Variants (DGV) for OR1F2P Gene

Variant ID Type Subtype PubMed ID
nsv1036149 CNV gain 25217958
nsv1044147 CNV loss 25217958
nsv457355 CNV gain 19166990
nsv471074 CNV gain 18288195
nsv509592 CNV insertion 20534489
nsv516280 CNV gain 19592680
nsv571249 CNV gain 21841781
nsv833127 CNV gain+loss 17160897

Additional Variant Information for OR1F2P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR1F2P
Leiden Open Variation Database (LOVD)
OR1F2P

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance and Variation tolerance for OR1F2P Gene

Disorders for OR1F2P Gene

Additional Disease Information for OR1F2P

No disorders were found for OR1F2P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR1F2P Gene

Publications for OR1F2P Gene

  1. A transcriptional Map of the FMF region. (PMID: 9653642) Bernot A … Weissenbach J (Genomics 1998) 2 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3
  5. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M … Perret J (Nature 1992) 3

Products for OR1F2P Gene

Sources for OR1F2P Gene