Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR14L1P Gene

Aliases for OR14L1P Gene

  • Olfactory Receptor Family 14 Subfamily L Member 1 Pseudogene 2 3 5
  • Olfactory Receptor, Family 5, Subfamily AV, Member 1 Pseudogene 2 3
  • OR5AV1P 3 4
  • Olfactory Receptor, Family 14, Subfamily L, Member 1 Pseudogene 2
  • Olfactory Receptor OR1-35 Pseudogene 3
  • Putative Olfactory Receptor 14L1 4
  • Putative Olfactory Receptor 5AV1 4
  • Olfactory Receptor OR1-36 3
  • OR14L1P 5
  • OR1-35 3
  • OR1-36 3
  • OR5AV1 3

External Ids for OR14L1P Gene

Previous HGNC Symbols for OR14L1P Gene

  • OR5AV1
  • OR5AV1P

Previous GeneCards Identifiers for OR14L1P Gene

  • GC01P245850
  • GC01P247782

Summaries for OR14L1P Gene

Entrez Gene Summary for OR14L1P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14L1P Gene

OR14L1P (Olfactory Receptor Family 14 Subfamily L Member 1 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR14A2.

UniProtKB/Swiss-Prot Summary for OR14L1P Gene

Additional gene information for OR14L1P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR14L1P Gene

Genomics for OR14L1P Gene

Genomic Locations for OR14L1P Gene

Latest Assembly
chr1:247,617,143-247,622,372
(GRCh38/hg38)
Size:
5,230 bases
Orientation:
Plus strand

Previous Assembly
chr1:247,782,983-247,783,861
(GRCh37/hg19 by Entrez Gene)
Size:
879 bases
Orientation:
Plus strand

chr1:247,782,945-247,783,872
(GRCh37/hg19 by Ensembl)
Size:
928 bases
Orientation:
Plus strand

Genomic View for OR14L1P Gene

Genes around OR14L1P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR14L1P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR14L1P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR14L1P Gene

No data available for GeneHancer (GH) Regulatory Elements for OR14L1P Gene

Proteins for OR14L1P Gene

  • Protein details for OR14L1P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHC6-O14L1_HUMAN
    Recommended name:
    Putative olfactory receptor 14L1
    Protein Accession:
    Q8NHC6
    Secondary Accessions:
    • Q5JQT0

    Protein attributes for OR14L1P Gene

    Size:
    308 amino acids
    Molecular mass:
    34709 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR14L1P Gene

Post-translational modifications for OR14L1P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR14L1P Gene

ENSEMBL proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR14L1P Gene

Domains & Families for OR14L1P Gene

Gene Families for OR14L1P Gene

Protein Domains for OR14L1P Gene

InterPro:
Blocks:
  • Olfactory receptor signature

Suggested Antigen Peptide Sequences for OR14L1P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 5AV1 (O14L1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NHC6

UniProtKB/Swiss-Prot:

O14L1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR14L1P: view

Function for OR14L1P Gene

Molecular function for OR14L1P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR14L1P Gene

Gene Ontology (GO) - Molecular Function for OR14L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G protein-coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA,IBA 21873635
GO:0005549 odorant binding IBA 21873635
genes like me logo Genes that share ontologies with OR14L1P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR14L1P Gene

Localization for OR14L1P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14L1P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR14L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR14L1P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR14L1P Gene

Pathways & Interactions for OR14L1P Gene

PathCards logo

SuperPathways for OR14L1P Gene

genes like me logo Genes that share pathways with OR14L1P: view

Pathways by source for OR14L1P Gene

Gene Ontology (GO) - Biological Process for OR14L1P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G protein-coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14L1P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR14L1P Gene

Drugs & Compounds for OR14L1P Gene

No Compound Related Data Available

Transcripts for OR14L1P Gene

mRNA/cDNA for OR14L1P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR14L1P Gene

No ASD Table

Relevant External Links for OR14L1P Gene

GeneLoc Exon Structure for
OR14L1P

Expression for OR14L1P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR14L1P Gene

mRNA differential expression in normal tissues according to GTEx for OR14L1P Gene

This gene is overexpressed in Testis (x14.1).
genes like me logo Genes that share expression patterns with OR14L1P: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR14L1P Gene

Orthologs for OR14L1P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for OR14L1P Gene

Organism Taxonomy Gene Similarity Type Details
Mouse
(Mus musculus)
Mammalia Or14m1-ps 45 Olfr1398-ps1
  • chr3:52,236,841-52,237,524
Or14p1 45 Olfr465
  • chr13:65,144,261-65,145,205
Species where no ortholog for OR14L1P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for OR14L1P Gene

ENSEMBL:
Gene Tree for OR14L1P (if available)
TreeFam:
Gene Tree for OR14L1P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR14L1P

Paralogs for OR14L1P Gene

(438) SIMAP similar genes for OR14L1P Gene using alignment to 1 proteins:

  • O14L1_HUMAN
genes like me logo Genes that share paralogs with OR14L1P: view

Variants for OR14L1P Gene

Additional Variant Information for OR14L1P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR14L1P
Leiden Open Variation Database (LOVD)
OR14L1P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR14L1P Gene

Disorders for OR14L1P Gene

No disorders were found for OR14L1P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR14L1P Gene

Publications for OR14L1P Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  3. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang SJ … Fox CS (BMC medical genetics 2007) 40
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3

Products for OR14L1P Gene

Sources for OR14L1P Gene