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Aliases for OR14J1 Gene

Aliases for OR14J1 Gene

  • Olfactory Receptor Family 14 Subfamily J Member 1 2 3 5
  • Olfactory Receptor OR6-25 3 4
  • Olfactory Receptor 5U1 3 4
  • Hs6M1-28 3 4
  • OR5U1 3 4
  • Olfactory Receptor, Family 14, Subfamily J, Member 1 2
  • Olfactory Receptor, Family 5, Subfamily U, Member 1 2
  • Olfactory Receptor, Family 5, Subfamily U Member 1 3
  • Olfactory Receptor 14J1 3
  • BA150A6.4 3
  • OR6-25 3

External Ids for OR14J1 Gene

Previous HGNC Symbols for OR14J1 Gene

  • OR5U1

Previous GeneCards Identifiers for OR14J1 Gene

  • GC06P029384
  • GC06Po29204

Summaries for OR14J1 Gene

Entrez Gene Summary for OR14J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR14J1 Gene

OR14J1 (Olfactory Receptor Family 14 Subfamily J Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR14A16.

UniProtKB/Swiss-Prot for OR14J1 Gene

  • Odorant receptor.

Gene Wiki entry for OR14J1 Gene

Additional gene information for OR14J1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR14J1 Gene

Genomics for OR14J1 Gene

GeneHancer (GH) Regulatory Elements for OR14J1 Gene

Promoters and enhancers for OR14J1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J030065 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 14.6 +765.1 765104 3 ZFP64 DMAP1 YBX1 YY1 SLC30A9 E2F8 ZNF143 ZNF263 SP3 NFYC PPP1R11 TRIM39 ZNRD1 HCG4P3 TRIM26 PPP1R10 NRM MDC1 HLA-A RPL7P4
GH06J028586 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 14.6 -714.5 -714536 1.9 FOXA2 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF143 SP3 TRQ-TTG2-1 ZBED9 GPX6 GPX5 ZKSCAN3 ZNF311 ZNF603P ZSCAN12 ZNF90P2 KRT18P1
GH06J028814 Enhancer 0.9 FANTOM5 4.7 -487.3 -487323 0.1 ZSCAN4 KLF17 ZBTB40 ZNF2 ETS1 ZNF335 ZNF213 ZNF366 KLF7 EGR2 ZNF311 ZKSCAN3 ZFP57 ZBED9 ZNF602P OR14J1 GPX6 OR2W1 OR2J3 OR2B3
GH06J029467 Enhancer 0.2 FANTOM5 11.2 +166.0 165998 0.3 GC06M029436 OR10C1 ZFP57 MAS1L OR11A1 OR14J1 OR2W1 OR2J3 OR2B3 OR12D2
GH06J029477 Enhancer 0.5 FANTOM5 1.7 +176.4 176397 0.6 MITF VEZF1 E2F5 MAS1L OR12D3 OR5V1 UBD LINC01015 OR2H2 OR14J1 MAS1LP1 LOC105375008
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR14J1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR14J1 gene promoter:
  • Meis-1b
  • Meis-1
  • HOXA9B
  • HOXA9
  • NF-1
  • NF-1/L
  • C/EBPalpha
  • SREBP-1a
  • SREBP-1b
  • SREBP-1c

Genomic Locations for OR14J1 Gene

Genomic Locations for OR14J1 Gene
11,317 bases
Plus strand
1,117 bases
Plus strand

Genomic View for OR14J1 Gene

Genes around OR14J1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR14J1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR14J1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR14J1 Gene

  • Protein details for OR14J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 14J1
    Protein Accession:
    Secondary Accessions:
    • A2BEC2
    • B0V078
    • Q5ST27

    Protein attributes for OR14J1 Gene

    321 amino acids
    Molecular mass:
    35892 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR14J1 Gene

Post-translational modifications for OR14J1 Gene

Other Protein References for OR14J1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR14J1 Gene

Domains & Families for OR14J1 Gene

Gene Families for OR14J1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR14J1 Gene

Suggested Antigen Peptide Sequences for OR14J1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR14J1: view

Function for OR14J1 Gene

Molecular function for OR14J1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR14J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR14J1: view
genes like me logo Genes that share phenotypes with OR14J1: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR14J1 Gene

Localization for OR14J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR14J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR14J1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR14J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR14J1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR14J1 Gene

Pathways & Interactions for OR14J1 Gene

genes like me logo Genes that share pathways with OR14J1: view

Pathways by source for OR14J1 Gene

1 BioSystems pathway for OR14J1 Gene
1 KEGG pathway for OR14J1 Gene

Interacting Proteins for OR14J1 Gene

Gene Ontology (GO) - Biological Process for OR14J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA,IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR14J1: view

No data available for SIGNOR curated interactions for OR14J1 Gene

Drugs & Compounds for OR14J1 Gene

No Compound Related Data Available

Transcripts for OR14J1 Gene

mRNA/cDNA for OR14J1 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR14J1 Gene

Olfactory receptor, family 14, subfamily J, member 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR14J1 Gene

No ASD Table

Relevant External Links for OR14J1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR14J1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR14J1 Gene

mRNA differential expression in normal tissues according to GTEx for OR14J1 Gene

This gene is overexpressed in Testis (x46.4).

NURSA nuclear receptor signaling pathways regulating expression of OR14J1 Gene:


SOURCE GeneReport for Unigene cluster for OR14J1 Gene:

genes like me logo Genes that share expression patterns with OR14J1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR14J1 Gene

Orthologs for OR14J1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR14J1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC471935 33
  • 99.38 (n)
OR14J1 34
  • 99 (a)
(Bos Taurus)
Mammalia LOC510530 33
  • 88.68 (n)
OR14J1 34
  • 67 (a)
(Canis familiaris)
Mammalia LOC100856296 33
  • 85.83 (n)
-- 34
  • 83 (a)
-- 34
  • 83 (a)
(Mus musculus)
Mammalia Or14j1 51 Olfr125 16 34 33
  • 81.77 (n)
Or14j10 51 Olfr116
  • chr17:37,623,671-37,624,633
Or14j2 51 Olfr113
  • chr17:37,574,486-37,575,496
Or14j3 51 Olfr114
  • chr17:37,589,416-37,590,351
Or14j4 51 Olfr115
  • chr17:37,609,820-37,610,830
Or14j5 51 Olfr126
  • chr17:37,850,594-37,851,550
Or14j6 51 Olfr127
  • chr17:37,903,548-37,904,516
Or14j7 51 Olfr128
  • chr17:37,923,457-37,924,491
Or14j8 51 Olfr761
  • chr17:37,952,054-37,953,022
Or14j9 51 Olfr112
  • chr17:37,563,350-37,564,384
Or14q1-ps 51 Olfr756-ps1
  • chr17:37,285,147-37,286,045
(Rattus norvegicus)
Mammalia Olr1693 33
  • 80.94 (n)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 57 (a)
-- 34
  • 47 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 55 (a)
(Gallus gallus)
Aves LOC101747306 33
  • 62.35 (n)
Species where no ortholog for OR14J1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR14J1 Gene

Gene Tree for OR14J1 (if available)
Gene Tree for OR14J1 (if available)
Evolutionary constrained regions (ECRs) for OR14J1: view image

Paralogs for OR14J1 Gene

Paralogs for OR14J1 Gene

(439) SIMAP similar genes for OR14J1 Gene using alignment to 1 proteins:

  • O14J1_HUMAN
genes like me logo Genes that share paralogs with OR14J1: view

Variants for OR14J1 Gene

Sequence variations from dbSNP and Humsavar for OR14J1 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1002701915 -- 29,305,147(+) G/T upstream_transcript_variant
rs1002791118 -- 29,305,858(+) A/G upstream_transcript_variant
rs1003128713 -- 29,306,092(+) A/G upstream_transcript_variant
rs1006360769 -- 29,305,064(+) A/C upstream_transcript_variant
rs1006668714 -- 29,308,118(+) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR14J1 Gene

Variant ID Type Subtype PubMed ID
dgv10338n54 CNV gain 21841781
esv3608473 CNV gain 21293372
nsv1015796 CNV gain 25217958
nsv1020683 CNV gain 25217958
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1145096 CNV deletion 24896259
nsv830624 CNV loss 17160897

Variation tolerance for OR14J1 Gene

Residual Variation Intolerance Score: 63.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.71; 32.53% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR14J1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR14J1 Gene

Disorders for OR14J1 Gene

Additional Disease Information for OR14J1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for OR14J1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR14J1 Gene

Publications for OR14J1 Gene

  1. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos LF … Criswell LA (PLoS genetics 2009) 3 44 58
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for OR14J1 Gene

Sources for OR14J1 Gene

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