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Aliases for OR13G1 Gene

Aliases for OR13G1 Gene

  • Olfactory Receptor Family 13 Subfamily G Member 1 2 3 5
  • Olfactory Receptor OR1-37 3 4
  • Olfactory Receptor, Family 13, Subfamily G, Member 1 2
  • Olfactory Receptor 13G1 3
  • OR1-37 3

External Ids for OR13G1 Gene

Previous GeneCards Identifiers for OR13G1 Gene

  • GC01U990418
  • GC01M244161
  • GC01M245902
  • GC01M247835

Summaries for OR13G1 Gene

Entrez Gene Summary for OR13G1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13G1 Gene

OR13G1 (Olfactory Receptor Family 13 Subfamily G Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is OR13A1.

UniProtKB/Swiss-Prot for OR13G1 Gene

  • Odorant receptor.

Gene Wiki entry for OR13G1 Gene

Additional gene information for OR13G1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13G1 Gene

Genomics for OR13G1 Gene

GeneHancer (GH) Regulatory Elements for OR13G1 Gene

Promoters and enhancers for OR13G1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J247854 Enhancer 1.1 FANTOM5 ENCODE 9.9 -175.8 -175768 1.5 ATF1 ARNT TCF12 ZNF766 GATA2 ATF7 NCOA1 ZNF592 SMARCA4 MYNN TRIM58 OR2T8 OR13G1 OR2W3 OR11L1
GH01J247741 Enhancer 0.4 ENCODE 10.5 -62.2 -62203 1.3 GATA3 ZSCAN4 OR13G1 OR14A16 ENSG00000235749 OR14K1 OR1C1
GH01J247647 Enhancer 0.2 ENCODE 11.4 +31.7 31660 0.9 OR13G1 OR2G3 OR2T8 TRIM58 OR3D1P LOC102724446 ENSG00000235749
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR13G1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR13G1 gene promoter:
  • Bach1
  • Brachyury
  • Nkx6-1
  • STAT5A
  • HNF-4alpha1
  • GR
  • GR-alpha
  • LCR-F1
  • Cart-1
  • GATA-1

Genomic Locations for OR13G1 Gene

Genomic Locations for OR13G1 Gene
chr1:247,670,812-247,679,739
(GRCh38/hg38)
Size:
8,928 bases
Orientation:
Minus strand
chr1:247,835,320-247,836,365
(GRCh37/hg19)
Size:
1,046 bases
Orientation:
Minus strand

Genomic View for OR13G1 Gene

Genes around OR13G1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13G1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13G1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13G1 Gene

Proteins for OR13G1 Gene

  • Protein details for OR13G1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGZ3-O13G1_HUMAN
    Recommended name:
    Olfactory receptor 13G1
    Protein Accession:
    Q8NGZ3
    Secondary Accessions:
    • B2RN80
    • Q5T2T2
    • Q6IF86

    Protein attributes for OR13G1 Gene

    Size:
    307 amino acids
    Molecular mass:
    34672 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13G1 Gene

Post-translational modifications for OR13G1 Gene

  • Glycosylation at isoforms=2
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13G1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13G1 Gene

Domains & Families for OR13G1 Gene

Gene Families for OR13G1 Gene

HGNC:
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR13G1 Gene

Suggested Antigen Peptide Sequences for OR13G1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGZ3

UniProtKB/Swiss-Prot:

O13G1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13G1: view

Function for OR13G1 Gene

Molecular function for OR13G1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004888 transmembrane signaling receptor activity IBA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR13G1: view
genes like me logo Genes that share phenotypes with OR13G1: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13G1 Gene

Localization for OR13G1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13G1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR13G1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13G1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR13G1 Gene

Pathways & Interactions for OR13G1 Gene

genes like me logo Genes that share pathways with OR13G1: view

Pathways by source for OR13G1 Gene

Interacting Proteins for OR13G1 Gene

Gene Ontology (GO) - Biological Process for OR13G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050907 detection of chemical stimulus involved in sensory perception IBA --
genes like me logo Genes that share ontologies with OR13G1: view

No data available for SIGNOR curated interactions for OR13G1 Gene

Drugs & Compounds for OR13G1 Gene

No Compound Related Data Available

Transcripts for OR13G1 Gene

mRNA/cDNA for OR13G1 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR13G1 Gene

Olfactory receptor, family 13, subfamily G, member 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13G1 Gene

No ASD Table

Relevant External Links for OR13G1 Gene

GeneLoc Exon Structure for
OR13G1
ECgene alternative splicing isoforms for
OR13G1

Expression for OR13G1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR13G1 Gene

mRNA differential expression in normal tissues according to GTEx for OR13G1 Gene

This gene is overexpressed in Testis (x27.7).

NURSA nuclear receptor signaling pathways regulating expression of OR13G1 Gene:

OR13G1

SOURCE GeneReport for Unigene cluster for OR13G1 Gene:

Hs.553834
genes like me logo Genes that share expression patterns with OR13G1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR13G1 Gene

Orthologs for OR13G1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR13G1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469749 33
  • 99.24 (n)
OR13G1 34
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR13G1 34 33
  • 85.45 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Or13g1 51 Olfr309 16 34 33
  • 84.42 (n)
rat
(Rattus norvegicus)
Mammalia Olr12 33
  • 83.12 (n)
oppossum
(Monodelphis domestica)
Mammalia OR13G1 34
  • 76 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 34
  • 52 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 46 (a)
OneToMany
-- 34
  • 45 (a)
OneToMany
Species where no ortholog for OR13G1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13G1 Gene

ENSEMBL:
Gene Tree for OR13G1 (if available)
TreeFam:
Gene Tree for OR13G1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for OR13G1: view image

Paralogs for OR13G1 Gene

Paralogs for OR13G1 Gene

(451) SIMAP similar genes for OR13G1 Gene using alignment to 1 proteins:

  • O13G1_HUMAN
genes like me logo Genes that share paralogs with OR13G1: view

Variants for OR13G1 Gene

Sequence variations from dbSNP and Humsavar for OR13G1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000886917 -- 247,674,988(-) T/C upstream_transcript_variant
rs1000923370 -- 247,671,691(-) T/G downstream_transcript_variant
rs1003654910 -- 247,671,752(-) A/G downstream_transcript_variant
rs1003722736 -- 247,673,749(-) T/C upstream_transcript_variant
rs1005340111 -- 247,674,042(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR13G1 Gene

Variant ID Type Subtype PubMed ID
dgv604n100 CNV gain 25217958
dgv605n100 CNV gain 25217958
dgv606n100 CNV gain 25217958
esv2759014 CNV gain+loss 17122850
esv2762235 CNV gain 21179565
esv33129 CNV gain+loss 17666407
esv34503 CNV gain 17911159
nsv1013273 CNV gain 25217958
nsv515858 CNV gain+loss 19592680
nsv5310 CNV deletion 18451855
nsv998451 CNV loss 25217958

Variation tolerance for OR13G1 Gene

Residual Variation Intolerance Score: 77.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 15.79; 97.36% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR13G1 Gene

Human Gene Mutation Database (HGMD)
OR13G1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR13G1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13G1 Gene

Disorders for OR13G1 Gene

Additional Disease Information for OR13G1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for OR13G1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13G1 Gene

Publications for OR13G1 Gene

  1. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. (PMID: 18599554) van der Net JB … Sijbrands EJ (European heart journal 2008) 3 22 44 58
  2. Variations of specific non-candidate genes and risk of myocardial infarction: a replication study. (PMID: 19709766) Koch W … Kastrati A (International journal of cardiology 2011) 3 44 58
  3. Usefulness of genetic polymorphisms and conventional risk factors to predict coronary heart disease in patients with familial hypercholesterolemia. (PMID: 19166692) van der Net JB … Steyerberg EW (The American journal of cardiology 2009) 3 44 58
  4. Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. (PMID: 19056482) Yoshida T … Yamada Y (Genomics 2009) 3 44 58
  5. Gene variants associated with ischemic stroke: the cardiovascular health study. (PMID: 19023099) Luke MM … Psaty BM (Stroke 2009) 3 44 58

Products for OR13G1 Gene

Sources for OR13G1 Gene

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