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Aliases for OR13C3 Gene

Aliases for OR13C3 Gene

  • Olfactory Receptor Family 13 Subfamily C Member 3 2 3 5
  • Olfactory Receptor OR9-8 3 4
  • Olfactory Receptor, Family 13, Subfamily C, Member 3 2
  • Olfactory Receptor 13C3 3
  • OR37G 3
  • OR9-8 3

External Ids for OR13C3 Gene

Previous GeneCards Identifiers for OR13C3 Gene

  • GC09U990156
  • GC09M102678
  • GC09M104377
  • GC09M106337
  • GC09M107298

Summaries for OR13C3 Gene

Entrez Gene Summary for OR13C3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13C3 Gene

OR13C3 (Olfactory Receptor Family 13 Subfamily C Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR13C4.

UniProtKB/Swiss-Prot for OR13C3 Gene

  • Odorant receptor.

Gene Wiki entry for OR13C3 Gene

Additional gene information for OR13C3 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13C3 Gene

Genomics for OR13C3 Gene

GeneHancer (GH) Regulatory Elements for OR13C3 Gene

Promoters and enhancers for OR13C3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J104906 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 6.5 -370.2 -370183 2 FOXA2 TAF1 MAX ZNF384 RAD21 YY1 POLR2A EGR1 HNF4G RXRA ABCA1 LOC105376196 OR13C3 SLC44A1 GC09M104843
GH09J104586 Enhancer 0.2 ENCODE 10.6 -49.8 -49839 0.2 NIPSNAP3A OR13C3 OR13D1 OR13D2P OR13C8
GH09J104971 Enhancer 0.2 FANTOM5 6.2 -435.1 -435075 0 OR13C3 SLC44A1 OR13C8 GC09P104984 ABCA1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR13C3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR13C3 gene promoter:
  • GATA-2
  • Tal-1
  • E47
  • C/EBPalpha
  • Nkx3-1
  • Nkx3-1 v1
  • Nkx3-1 v2
  • Nkx3-1 v3
  • Nkx3-1 v4
  • Nkx6-1

Genomic Locations for OR13C3 Gene

Genomic Locations for OR13C3 Gene
1,108 bases
Minus strand
1,108 bases
Minus strand

Genomic View for OR13C3 Gene

Genes around OR13C3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13C3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13C3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13C3 Gene

Proteins for OR13C3 Gene

  • Protein details for OR13C3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 13C3
    Protein Accession:
    Secondary Accessions:
    • Q5VVG1
    • Q6IF52

    Protein attributes for OR13C3 Gene

    347 amino acids
    Molecular mass:
    38729 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05934.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAH72411.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR13C3 Gene

Post-translational modifications for OR13C3 Gene

  • Glycosylation at isoforms=35
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13C3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13C3 Gene

Domains & Families for OR13C3 Gene

Gene Families for OR13C3 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR13C3 Gene

Suggested Antigen Peptide Sequences for OR13C3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13C3: view

Function for OR13C3 Gene

Molecular function for OR13C3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR13C3 Gene

Gene Ontology (GO) - Molecular Function for OR13C3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13C3: view
genes like me logo Genes that share phenotypes with OR13C3: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13C3 Gene

Localization for OR13C3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13C3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR13C3 gene
Compartment Confidence
plasma membrane 5
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for OR13C3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13C3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR13C3 Gene

Pathways & Interactions for OR13C3 Gene

genes like me logo Genes that share pathways with OR13C3: view

Pathways by source for OR13C3 Gene

Interacting Proteins for OR13C3 Gene

Gene Ontology (GO) - Biological Process for OR13C3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13C3: view

No data available for SIGNOR curated interactions for OR13C3 Gene

Drugs & Compounds for OR13C3 Gene

No Compound Related Data Available

Transcripts for OR13C3 Gene

mRNA/cDNA for OR13C3 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR13C3 Gene

Olfactory receptor, family 13, subfamily C, member 3:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13C3 Gene

No ASD Table

Relevant External Links for OR13C3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR13C3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR13C3 Gene

mRNA differential expression in normal tissues according to GTEx for OR13C3 Gene

This gene is overexpressed in Testis (x28.6), Liver (x7.7), Bladder (x4.4), Brain - Cortex (x4.2), and Cervix - Ectocervix (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of OR13C3 Gene:


SOURCE GeneReport for Unigene cluster for OR13C3 Gene:

genes like me logo Genes that share expression patterns with OR13C3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR13C3 Gene

Orthologs for OR13C3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13C3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC473002 33
  • 98.56 (n)
OR13C3 34
  • 97 (a)
(Canis familiaris)
Mammalia OR13C3 33
  • 88.33 (n)
-- 34
  • 72 (a)
(Bos Taurus)
Mammalia OR13C3 34 33
  • 87.17 (n)
(Mus musculus)
Mammalia Or13c3 51 Olfr273 16 34 33
  • 85.14 (n)
(Rattus norvegicus)
Mammalia LOC100912327 33
  • 84.8 (n)
(Monodelphis domestica)
Mammalia OPOR63 34
  • 83 (a)
Species where no ortholog for OR13C3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13C3 Gene

Gene Tree for OR13C3 (if available)
Gene Tree for OR13C3 (if available)
Evolutionary constrained regions (ECRs) for OR13C3: view image

Paralogs for OR13C3 Gene

(453) SIMAP similar genes for OR13C3 Gene using alignment to 1 proteins:

  • O13C3_HUMAN
genes like me logo Genes that share paralogs with OR13C3: view

Variants for OR13C3 Gene

Sequence variations from dbSNP and Humsavar for OR13C3 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000104406 -- 104,538,300(-) T/C upstream_transcript_variant
rs1000379466 -- 104,536,822(-) C/T upstream_transcript_variant
rs1000487651 -- 104,537,317(-) T/G upstream_transcript_variant
rs1001379203 -- 104,537,563(-) C/A upstream_transcript_variant
rs1003884210 -- 104,537,436(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR13C3 Gene

Variant ID Type Subtype PubMed ID
esv3891705 CNV loss 25118596
esv3891706 CNV gain 25118596
nsv466462 CNV loss 19166990
nsv615068 CNV loss 21841781
nsv831677 CNV gain 17160897

Variation tolerance for OR13C3 Gene

Residual Variation Intolerance Score: 79.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.31; 76.59% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR13C3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13C3 Gene

Disorders for OR13C3 Gene

Additional Disease Information for OR13C3

No disorders were found for OR13C3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13C3 Gene

Publications for OR13C3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. (PMID: 12906860) Hoppe R … Strotmann J (Genomics 2003) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for OR13C3 Gene

Sources for OR13C3 Gene

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