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Aliases for OR13C2 Gene

Aliases for OR13C2 Gene

  • Olfactory Receptor Family 13 Subfamily C Member 2 2 3 5
  • Olfactory Receptor OR9-12 3 4
  • Olfactory Receptor, Family 13, Subfamily C, Member 2 2
  • Olfactory Receptor 13C2 3
  • OR37K 3

External Ids for OR13C2 Gene

Previous GeneCards Identifiers for OR13C2 Gene

  • GC09U990157
  • GC09M102747
  • GC09M104446
  • GC09M106406
  • GC09M107366

Summaries for OR13C2 Gene

Entrez Gene Summary for OR13C2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13C2 Gene

OR13C2 (Olfactory Receptor Family 13 Subfamily C Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR13C5.

UniProtKB/Swiss-Prot for OR13C2 Gene

  • Odorant receptor.

Gene Wiki entry for OR13C2 Gene

Additional gene information for OR13C2 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13C2 Gene

Genomics for OR13C2 Gene

GeneHancer (GH) Regulatory Elements for OR13C2 Gene

Top Transcription factor binding sites by QIAGEN in the OR13C2 gene promoter:
  • TBP
  • POU2F1a
  • POU2F1
  • AhR
  • CP2
  • Arnt
  • aMEF-2
  • YY1
  • MEF-2A

Genomic Locations for OR13C2 Gene

Genomic Locations for OR13C2 Gene
957 bases
Minus strand
1,028 bases
Minus strand

Genomic View for OR13C2 Gene

Genes around OR13C2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13C2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13C2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13C2 Gene

Proteins for OR13C2 Gene

  • Protein details for OR13C2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 13C2
    Protein Accession:
    Secondary Accessions:
    • B9EGV8
    • Q6IF54

    Protein attributes for OR13C2 Gene

    318 amino acids
    Molecular mass:
    35694 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR13C2 Gene

Post-translational modifications for OR13C2 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13C2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR13C2 Gene

Domains & Families for OR13C2 Gene

Gene Families for OR13C2 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR13C2 Gene

Suggested Antigen Peptide Sequences for OR13C2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13C2: view

Function for OR13C2 Gene

Molecular function for OR13C2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13C2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR13C2: view
genes like me logo Genes that share phenotypes with OR13C2: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13C2 Gene

Localization for OR13C2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13C2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR13C2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13C2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR13C2: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR13C2 Gene

Pathways & Interactions for OR13C2 Gene

genes like me logo Genes that share pathways with OR13C2: view

Pathways by source for OR13C2 Gene

Interacting Proteins for OR13C2 Gene

Gene Ontology (GO) - Biological Process for OR13C2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13C2: view

No data available for SIGNOR curated interactions for OR13C2 Gene

Drugs & Compounds for OR13C2 Gene

No Compound Related Data Available

Transcripts for OR13C2 Gene

mRNA/cDNA for OR13C2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR13C2 Gene

Olfactory receptor, family 13, subfamily C, member 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13C2 Gene

No ASD Table

Relevant External Links for OR13C2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR13C2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR13C2 Gene

mRNA differential expression in normal tissues according to GTEx for OR13C2 Gene

This gene is overexpressed in Pituitary (x16.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OR13C2 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR13C2 Gene:


SOURCE GeneReport for Unigene cluster for OR13C2 Gene:

genes like me logo Genes that share expression patterns with OR13C2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR13C2 Gene

Orthologs for OR13C2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR13C2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC737408 33
  • 99.48 (n)
(Canis familiaris)
Mammalia OR13C2 33
  • 89.78 (n)
(Bos Taurus)
Mammalia LOC789943 33
  • 88.26 (n)
(Rattus norvegicus)
Mammalia Olr852 33
  • 81.2 (n)
Species where no ortholog for OR13C2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13C2 Gene

Gene Tree for OR13C2 (if available)
Gene Tree for OR13C2 (if available)
Evolutionary constrained regions (ECRs) for OR13C2: view image

Paralogs for OR13C2 Gene

(451) SIMAP similar genes for OR13C2 Gene using alignment to 1 proteins:

  • O13C2_HUMAN Pseudogenes for OR13C2 Gene

genes like me logo Genes that share paralogs with OR13C2: view

Variants for OR13C2 Gene

Sequence variations from dbSNP and Humsavar for OR13C2 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000065931 -- 104,605,687(-) G/A upstream_transcript_variant
rs1000077260 -- 104,606,037(-) T/G upstream_transcript_variant
rs1001033040 -- 104,607,265(-) T/A upstream_transcript_variant
rs1001086695 -- 104,607,466(-) G/C upstream_transcript_variant
rs1006606925 -- 104,606,148(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR13C2 Gene

Variant ID Type Subtype PubMed ID
dgv1364e199 CNV deletion 23128226
dgv1365e199 CNV deletion 23128226
dgv144e19 CNV loss 19470904
dgv1497e214 CNV gain 21293372
dgv1498e214 CNV loss 21293372
dgv150n17 CNV loss 16327808
dgv2174e212 CNV loss 25503493
dgv7696n100 CNV gain 25217958
dgv7697n100 CNV loss 25217958
esv22412 CNV loss 19812545
esv2546770 CNV deletion 19546169
esv2664971 CNV deletion 23128226
esv2676803 CNV deletion 23128226
esv2738875 CNV deletion 23290073
esv2738876 CNV deletion 23290073
esv2759707 CNV gain+loss 17122850
esv2761260 CNV gain+loss 21179565
esv3545239 CNV deletion 23714750
esv3621332 CNV loss 21293372
esv3621335 CNV loss 21293372
esv3621337 CNV gain 21293372
esv3891705 CNV loss 25118596
esv3891706 CNV gain 25118596
esv5880 CNV loss 19470904
nsv1117900 CNV deletion 24896259
nsv436624 CNV deletion 17901297
nsv471313 CNV loss 18288195
nsv524181 CNV loss 19592680
nsv831677 CNV gain 17160897
nsv8556 CNV loss 18304495
nsv982333 CNV duplication 23825009
nsv982597 OTHER complex 23825009

Variation tolerance for OR13C2 Gene

Residual Variation Intolerance Score: 89.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 25.92; 99.74% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR13C2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13C2 Gene

Disorders for OR13C2 Gene

Additional Disease Information for OR13C2

No disorders were found for OR13C2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13C2 Gene

Publications for OR13C2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. (PMID: 12906860) Hoppe R … Strotmann J (Genomics 2003) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for OR13C2 Gene

Sources for OR13C2 Gene

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