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Aliases for OR13A1 Gene

Aliases for OR13A1 Gene

  • Olfactory Receptor Family 13 Subfamily A Member 1 2 3 5
  • Olfactory Receptor OR10-3 3 4
  • Olfactory Receptor, Family 13, Subfamily A, Member 1 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor 13A1 3

External Ids for OR13A1 Gene

Previous GeneCards Identifiers for OR13A1 Gene

  • GC10U990104
  • GC10M045083
  • GC10M045118
  • GC10M045798
  • GC10M042323

Summaries for OR13A1 Gene

Entrez Gene Summary for OR13A1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR13A1 Gene

OR13A1 (Olfactory Receptor Family 13 Subfamily A Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR13G1.

UniProtKB/Swiss-Prot for OR13A1 Gene

  • Odorant receptor.

Gene Wiki entry for OR13A1 Gene

Additional gene information for OR13A1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR13A1 Gene

Genomics for OR13A1 Gene

GeneHancer (GH) Regulatory Elements for OR13A1 Gene

Promoters and enhancers for OR13A1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J045373 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 12.8 -59.6 -59609 4.3 PKNOX1 ZNF121 ZNF766 GLIS2 ZNF143 FOS ATF7 RUNX3 ZNF263 SP3 ALOX5 WASHC2C PARGP1 OR13A1 FAM21FP AGAP4 AGAP10P ZFAND4 GC10M045391 GC10M045366
GH10J045378 Enhancer 1 FANTOM5 ENCODE dbSUPER 14.2 -64.3 -64334 2 ATF4 POLR2A EED MAX MYC RUNX3 OR13A1 ALOX5 WASHC2C GC10M045391 GC10M045366
GH10J045353 Enhancer 0.8 FANTOM5 ENCODE 14.2 -38.8 -38825 1.1 RFX1 L3MBTL2 CEBPG FOSL1 POLR2A IKZF1 NFE2 RUNX3 OR13A1 ALOX5
GH10J045278 Enhancer 0.9 ENCODE 12.1 +36.3 36331 1.5 HDGF PKNOX1 ATF1 ARNT TCF12 ZNF766 CBX5 GATA2 ATF7 NCOA1 OR13A1 MARCH8 GC10M045298 PIR41722
GH10J045418 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 6.2 -105.1 -105110 5.2 HDGF SMAD1 BATF IRF4 RAD21 ZNF335 SCRT2 ZNF143 ATF7 ETV6 ALOX5 AGAP4 ZFAND4 LOC102724323 WASHC2C MARCH8 OR13A1 GC10M045366 GC10P045436
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR13A1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR13A1 gene promoter:
  • FOXL1
  • RP58
  • LHX3b
  • Lhx3a
  • Nkx6-1
  • PPAR-gamma2
  • PPAR-gamma1
  • MEF-2A
  • aMEF-2
  • Cdc5

Genomic Locations for OR13A1 Gene

Genomic Locations for OR13A1 Gene
13,315 bases
Minus strand
12,955 bases
Minus strand

Genomic View for OR13A1 Gene

Genes around OR13A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR13A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR13A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR13A1 Gene

Proteins for OR13A1 Gene

  • Protein details for OR13A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 13A1
    Protein Accession:
    Secondary Accessions:
    • Q2M3M4
    • Q5VV57
    • Q6IFH5
    • Q6ZMN6

    Protein attributes for OR13A1 Gene

    328 amino acids
    Molecular mass:
    36494 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05949.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAH73801.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR13A1 Gene

Post-translational modifications for OR13A1 Gene

  • Glycosylation at Asn23
  • Modification sites at PhosphoSitePlus

Other Protein References for OR13A1 Gene

No data available for DME Specific Peptides for OR13A1 Gene

Domains & Families for OR13A1 Gene

Gene Families for OR13A1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR13A1 Gene

Suggested Antigen Peptide Sequences for OR13A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR13A1: view

Function for OR13A1 Gene

Molecular function for OR13A1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR13A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR13A1: view
genes like me logo Genes that share phenotypes with OR13A1: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR13A1 Gene

Localization for OR13A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR13A1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR13A1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR13A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR13A1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR13A1 Gene

Pathways & Interactions for OR13A1 Gene

genes like me logo Genes that share pathways with OR13A1: view

Pathways by source for OR13A1 Gene

Interacting Proteins for OR13A1 Gene

Gene Ontology (GO) - Biological Process for OR13A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA,IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR13A1: view

No data available for SIGNOR curated interactions for OR13A1 Gene

Drugs & Compounds for OR13A1 Gene

No Compound Related Data Available

Transcripts for OR13A1 Gene

mRNA/cDNA for OR13A1 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR13A1 Gene

Olfactory receptor, family 13, subfamily A, member 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR13A1 Gene

No ASD Table

Relevant External Links for OR13A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR13A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR13A1 Gene

mRNA differential expression in normal tissues according to GTEx for OR13A1 Gene

This gene is overexpressed in Bladder (x6.9) and Spleen (x4.1).

NURSA nuclear receptor signaling pathways regulating expression of OR13A1 Gene:


SOURCE GeneReport for Unigene cluster for OR13A1 Gene:


Evidence on tissue expression from TISSUES for OR13A1 Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with OR13A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR13A1 Gene

Orthologs for OR13A1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR13A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466062 33
  • 98.17 (n)
OR13A1 34
  • 97 (a)
(Canis familiaris)
Mammalia OR13A1 34 33
  • 85.37 (n)
(Bos Taurus)
Mammalia OR13A1 34 33
  • 84.65 (n)
(Mus musculus)
Mammalia Or13a1 51 Olfr211 16 34 33
  • 84.03 (n)
Or12j2 51 Olfr527
  • chr7:140,335,864-140,336,778
Or12j3 51 Olfr530
  • chr7:140,372,688-140,373,608
Or12j4 51 Olfr533
  • chr7:140,466,203-140,467,162
Or12j5 51 Olfr536
  • chr7:140,503,537-140,504,457
Or13a17 51 Olfr45
  • chr7:140,690,907-140,691,839
Or13a18 51 Olfr46
  • chr7:140,610,168-140,611,121
Or13a19 51 Olfr525
  • chr7:140,322,701-140,323,627
Or13a20 51 Olfr53
  • chr7:140,651,981-140,652,916
Or13a21 51 Olfr532
  • chr7:140,418,845-140,419,771
Or13a22 51 Olfr535
  • chr7:140,492,640-140,493,575
Or13a23-ps 51 Olfr537-ps1
  • chr7:140,538,495-140,539,441
Or13a24 51 Olfr538
  • chr7:140,574,131-140,575,084
Or13a25 51 Olfr539
  • chr7:140,667,289-140,668,245
Or13a26 51 Olfr541
  • chr7:140,704,253-140,705,188
Or13a27 51 Olfr60
  • chr7:140,345,055-140,345,987
Or13a28 51 Olfr61
  • chr7:140,637,703-140,638,635
Or13o1-ps 51 Olfr528-ps1
  • chr7:140,341,490-140,342,204
Or13v11 51 Olfr531
  • chr7:140,400,133-140,401,044
Or13x1-ps 51 Olfr534-ps1
  • chr7:140,478,811-140,479,565
(Rattus norvegicus)
Mammalia Olr823 33
  • 83.12 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 76 (a)
-- 34
  • 74 (a)
-- 34
  • 72 (a)
-- 34
  • 72 (a)
-- 34
  • 72 (a)
-- 34
  • 63 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 46 (a)
Species where no ortholog for OR13A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR13A1 Gene

Gene Tree for OR13A1 (if available)
Gene Tree for OR13A1 (if available)
Evolutionary constrained regions (ECRs) for OR13A1: view image

Paralogs for OR13A1 Gene

Paralogs for OR13A1 Gene

(450) SIMAP similar genes for OR13A1 Gene using alignment to 1 proteins:

  • O13A1_HUMAN Pseudogenes for OR13A1 Gene

genes like me logo Genes that share paralogs with OR13A1: view

Variants for OR13A1 Gene

Sequence variations from dbSNP and Humsavar for OR13A1 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1000526483 -- 45,315,985(-) T/G upstream_transcript_variant
rs1000726436 -- 45,310,563(-) C/T 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant
rs1000906165 -- 45,305,419(-) A/G intron_variant
rs1000951249 -- 45,310,889(-) T/G 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant
rs1001141411 -- 45,305,467(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for OR13A1 Gene

Variant ID Type Subtype PubMed ID
esv2750897 CNV loss 17911159
esv3623082 CNV gain 21293372
esv3891797 CNV gain 25118596

Variation tolerance for OR13A1 Gene

Residual Variation Intolerance Score: 69.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.22; 84.93% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR13A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR13A1 Gene

Disorders for OR13A1 Gene

Additional Disease Information for OR13A1

No disorders were found for OR13A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR13A1 Gene

Publications for OR13A1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for OR13A1 Gene

Sources for OR13A1 Gene

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