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Aliases for OR11H7 Gene

Aliases for OR11H7 Gene

  • Olfactory Receptor Family 11 Subfamily H Member 7 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 11, Subfamily H, Member 7 Pseudogene 2 3
  • Olfactory Receptor OR14-32 3 4
  • OR11H7P 3 4
  • Olfactory Receptor, Family 11, Subfamily H, Member 7 (Gene/Pseudogene) 2
  • Olfactory Receptor 11H7 3

External Ids for OR11H7 Gene

Previous HGNC Symbols for OR11H7 Gene

  • OR11H7P

Previous GeneCards Identifiers for OR11H7 Gene

  • GC14P019768
  • GC14P020697
  • GC14P000819

Summaries for OR11H7 Gene

Entrez Gene Summary for OR11H7 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

GeneCards Summary for OR11H7 Gene

OR11H7 (Olfactory Receptor Family 11 Subfamily H Member 7 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR11H4.

UniProtKB/Swiss-Prot for OR11H7 Gene

  • Odorant receptor. Activated by isovaleric acid.

Additional gene information for OR11H7 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR11H7 Gene

Genomics for OR11H7 Gene

GeneHancer (GH) Regulatory Elements for OR11H7 Gene

Promoters and enhancers for OR11H7 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I020798 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 5.8 +571.5 571504 5.6 PKNOX1 ATF1 ARNT NCOA2 TCF12 ZNF766 NCOA1 ZNF592 ZNF184 SMARCA4 RNASE1 OR11H7 LOC105370397
GH14I021092 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 4.6 +872.0 872024 18.3 CLOCK MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF219 TMEM253 METTL3 METTL17 SUPT16H CHD8 TEP1 APEX1 PNP ARHGEF40
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around OR11H7 on UCSC Golden Path with GeneCards custom track

Genomic Locations for OR11H7 Gene

Genomic Locations for OR11H7 Gene
945 bases
Plus strand

Genomic View for OR11H7 Gene

Genes around OR11H7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR11H7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR11H7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR11H7 Gene

Proteins for OR11H7 Gene

  • Protein details for OR11H7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 11H7
    Protein Accession:

    Protein attributes for OR11H7 Gene

    314 amino acids
    Molecular mass:
    35499 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR11H7 Gene

Post-translational modifications for OR11H7 Gene

Other Protein References for OR11H7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OR11H7 Gene

Domains & Families for OR11H7 Gene

Gene Families for OR11H7 Gene

Protein Domains for OR11H7 Gene

Suggested Antigen Peptide Sequences for OR11H7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR11H7: view

Function for OR11H7 Gene

Molecular function for OR11H7 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor. Activated by isovaleric acid.

Gene Ontology (GO) - Molecular Function for OR11H7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004984 olfactory receptor activity IEA --
GO:0004993 G-protein coupled serotonin receptor activity IBA --
GO:0030594 neurotransmitter receptor activity IBA --
genes like me logo Genes that share ontologies with OR11H7: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR11H7 Gene

Localization for OR11H7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR11H7 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR11H7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR11H7: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR11H7 Gene

Pathways & Interactions for OR11H7 Gene

genes like me logo Genes that share pathways with OR11H7: view

Pathways by source for OR11H7 Gene

Interacting Proteins for OR11H7 Gene

Gene Ontology (GO) - Biological Process for OR11H7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway TAS --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
GO:0098664 G-protein coupled serotonin receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with OR11H7: view

No data available for SIGNOR curated interactions for OR11H7 Gene

Drugs & Compounds for OR11H7 Gene

No Compound Related Data Available

Transcripts for OR11H7 Gene

mRNA/cDNA for OR11H7 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR11H7 Gene

No ASD Table

Relevant External Links for OR11H7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR11H7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR11H7 Gene

mRNA differential expression in normal tissues according to GTEx for OR11H7 Gene

This gene is overexpressed in Testis (x6.0).

NURSA nuclear receptor signaling pathways regulating expression of OR11H7 Gene:

genes like me logo Genes that share expression patterns with OR11H7: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR11H7 Gene

Orthologs for OR11H7 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR11H7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR11H7 34
  • 83 (a)
(Mus musculus)
Mammalia Or11h7 51 Olfr746 34
  • 80 (a)
Or11h23 51 Olfr748 34
  • 80 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 61 (a)
(Canis familiaris)
Mammalia -- 34
  • 57 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 56 (a)
Species where no ortholog for OR11H7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR11H7 Gene

Gene Tree for OR11H7 (if available)
Gene Tree for OR11H7 (if available)

Paralogs for OR11H7 Gene

Paralogs for OR11H7 Gene

(456) SIMAP similar genes for OR11H7 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR11H7: view

Variants for OR11H7 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR11H7 Gene

A stop codon in the gene coding for this protein at position Gln-227 is responsible for functional diversity thus producing a pseudogene. Hypersensitivity towards isovaleric acid is seen predominantly in individuals who carry at least one copy of the intact allele.

Additional Variant Information for OR11H7 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR11H7 Gene

Disorders for OR11H7 Gene

Additional Disease Information for OR11H7

No disorders were found for OR11H7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR11H7 Gene

Publications for OR11H7 Gene

  1. Genetic elucidation of human hyperosmia to isovaleric acid. (PMID: 17973576) Menashe I … Lancet D (PLoS biology 2007) 3 4 58
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  3. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R … Weissenbach J (Nature 2003) 3 4 58
  4. Different noses for different people. (PMID: 12730696) Menashe I … Gilad Y (Nature genetics 2003) 3 4 58
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4 58

Products for OR11H7 Gene

Sources for OR11H7 Gene

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