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Aliases for OR10P1 Gene

Aliases for OR10P1 Gene

  • Olfactory Receptor Family 10 Subfamily P Member 1 2 3 5
  • Olfactory Receptor OR12-7 3 4
  • Olfactory Receptor 10P2 3 4
  • Olfactory Receptor 10P3 3 4
  • OR10P1P 3 4
  • OR10P2P 3 4
  • OR10P3P 3 4
  • Olfactory Receptor, Family 10, Subfamily P, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily P, Member 2 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily P, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 10, Subfamily P, Member 1 2
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor 10P1 3
  • OR12-7 3
  • OST701 3

External Ids for OR10P1 Gene

Previous HGNC Symbols for OR10P1 Gene

  • OR10P1P
  • OR10P2P
  • OR10P3P

Previous GeneCards Identifiers for OR10P1 Gene

  • GC12P054317
  • GC12P054318
  • GC12P056030

Summaries for OR10P1 Gene

Entrez Gene Summary for OR10P1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10P1 Gene

OR10P1 (Olfactory Receptor Family 10 Subfamily P Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR10P1 Gene

  • Odorant receptor.

Gene Wiki entry for OR10P1 Gene

Additional gene information for OR10P1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR10P1 Gene

Genomics for OR10P1 Gene

GeneHancer (GH) Regulatory Elements for OR10P1 Gene

Promoters and enhancers for OR10P1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I055635 Enhancer 0.2 dbSUPER 557.3 +0.3 319 3.7 OR10P1 OR10AE3P ENSG00000258921 OR6C70
GH12I056040 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 4.1 +405.1 405139 3.3 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 RPS26 LOC105369780 BAZ2A RN7SL809P STAT2 PAN2 ENSG00000258199 ZC3H10 CDK2 ENSG00000257740
GH12I055645 Enhancer 1.4 Ensembl ENCODE dbSUPER 6.1 +9.7 9712 1.9 HDGF ARNT ZNF2 YY1 POLR2B ZNF766 ZNF213 ZNF416 ZNF207 ZNF143 OR10AE3P SMARCC2 ANKRD52 PHC1P1 DNAJC14 IKZF4 PAN2 TMEM198B IL23A ENSG00000257740
GH12I055680 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 4.9 +45.2 45159 2.4 ARID4B SIN3A DMAP1 ZNF48 ETS1 YY1 GLIS2 ATF7 SP3 RXRA METTL7B PAN2 PHC1P1 ENSG00000257509 DNAJC14 TMEM198B SMARCC2 CNPY2 ANKRD52 OR10P1
GH12I055711 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE dbSUPER 5.1 +76.1 76141 2.6 NFIB JUN CEBPB ATF2 JUND NFIC CREB1 HNF4A ATF7 FOS ITGA7 BLOC1S1 OR10P1 BLOC1S1-RDH5 METTL7B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around OR10P1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the OR10P1 gene promoter:

Genomic Locations for OR10P1 Gene

Genomic Locations for OR10P1 Gene
995 bases
Plus strand

Genomic View for OR10P1 Gene

Genes around OR10P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10P1 Gene

Proteins for OR10P1 Gene

  • Protein details for OR10P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 10P1
    Protein Accession:
    Secondary Accessions:
    • B9EGY4

    Protein attributes for OR10P1 Gene

    313 amino acids
    Molecular mass:
    34741 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10P1 Gene

Post-translational modifications for OR10P1 Gene

Other Protein References for OR10P1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR10P1 Gene

Domains & Families for OR10P1 Gene

Gene Families for OR10P1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR10P1 Gene

Suggested Antigen Peptide Sequences for OR10P1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10P1: view

Function for OR10P1 Gene

Molecular function for OR10P1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR10P1 Gene

Gene Ontology (GO) - Molecular Function for OR10P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR10P1: view

Phenotypes for OR10P1 Gene

GenomeRNAi human phenotypes for OR10P1:
genes like me logo Genes that share phenotypes with OR10P1: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10P1 Gene

Localization for OR10P1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10P1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR10P1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR10P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR10P1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR10P1 Gene

Pathways & Interactions for OR10P1 Gene

genes like me logo Genes that share pathways with OR10P1: view

Pathways by source for OR10P1 Gene

Interacting Proteins for OR10P1 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 12)
Selected Interacting proteins: ENSP00000308082 Q8NGE3-O10P1_HUMAN for OR10P1 Gene via STRING IID

Gene Ontology (GO) - Biological Process for OR10P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway TAS --
GO:0007608 sensory perception of smell IBA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR10P1: view

No data available for SIGNOR curated interactions for OR10P1 Gene

Drugs & Compounds for OR10P1 Gene

No Compound Related Data Available

Transcripts for OR10P1 Gene

mRNA/cDNA for OR10P1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR10P1 Gene

No ASD Table

Relevant External Links for OR10P1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR10P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR10P1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OR10P1 Gene

This gene is overexpressed in Heart - Atrial Appendage (x40.4).

NURSA nuclear receptor signaling pathways regulating expression of OR10P1 Gene:


SOURCE GeneReport for Unigene cluster for OR10P1 Gene:

genes like me logo Genes that share expression patterns with OR10P1: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10P1 Gene

Orthologs for OR10P1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR10P1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR10P1 33 34
  • 87.18 (n)
(Mus musculus)
Mammalia Or10p1 51 Olfr796 33 16 34
  • 82.9 (n)
Or10p21 51 Olfr763
  • chr10:129,011,287-129,012,213
Or10p22 51 Olfr9
  • chr10:128,989,914-128,990,849
(Rattus norvegicus)
Mammalia Olr1016 33
  • 80.87 (n)
(Monodelphis domestica)
Mammalia -- 34
  • 57 (a)
(Anolis carolinensis)
Reptilia OR10P1 34
  • 48 (a)
Species where no ortholog for OR10P1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR10P1 Gene

Gene Tree for OR10P1 (if available)
Gene Tree for OR10P1 (if available)

Paralogs for OR10P1 Gene

(450) SIMAP similar genes for OR10P1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR10P1: view

No data available for Paralogs for OR10P1 Gene

Variants for OR10P1 Gene

Sequence variations from dbSNP and Humsavar for OR10P1 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000076142 -- 55,635,803(+) A/T upstream_transcript_variant
rs1000126683 -- 55,635,492(+) C/A upstream_transcript_variant
rs1001937327 -- 55,636,606(+) A/G upstream_transcript_variant
rs1003925264 -- 55,636,186(+) C/T upstream_transcript_variant
rs1003989581 -- 55,636,742(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for OR10P1 Gene

Variant ID Type Subtype PubMed ID
nsv559001 CNV loss 21841781

Variation tolerance for OR10P1 Gene

Residual Variation Intolerance Score: 83.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.80; 79.11% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR10P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR10P1 Gene

Disorders for OR10P1 Gene

Additional Disease Information for OR10P1

No disorders were found for OR10P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR10P1 Gene

Publications for OR10P1 Gene

  1. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 3 4 58
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 58
  3. Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia. (PMID: 24152035) Goodbourn PT … Mollon JD (Genes, brain, and behavior 2014) 3 58
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 58

Products for OR10P1 Gene

Sources for OR10P1 Gene

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