Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone rec... See more...

Aliases for OR10J6P Gene

Aliases for OR10J6P Gene

  • Olfactory Receptor Family 10 Subfamily J Member 6 Pseudogene 2 3 5
  • OR10J6 3 4
  • Olfactory Receptor, Family 10, Subfamily J, Member 6 Pseudogene 2
  • Seven Transmembrane Helix Receptor 3
  • Putative Olfactory Receptor 10J6 4
  • Olfactory Receptor 10J6 3
  • OR10J6P 5

External Ids for OR10J6P Gene

Previous HGNC Symbols for OR10J6P Gene

  • OR10J6

Previous GeneCards Identifiers for OR10J6P Gene

  • GC01P156785
  • GC01P156381
  • GC01P157834
  • GC01P159567

Summaries for OR10J6P Gene

Entrez Gene Summary for OR10J6P Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR10J6P Gene

OR10J6P (Olfactory Receptor Family 10 Subfamily J Member 6 Pseudogene) is a Pseudogene. Among its related pathways are Signaling by GPCR and Olfactory transduction. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot Summary for OR10J6P Gene

Additional gene information for OR10J6P Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for OR10J6P Gene

Genomics for OR10J6P Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for OR10J6P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J159594 Enhancer 0.8 Ensembl ENCODE 257.6 -1.5 -1531 5.1 YY1 CEBPB EP300 FOXA2 RAD21 ZBTB33 STAT3 JUND HNF4A FOXA1 OR10J6P OR10J5 OR10J3 DUSP23 SLAMF9 APCS HSALNG0007773 CRP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around OR10J6P on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for OR10J6P Gene

Latest Assembly
chr1:159,598,298-159,599,227
(GRCh38/hg38)
Size:
930 bases
Orientation:
Plus strand

Previous Assembly
chr1:159,568,089-159,569,015
(GRCh37/hg19 by Entrez Gene)
Size:
927 bases
Orientation:
Plus strand

chr1:159,568,088-159,569,017
(GRCh37/hg19 by Ensembl)
Size:
930 bases
Orientation:
Plus strand

Genomic View for OR10J6P Gene

Genes around OR10J6P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR10J6P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR10J6P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR10J6P Gene

Proteins for OR10J6P Gene

  • Protein details for OR10J6P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGY7-O10J6_HUMAN
    Recommended name:
    Putative olfactory receptor 10J6
    Protein Accession:
    Q8NGY7
    Secondary Accessions:
    • Q96R55

    Protein attributes for OR10J6P Gene

    Size:
    276 amino acids
    Molecular mass:
    31021 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR10J6P Gene

Post-translational modifications for OR10J6P Gene

  • Glycosylation at Asn5 and Asn190

Other Protein References for OR10J6P Gene

HORDE protein sequence:

No data available for DME Specific Peptides for OR10J6P Gene

Domains & Families for OR10J6P Gene

Gene Families for OR10J6P Gene

Protein Domains for OR10J6P Gene

Suggested Antigen Peptide Sequences for OR10J6P Gene

GenScript: Design optimal peptide antigens:
  • Putative olfactory receptor 10J6 (O10J6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8NGY7

UniProtKB/Swiss-Prot:

O10J6_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR10J6P: view

Function for OR10J6P Gene

Molecular function for OR10J6P Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes From GWAS Catalog for OR10J6P Gene

Gene Ontology (GO) - Molecular Function for OR10J6P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004984 olfactory receptor activity IEA --
GO:0004993 G protein-coupled serotonin receptor activity IBA 21873635
GO:0030594 neurotransmitter receptor activity IBA 21873635
genes like me logo Genes that share ontologies with OR10J6P: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR10J6P Gene

Localization for OR10J6P Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR10J6P Gene

Cell membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR10J6P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA 21873635
GO:0030425 dendrite IBA 21873635
GO:0045202 synapse IEA --
genes like me logo Genes that share ontologies with OR10J6P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR10J6P Gene

Pathways & Interactions for OR10J6P Gene

PathCards logo

SuperPathways for OR10J6P Gene

genes like me logo Genes that share pathways with OR10J6P: view

Pathways by source for OR10J6P Gene

Gene Ontology (GO) - Biological Process for OR10J6P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA 21873635
GO:0007268 chemical synaptic transmission IBA 21873635
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
GO:0098664 G protein-coupled serotonin receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with OR10J6P: view

No data available for Interacting Proteins and SIGNOR curated interactions for OR10J6P Gene

Drugs & Compounds for OR10J6P Gene

No Compound Related Data Available

Transcripts for OR10J6P Gene

mRNA/cDNA for OR10J6P Gene

1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR10J6P Gene

No ASD Table

Relevant External Links for OR10J6P Gene

GeneLoc Exon Structure for
OR10J6P

Expression for OR10J6P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR10J6P Gene

mRNA differential expression in normal tissues according to GTEx for OR10J6P Gene

This gene is overexpressed in Liver (x52.4).
genes like me logo Genes that share expression patterns with OR10J6P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR10J6P Gene

Orthologs for OR10J6P Gene

Evolution for OR10J6P Gene

ENSEMBL:
Gene Tree for OR10J6P (if available)
TreeFam:
Gene Tree for OR10J6P (if available)
Alliance of Genome Resources:
Additional Orthologs for OR10J6P

No data available for Orthologs for OR10J6P Gene

Paralogs for OR10J6P Gene

(446) SIMAP similar genes for OR10J6P Gene using alignment to 1 proteins:

  • O10J6_HUMAN
genes like me logo Genes that share paralogs with OR10J6P: view

No data available for Paralogs for OR10J6P Gene

Variants for OR10J6P Gene

Additional Variant Information for OR10J6P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR10J6P
Leiden Open Variation Database (LOVD)
OR10J6P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR10J6P Gene

Disorders for OR10J6P Gene

No disorders were found for OR10J6P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for OR10J6P Gene

Publications for OR10J6P Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T … Shamir R (Genomics 2002) 3 4
  2. C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans. (PMID: 22492993) Doumatey AP … Rotimi CN (Human molecular genetics 2012) 40
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  4. A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PMID: 18464913) Melzer D … Ferrucci L (PLoS genetics 2008) 40

Products for OR10J6P Gene

Sources for OR10J6P Gene